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Senior Director Statistical Programming Jobs in Boston, MA

Dyne Tx

Senior Director, Biostatistics

Waltham, MA · On-site

$250 - $290/hr

Role Summary The Senior Director, Biostatistics provides strategic, technical, and operational ... Management, Statistical Programming, Translational Medicine, Program Management, and other ...

Treeline Biosciences

Director, Biostatistics

Watertown, MA · On-site

$226K - $257K/yr

Director of Biostatistics The Director of Biostatistics will lead the statistical strategy, design ... Analysis & Programming: Program, validate, and perform statistical analyses for trial data cuts ...

Treeline Biosciences

Director, Biostatistics

Watertown, MA · On-site

$226K - $257K/yr

Director of Biostatistics The Director of Biostatistics will lead the statistical strategy, design ... Analysis & Programming: Program, validate, and perform statistical analyses for trial data cuts ...

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All JobsStatistical Programming JobsSenior Director Statistical Programming JobsSenior Director Statistical Programming Jobs in Boston, MA

Senior Director Statistical Programming information

See Boston, MA salary details

$26.1K

$107.6K

$181.4K

How much do senior director statistical programming jobs pay per year?

As of Aug 12, 2026, the average yearly pay for senior director statistical programming in Boston, MA is $107,563.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $116,200.00 per year, depending on experience, location, and employer.

What is the difference between Senior Director Statistical Programming vs Statistical Programming Manager?

AspectSenior Director Statistical ProgrammingStatistical Programming Manager
CredentialsAdvanced degree (MS/PhD), extensive experience in statistical programmingBachelor's or Master's degree, several years of experience
Work EnvironmentStrategic leadership, cross-functional collaboration, high-level decision makingTeam management, project oversight, technical execution
Employer & Industry UsagePharmaceuticals, biotech, clinical research organizationsPharmaceuticals, biotech, clinical research organizations
Search & Comparison IntentUnderstanding senior leadership roles in statistical programmingManaging statistical programming teams and projects

The Senior Director Statistical Programming typically holds a strategic leadership role with extensive experience and oversees multiple teams or departments. In contrast, the Statistical Programming Manager focuses on managing day-to-day project execution and team management. Both roles are vital in clinical research, but the senior director operates at a higher strategic level.

What are the most commonly searched types of Senior Statistical Programming jobs in Boston, MA? The most popular types of Senior Statistical Programming jobs in Boston, MA are:
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What cities near Boston, MA are hiring for Senior Director Statistical Programming jobs? Cities near Boston, MA with the most Senior Director Statistical Programming job openings:
Senior Director Statistical Programming jobs near you

Director/ Senior Director, Biostatistics

Cogent Biosciences

Waltham, MA

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 20 days ago

Job description

Who We Are:

Cogent Biosciences is a publicly traded biotechnology company focused on developing novel precision therapies to treat a broad range of patients with unmet medical needs. Cogent's lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V. KIT D816V is responsible for driving a rare and serious condition called Systemic Mastocytosis, and exon 17 mutations are also found in patients with gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling. Bezuclastinib has exhibited promising initial data across all three trials: APEX in AdvSM, SUMMIT in NonAdvSM and PEAK in GIST, including an encouraging safety profile across 600+ patients in single agent and combination dosing. 

The Role: The Director/Senior Director of Biostatistics provides scientific and strategic guidance for one or more clinical development projects. In this role, you will ensure the design, analysis, and interpretation of study data meet the highest standards of scientific rigor and regulatory compliance. You will collaborate closely with partner functions-including Medical, Clinical Science, Clinical Operations, Data Management, and Statistical Programming-to support study objectives, contribute to regulatory submissions, and help drive the success of clinical development programs. This position reports to the VP, Biometrics. 

Responsibilities:

  • Serve as statistical lead for assigned oncology clinical programs, providing strategic and hands-on statistical leadership from early development through pivotal trials and regulatory submissions.
  • Provide statistical input into clinical development strategy, protocol design, endpoint selection, estimands, sample size calculations, interim analyses, and adaptive designs.
  • Develop and review statistical analysis plans, clinical study reports, regulatory documents, and responses to health authority questions.
  • Support NDA/BLA submissions and regulatory interactions with statistical expertise.
  • Oversee statistical activities performed by CROs and external consultants, ensuring high-quality and timely delivery of statistical outputs.
  • Collaborate closely with Clinical Development, Regulatory Affairs, Data Management, Clinical Operations, and Statistical Programming teams.
  • Contribute to building and enhancing Biometrics capabilities, processes, and best practices in a growing biotech environment.

Qualifications:

  • Ph.D. in Biostatistics or Statistics with at least 8+ years of experience in pharmaceutical or biotechnology industry; or MS with at least 10+ years of relevant experience.
  • Strong oncology clinical development experience preferred.
  • Experience as the lead statistician for one or more clinical development projects, including pivotal studies.
  • Experience supporting regulatory submissions (NDA/BLA/MAA) and interactions with health authorities.
  • Strong understanding of ICH GCP and general knowledge of industry practices and standards.
  • Proficiency in SAS programming and other statistical software, including EAST, nQuery, or PASS.
  • Experience with CDISC standards, including SDTM, ADaM, CDASH.
  • Excellent communication, leadership, and cross-functional collaboration skills.

Salary Range:

  • Director: $225,000 - $265,000
  • Sr. Director: $255,000 - $300,000
Target Bonus: Director: 20%, Sr. Director: 25%
 
Exact compensation will vary based on skills, experience, and location.
Our Locations

Waltham, MA: Our headquarters is located in the Greater Boston life sciences community, with an open, collaborative office environment designed to support teamwork and connection. Employees benefit from convenient on-site amenities, including free on-site parking and gym facilities in the building. 

Boulder, CO: Our Boulder location is home to Cogent's discovery research organization and a key scientific hub with strong leadership based on site. Situated in the greater Denver-Boulder biopharmaceutical corridor, this office plays a central role in advancing our discovery efforts and pipeline. 

Our Offer To You 

At Cogent Biosciences, we offer a competitive salary, bonus, and ongoing stock awards, alongside a benefits package that sets us apart. We cover 100% of medical, dental, and vision premiums for you and your family, and help reduce out-of-pocket costs by funding up to 75% of in-network deductibles. Our benefits also include a 401(k) match with immediate vesting, generous paid time off, 12 weeks of fully paid parental leave, paid family and medical leave for all employees regardless of location, and company-paid short-term disability coverage for up to 20 weeks. Additional perks like wellness programs, tuition reimbursement, and inclusive family-forming support help you thrive at work and beyond. 

We are proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability, or any other status protected under federal, state, or local law. All employment is decided on the basis of qualifications, merit, and business need. 

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