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Senior Molecular Modeling Jobs in Renton, WA (NOW HIRING)

Direct single-cell Multiomics atlases and ML models for data-driven target prioritization across ... Present findings, strategies, and progress to senior leadership and other stakeholders. Minimum ...

The Group also has a rapidly developing presence in highly specialised and molecular clinical ... Coordinate with peers and Management in the design and creation of new offers, business models, and ...

Senior Molecular Modeling information

See Renton, WA salary details

$28.1K

$90.3K

$183.9K

How much do senior molecular modeling jobs pay per year?

As of Jun 12, 2026, the average yearly pay for senior molecular modeling in Renton, WA is $90,309.00, according to ZipRecruiter salary data. Most workers in this role earn between $46,700.00 and $115,900.00 per year, depending on experience, location, and employer.

What are some typical challenges faced by Senior Molecular Modeling professionals in cross-functional research teams?

Senior Molecular Modeling professionals often work closely with medicinal chemists, biologists, and data scientists, which can present challenges in translating complex computational findings into actionable insights for diverse teams. Balancing multiple project priorities and adapting modeling techniques to evolving research goals are common hurdles. Strong communication skills and a collaborative mindset are essential to bridge gaps between computational and experimental perspectives, ensuring that modeling results effectively guide experimental design and decision-making.

What does a Senior Molecular Modeler do?

A Senior Molecular Modeler is a specialist who uses computer simulations and theoretical chemistry techniques to study and predict the structure, properties, and behavior of molecules. They often work in pharmaceutical, biotechnology, or materials science settings, helping to design new drugs or materials by modeling interactions at the molecular level. Their responsibilities include running simulations, analyzing data, developing new modeling methods, and collaborating with experimental scientists to interpret results. Senior roles also typically involve project leadership and mentoring of junior colleagues.

What is the difference between Senior Molecular Modeling vs Molecular Dynamics Specialist?

AspectSenior Molecular ModelingMolecular Dynamics Specialist
Required CredentialsBachelor's/Master's in Chemistry, Biochemistry, or related fields; experience with modeling softwareBachelor's/Master's in Chemistry, Physics, or related fields; strong background in simulation techniques
Work EnvironmentResearch labs, pharmaceutical companies, biotech firmsResearch labs, pharmaceutical companies, biotech firms
Industry UsageDesigning molecular structures, drug discovery, material scienceRunning molecular dynamics simulations, analyzing simulation data
Common Search/ComparisonOften compared due to overlapping skills in modeling software and research goalsSpecializes in dynamic simulations, but overlaps with modeling tasks

While both roles involve computational chemistry and software tools, Senior Molecular Modeling focuses on creating and analyzing molecular structures, whereas Molecular Dynamics Specialists primarily run and interpret dynamic simulations to understand molecular behavior over time.

What are the key skills and qualifications needed to thrive as a Senior Molecular Modeler, and why are they important?

To thrive as a Senior Molecular Modeler, you need advanced knowledge in computational chemistry, molecular modeling, and structural biology, typically supported by a PhD in a related field. Proficiency with software tools like Schrödinger, MOE, AMBER, and programming languages such as Python or R is essential. Strong problem-solving, communication, and collaborative skills help you effectively interpret results and work within multidisciplinary teams. These skills and qualities are crucial for driving innovative drug discovery and accurately predicting molecular interactions.
What cities near Renton, WA are hiring for Senior Molecular Modeling jobs? Cities near Renton, WA with the most Senior Molecular Modeling job openings:

Director-Head of Molecular Profiling

Vrtx

Seattle, WA

$203K - $304K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 26 days ago


Job description

Job Description

Vertex Pharmaceuticals is seeking a highly motivated and innovative scientist to join our growing immunology research site in Seattle as the Director-Head of Immune Cell Profiling. This leadership role offers a unique opportunity to shape the future of immunology research by building and leading a cutting-edge Molecular Profiling team. The successful candidate will drive strategy, develop advanced research capabilities, and lead a team of scientists to uncover novel biological insights in order to identify, validate and prioritize therapeutic targets. In addition, they will develop and execute a strategy for reverse translation optimally enabling serial innovation for immunological indications in line with Vertex's strategic goals

The Molecular Profiling group will leverage state-of-the-art technologies, including spatial transcriptomics, single-cell RNA/ATAC sequencing, CYTOF, and state of the art proteomics. In close collaboration with the biomarker group the molecular profiling group forms the basis for biomarker discovery. In partnership with the Data & Computational Science group they will be integrating AI/ML-driven data analysis to advance our understanding of human biology and disease. The Head of Molecular Profiling will also play a pivotal role in fostering external collaborations with academic and industry partners to accelerate innovation and expand capabilities.

Key Responsibilities

  • Establish and lead Molecular Profiling capabilities at the Seattle research site, ensuring alignment with Vertex's strategic goals.
  • Develop and execute a strategic vision for the Molecular Profiling group, including identifying and prioritizing technology investments in collaboration with partner technology teams.
  • Build and lead a high-performing team of scientists, fostering a culture of innovation, collaboration, and scientific excellence.
  • Leverage clinical samples to generate novel biological insights and identify high-priority targets and pathways for further investigation in immunology indications.
  • Collaborate with the biomarker team to successfully execute on Vertex's biomarker strategy
  • Collaborate with Data and Computational Sciences to implement advanced AI/ML approaches for bridging clinical, experimental, and computational teams to nominate novel immunology targets.
  • Direct single-cell Multiomics atlases and ML models for data-driven target prioritization across autoimmune disease cohorts.
  • Serve as a key member of the Seattle Research leadership team, contributing to the overall strategy and success of the site.
  • Act as a leader on interdisciplinary project teams, driving scientific innovation and ensuring alignment with organizational goals.
  • Identify and establish external collaborations with academic institutions, biotech companies, and other organizations to enhance Molecular Profiling capabilities as opportunities arise.
  • Present findings, strategies, and progress to senior leadership and other stakeholders.

Minimum Qualifications

  • Ph.D. (or equivalent) in cellular biology, biochemistry, biophysics, or related disciplines with 10+ years of relevant post-doctoral experience
  • Proven expertise in spatial transcriptomics, CYTOF, single-cell sequencing, and proteomics.
  • Demonstrated experience in complex data analysis, including the application of AI/ML methods to derive novel biological insights.
  • Strong leadership skills with a track record of building and managing high-performing teams.
  • Excellent communication and presentation skills, with the ability to effectively collaborate across functional groups and present to senior leadership.
  • Self-motivated, organized, and adept at solving complex problems in a fast-paced, dynamic environment.
  • A passion for innovation and a commitment to transforming the lives of people with serious diseases, their families, and society.

Preferred Qualifications

  • Experience in immunology research and a deep understanding of immune system biology.
  • Experience leading cross-functional teams and managing external partnerships.

Pay Range:

$203,000 - $304,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com