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Senior Python Developer Jobs in Maryland (NOW HIRING)

Python Integration Developer

Hanover, MD · On-site +1

$50 - $69/hr

Mid-Senior It's a W2 Role Job Summary We are seeking an experienced Integration Developer with strong Python development skills to build and support enterprise integrations across cloud platforms and ...

Senior Python Software Engineer

Laurel, MD · On-site

$170K - $230K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Are you a Senior Software Engineer who is ready for a new challenge that will launch your career to ... DevOps Containerization. We also provide customer solutions in the areas of CND, CNE, and CNO by ...

Senior Python Software Engineer

Laurel, MD · On-site

$170K - $230K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Are you a Senior Software Engineer who is ready for a new challenge that will launch your career to ... DevOps Containerization. We also provide customer solutions in the areas of CND, CNE, and CNO by ...

Senior Python Software Engineer

Laurel, MD · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Are you a Senior Software Engineer who is ready for a new challenge that will launch your career to ... DevOps Containerization. We also provide customer solutions in the areas of CND, CNE, and CNO by ...

Senior Python Software Engineer

Laurel, MD · On-site

$170 - $230/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

GliaCell is seeking a Senior Software Engineer on one of our subcontracts. This is a full-time ... Experience with Python * Experience with GM Learn * Exploratory Data Analysis (EDA) * Experience ...

SQL/Python System Designer III

Columbia, MD · Hybrid

$50.50 - $69.50/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The role requires cross-functional collaboration , engagement with senior stakeholders, and the ... Python Developer to serve as a key liaison between Business Operations and Technology teams ...

SQL/Python System Designer IV

Columbia, MD · On-site

$50.50 - $69.50/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The position partners closely with senior leadership to identify key business challenges and drive ... Python Developer to serve as a key liaison between Business Operations and Technology teams ...

SQL/Python System Designer III

Columbia, MD · On-site

$50.50 - $69.50/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The role requires cross-functional collaboration , engagement with senior stakeholders, and the ... Python Developer to serve as a key liaison between Business Operations and Technology teams ...

SQL/Python System Designer IV

Columbia, MD · Hybrid

$50.50 - $69.50/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

The position partners closely with senior leadership to identify key business challenges and drive ... Python Developer to serve as a key liaison between Business Operations and Technology teams ...

Sr Software Developer

Annapolis Junction, MD

$174K - $220K/yr

  • Medical

  • Retirement

  • PTO

ELEVI is seeking a Senior Software Engineer to support the Cybersecurity Infrastructure (CI) TTO ... Strong Java, Python developer skills Parsing and extraction: Regex/pattern matching, data parsing ...

Sr Software Developer

Annapolis, MD · On-site

$174K - $220K/yr

  • Medical

  • Retirement

  • PTO

ELEVI is seeking a Senior Software Engineer to support the Cybersecurity Infrastructure (CI) TTO ... Strong Java, Python developer skills • Parsing and extraction: Regex/pattern matching, data ...

Showing results 21-40

Senior Python Developer information

See Maryland salary details

$53.4K

$137.8K

$189.3K

How much do senior python developer jobs pay per year?

As of Aug 18, 2026, the average yearly pay for senior python developer in Maryland is $137,793.00, according to ZipRecruiter salary data. Most workers in this role earn between $117,900.00 and $158,700.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are the most commonly searched types of Python Developer jobs in Maryland?

The most popular types of Python Developer jobs in Maryland are:

What are popular job titles related to Senior Python Developer jobs in Maryland?

For Senior Python Developer jobs in Maryland, the most frequently searched job titles are:

What cities in Maryland are hiring for Senior Python Developer jobs?

Cities in Maryland with the most Senior Python Developer job openings:

What are popular job titles related to Senior Python Developer jobs in MD?

