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Senior Full Stack Software Engineer Jobs in Houston, TX

Next Step Systems

Full Stack Developer

Houston, TX · On-site

These Full Stack Developer openings are 12 month contracts. These positions are not open for ... Software Engineer, Software Developer, Programming, Programmer Analyst, Texas Recruiters ...

Worky

Software Engineer - Full Stack

Houston, TX · On-site

$110 - $160/hr

The Software Engineer - Full Stack drives measurable business impact by building scalable, secure, and high-performing digital platforms that accelerate product delivery, operational efficiency, and ...

Soni Resources

Full Stack Engineer

Houston, TX · On-site

$100/hr

Ideal Background: * 4-8 years of experience in full stack or software engineering, * Deep proficiency in JavaScript/TypeScript and one or more back-end languages (Python, Java, C#, Go). * Strong ...

CareOne

Junior Full Stack Software Developer

Houston, TX · On-site

$60K - $78K/yr

Collaborate with senior developers and internal teams to create scalable solutions * Participate in ... Gain hands-on experience with modern full-stack technologies * Work alongside experienced ...

CareOne

Junior Full Stack Software Developer

Houston, TX · On-site

$60K - $78K/yr

Collaborate with senior developers and internal teams to create scalable solutions * Participate in ... Gain hands-on experience with modern full-stack technologies * Work alongside experienced ...

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Senior Full Stack Software Engineer information

See Houston, TX salary details

$42.5K

$128.7K

$181.9K

How much do senior full stack software engineer jobs pay per year?

As of Sep 4, 2026, the average yearly pay for senior full stack software engineer in Houston, TX is $128,702.00, according to ZipRecruiter salary data. Most workers in this role earn between $106,000.00 and $150,900.00 per year, depending on experience, location, and employer.

What is a senior full stack software engineer?

A Senior Full Stack Software Engineer is an experienced developer responsible for designing, building, and maintaining both front-end and back-end systems in web or software applications. They work with a variety of technologies, frameworks, and databases to ensure seamless functionality across the entire software stack. In addition to coding, they often provide technical leadership, mentor junior developers, and contribute to architectural decisions. Their role requires strong problem-solving skills, an understanding of best practices, and the ability to collaborate with cross-functional teams to deliver high-quality software solutions.

What does a senior full stack software engineer do?

A typical day for a Senior Full Stack Software Engineer involves designing and implementing new features, reviewing and improving code, and collaborating with product managers, designers, and other developers to deliver project goals. You might split your time between writing code for both front-end and back-end systems, participating in daily stand-up meetings, and providing technical guidance to junior team members. The role often requires balancing hands-on development with architectural planning and problem-solving for complex technical challenges. You’ll also frequently interact with stakeholders to gather requirements and provide updates, ensuring alignment throughout the software development lifecycle.

What are the key skills and qualifications needed to thrive as a senior full stack software engineer?

To thrive as a Senior Full Stack Software Engineer, you need deep expertise in both front-end and back-end development, strong problem-solving abilities, and a solid foundation in computer science principles, typically demonstrated by a bachelor’s or master’s degree in a related field. Familiarity with frameworks and languages like React, Angular, Node.js, Python, and proficiency in using cloud platforms, version control systems like Git, and continuous integration tools is crucial, and relevant certifications are an advantage. Exceptional communication, leadership, and teamwork skills help you effectively coordinate with cross-functional teams and mentor junior engineers. These skills ensure you can deliver robust, scalable solutions while driving project success and fostering a collaborative development environment.

What are the most commonly searched types of Full Stack Software Engineer jobs in Houston, TX?

The most popular types of Full Stack Software Engineer jobs in Houston, TX are:

What are popular job titles related to Senior Full Stack Software Engineer jobs in Houston, TX?

For Senior Full Stack Software Engineer jobs in Houston, TX, the most frequently searched job titles are:

What job categories do people searching Senior Full Stack Software Engineer jobs in Houston, TX look for?

The top searched job categories for Senior Full Stack Software Engineer jobs in Houston, TX are:

What cities near Houston, TX are hiring for Senior Full Stack Software Engineer jobs?

Cities near Houston, TX with the most Senior Full Stack Software Engineer job openings:

Senior Full Stack Software Engineer jobs near you
Infographic showing various Senior Full Stack Software Engineer job openings in Houston, TX as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 9% Part Time, and 4% Contract. Highlights an 88% Physical, 4% Hybrid, and 8% Remote job distribution, with an average salary of $128,702 per year, or $61.9 per hour.

Senior Full Stack Developer (Agentic AI)

myDNA, Inc.

Houston, TX • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 8 days ago

Job description

Our Purpose
Our mission is to build a healthier and more connected world with precision health and genealogy services.
We empower individuals with actionable insights into their genetic makeup, fostering a deeper understanding of their ancestry, health, and wellness. By integrating the experience of Gene by Gene Laboratory Services, FamilyTreeDNA genealogy, and myDNA reporting services, we strive to deliver cutting-edge genetic testing and personalized solutions that inspire informed decisions and enhance quality of life. Our team is dedicated to advancing the field of genomics through innovation, research, and a commitment to excellence.
Our Values
All employees are expected to demonstrate our values of Innovate, One Team, and Integrity when carrying out the accountabilities and responsibilities of their role. This how we show up every day for ourselves, our colleagues and our customers and strategic partners to deliver our vision and strategic goals.
Position Overview
We are seeking a Senior Full Stack Developer (Agentic AI) to join our engineering team. In this hands-on senior role, you will be responsible for building, maintaining, and scaling production-grade full-stack applications that integrate agentic AI capabilities. You will leverage modern AI-assisted development tools to dramatically accelerate delivery and elevate code quality, while maintaining deep hands-on oversight to ensure our solutions remain reliable, maintainable, and implementable. Your focus will be on the practical implementation, stability, and state management of AI agents within our existing product ecosystem, ensuring they operate reliably in a regulated environment. This includes implementing robust guardrails, security protocols, and testing/auditing mechanisms to ensure safe and predictable AI agent behavior. As a senior individual contributor, you will own features from local development through to automated CI/CD deployment and infrastructure management.
Accountabilities and Responsibilities
  • Design, build, and maintain scalable, robust full-stack features using C#, .NET, and modern frontend frameworks (Angular or React).
  • Integrate agentic AI workflows into production, building reliable state management and execution patterns to ensure agent consistency across complex, multi-step tasks.
  • Write and tune complex SQL queries and design database schemas across MS SQL Server and PostgreSQL to support traditional and AI-driven features.
  • Manage and scale AWS cloud infrastructure using Infrastructure-as-Code (Terraform or CloudFormation), while maintaining automated CI/CD pipelines for rapid, compliant production deployments.
  • Implement comprehensive observability and monitoring for traditional application logic and agentic AI components to ensure system uptime, performance, and reliability.
  • Participate in peer code reviews, mentor junior team members, establish shared engineering standards, and drive continuous improvement in an iterative Agile/Scrum environment.

Position Requirements
Experience, Skills & Knowledge
  • 8+ years of professional software engineering experience with deep expertise in C#, .NET Core, and modern frontend frameworks (Angular/React).
  • Proven experience integrating AI models and agentic workflows into production applications, with a strong focus on building stable, predictable systems in regulated environments.
  • Production experience with AWS cloud infrastructure (Lambda, RDS, Bedrock) managed via Infrastructure-as-Code (Terraform/CloudFormation).
  • Strong testing discipline: unit, integration, and contract testing, plus the ability to build evaluation harnesses for AI features.
  • Excellent written and verbal communication; ability to explain technical and AI-related tradeoffs to non-technical, legal, and compliance stakeholders.
  • Mentorship & Collaboration: A desire to mentor junior team members and foster a collaborative engineering culture through effective peer code reviews.
  • Agile Proficiency: Comfortable working in an iterative, Agile/Scrum environment with a focus on delivering incremental value.
  • Learning Agility: A proactive learner who stays current with the rapidly evolving AI landscape and contributes to team knowledge sharing.
  • Problem-Solving: Exceptional analytical skills, with a track record of diagnosing and resolving complex, production-level performance and stability issues.

Compliance, Governance & Technologies
  • Demonstrated success in implementing safety guardrails, security protocols, and auditability for AI-driven features.
  • Proficiency in leveraging AI-assisted development tools (e.g., Claude Code, GitHub Copilot, Cursor) to accelerate delivery, improve code quality, and maintain high standards of reliability and maintainability.
  • Demonstrable experience delivering software within highly regulated, audit-ready environments (e.g., HIPAA, CAP/CLIA, or similar compliance frameworks).
  • Experience with AI orchestration patterns (e.g., RAG pipelines, agentic state management) and frameworks (e.g., LangChain, Semantic Kernel).
  • Experience implementing custom observability and evaluation patterns, such as leveraging OpenTelemetry for distributed tracing, monitoring model latency/hallucinations, and building automated validation harnesses.

Education
  • Bachelor's degree in Computer Science or related field.

Why Join Us
At Gene by Gene, you'll join a mission-driven team advancing the science of genetics and discovery. You'll have the opportunity to shape meaningful campaigns, tell compelling brand stories, and collaborate with talented professionals who share your passion for creativity, curiosity, and impact.
Comprehensive Benefits
  • Medical & Health Savings: Choice of 3 medical tiers generously sponsored by the company, with a monthly $50-$100 employer HSA contribution based on plan type and dependent level.
  • 100% Covered Dental & Vision: No premium costs for employees or dependents.
  • 401(k) Matching: Generous 50% company match up to 6% of annual base salary.
  • Diverse PTO Framework: Structured time off incorporating vacation, sick leave, mental health days, personal days, company holidays, and a flexible floating holiday.
  • Income Protection & Family Leave: Full company sponsorship of Short-Term and Long-Term Disability (STD/LTD) alongside Paid Family Leave offerings.

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