For Senior Python Developer jobs in MD, the most frequently searched job titles are:

Infographic showing various Senior Python Developer job openings in Maryland as of August 2026, with employment types broken down into 1% Internship, 85% Full Time, 9% Part Time, and 5% Contract. Highlights an 76% Physical, 7% Hybrid, and 17% Remote job distribution, with an average salary of $137,793 per year, or $66.2 per hour.

Sr. Python Full Stack Developer wit AI - MD Onsite

Tek Hire Solutions

Woodlawn, MD • On-site

$90K - $130K/yr

Full-time

Re-posted 4 days ago


Job description


Role: Sr. Python Full Stack Developer  with AI
Location: Woodlawn, MD (Onsite) 

ONSITE Interview – 2nd/ final round
6-8 week suitability process – must be in the US since the last 3 years minimum
Technical Assessment Required
 
Required Conditions
  • Selected candidate must be able to obtain and maintain a public trust clearance
  • Selected candidate must be willing to work on-site in Woodlawn, MD 5 days a week
  • Master's and 5+ years of experience, Bachelor's and 7+ years of experience or 13+ years in lieu of a degree
Position Description
Generative AI Solution Development
  • Collaborate with stakeholders to understand and refine customer-provided use cases for Generative AI solutions.
  • Design, develop, and implement end-to-end Proofs of Concept (PoCs) using Azure AI and AWS Bedrock platforms.
  • Build and maintain scalable, secure, and robust web applications, integrating Generative AI models and APIs.
  • Develop both front-end and back-end components, ensuring seamless user experience and efficient data processing.
  • Rapidly prototype and iterate on application features based on feedback and evolving requirements.
Skills Requirements
Foundation for Success (Basic Qualifications)
Full Stack & Software Development
  • 5+ years of experience in full stack development, including both front-end and back-end technologies.
  • 3+ years of experience in Python development. You should be comfortable writing clean, efficient code.
  • Proficiency in programming languages such as Python, JavaScript (Node.js, React, or Angular), or similar technologies.
  • Experience with RESTful APIs, microservices architecture, and containerization (e.g., OpenShift or Docker).
  • Strong understanding of software development best practices, version control (e.g., Bitbucket), and agile methodologies.
Cloud & AI Experience
  • Hands-on experience developing applications using cloud platforms such as Microsoft Azure and/or Amazon Web Services.
  • Familiarity with Generative AI concepts and experience integrating AI/ML models or APIs into applications.
Professional Skills
  • Excellent problem-solving skills and ability to work collaboratively in a team environment.
  • Clear and effective communication skills are necessary for collaborating with team members, presenting findings, and explaining complex AI concepts to non-technical stakeholders.

Factors To Help You Shine (Required Skills)
Azure AI & Generative AI
  • Proficiency in utilizing Microsoft Azure services, with a focus on AI and ML services such as Azure OpenAI, Azure AI Search, and Azure Vision.
  • Understanding of fundamental AI and RAG concepts for developing generative AI applications.
  • Commitment to ethical AI development, ensuring adherence to principles like fairness, transparency, accountability, and privacy in AI applications.
Python & API Development
  • Proficient in Python and familiar with current best practices and recent language features.
  • Experience with Python web frameworks for building APIs and backend services.
  • Strong experience in implementing and consuming RESTful web services.
DevOps & Software Engineering
  • Solid experience with software development best practices, including unit testing, continuous integration with tools like Jenkins, and version control with Bitbucket.
  • Experience with containerization and orchestration tools like Docker and OpenShift will be beneficial for deployment and scaling applications.
  • Familiarity with Azure DevOps for automating builds, testing, and deployment processes within Azure.
Security & Compliance
  • Understanding of compliance and security best practices within Azure, especially concerning handling sensitive data such as personal disability information.

Tekhire Solutions is a world-class technology focused on customer-driven solutions and has a deep dive knowledge of client requirements. Tekhire is best in connecting a bridge between highly skilled workers and the Fortune 500. Always thrives to be up with the technology trends, Innovation and transforms our trusted clients with certified and enterprise solutions that makes difference in the business.