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Senior Director Statistical Programming Jobs in Boston, MA

Biogen

Sr. Analyst, Statistical Programming

Cambridge, MA · On-site

$95K - $130K/yr

About this role The Senior Analyst, Statistical Programming leads and oversees statistical programming activities both internally and externally through vendors in the application of data standards ...

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All JobsStatistical Programming JobsSenior Director Statistical Programming JobsSenior Director Statistical Programming Jobs in Boston, MA

Senior Director Statistical Programming information

See Boston, MA salary details

$26.1K

$107.6K

$181.4K

How much do senior director statistical programming jobs pay per year?

As of Sep 2, 2026, the average yearly pay for senior director statistical programming in Boston, MA is $107,563.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,500.00 and $116,200.00 per year, depending on experience, location, and employer.

What is the difference between Senior Director Statistical Programming vs Statistical Programming Manager?

AspectSenior Director Statistical ProgrammingStatistical Programming Manager
CredentialsAdvanced degree (MS/PhD), extensive experience in statistical programmingBachelor's or Master's degree, several years of experience
Work EnvironmentStrategic leadership, cross-functional collaboration, high-level decision makingTeam management, project oversight, technical execution
Employer & Industry UsagePharmaceuticals, biotech, clinical research organizationsPharmaceuticals, biotech, clinical research organizations
Search & Comparison IntentUnderstanding senior leadership roles in statistical programmingManaging statistical programming teams and projects

The Senior Director Statistical Programming typically holds a strategic leadership role with extensive experience and oversees multiple teams or departments. In contrast, the Statistical Programming Manager focuses on managing day-to-day project execution and team management. Both roles are vital in clinical research, but the senior director operates at a higher strategic level.

What are the most commonly searched types of Senior Statistical Programming jobs in Boston, MA?

The most popular types of Senior Statistical Programming jobs in Boston, MA are:

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For Senior Director Statistical Programming jobs in Boston, MA, the most frequently searched job titles are:

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Senior Director Statistical Programming jobs near you

Associate Director, Statistical Programming

MBX Biosciences

Burlington, MA • On-site

Full-time

Posted 17 days ago

Job description

Working with Us
MBX Biosciences is a clinical-stage biopharmaceutical company headquartered in Carmel, Indiana, with a secondary office in Burlington, MA. Our mission is to transform the lives of people impacted by endocrine and metabolic disorders through our novel precision peptides.
Leveraging our proprietary Precision Endocrine Peptides (PEPs)™ platform, we are pioneering technology designed to overcome key limitations of existing therapies and enhance efficacy, tolerability, safety and convenience. Our team is advancing a pipeline of novel candidates with clinically validated targets, established endpoints for regulatory approval, and strong market potential.
Our pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism, currently preparing for Phase 3 development, and a growing obesity portfolio that includes MBX 4291 in Phase 1 development, MBX 5765, a next-generation amycretin prodrug designed for once-monthly dosing, as well as MBX 6180, a GLP/GIP/GCGR triple agonist prodrug for once monthly dosing; all of which optimize our PEP platform.
If you're passionate about advancing innovative treatments for patients and shaping the future of precision peptide therapeutics, this is your chance to make a real impact alongside a fast-paced, growing, mission-driven team. To learn more, visit our website mbxbio.com and follow us on LinkedIn.
Position Summary
MBX is seeking an Associate Director, Statistical Programming to lead and contribute to statistical programming and analysis of clinical trial data. This role is integral to the design, execution, and interpretation of analyses for clinical trials and related research activities. The Associate Director will ensure the quality and accuracy of statistical deliverables, oversee external vendor performance, and contribute to internal process improvements, including maintaining and expanding SAS macros, R workflows, and clinical data repositories.
What You'll Do
  • Oversee and execute statistical programming deliverables for planned analyses, including study monitoring, data reviews, clinical study reports, data integrations, and rapid responses to regulatory queries across multiple compounds and studies.
  • Lead global submission activities, acting as a programming functional and technical expert to support submission strategy planning and regulatory communications; ensure all programming deliverables meet timelines, quality standards, and regulatory expectations (eg, ICH, FDA, EMA).
  • Manage CROs and contractors to ensure compliance, high-quality deliverables, adherence to timelines, and budget alignment.
  • Develop and validate reproducible, well-documented statistical programs to produce outputs for integrated scientific reports of clinical trial results, ensuring adherence to protocols and Statistical Analysis Plans (SAPs), and regulatory reporting conventions.
  • Maintain and enhance the internal SAS macro library and database.
  • Provide statistical programming input for SAPs, publications, scientific presentations, regulatory submissions, and promotional materials.
  • Review Case Report Forms (CRFs), CRF annotations, SAPs, Table, Listing, and Figure (TLF) shells, TLF outputs, dataset specifications (SDTM and ADaM).
  • Serve as a lead for statistical programming within study teams, effectively communicating statistical and programming issues to development teams.
  • Contribute to the development of programming standards, macros, SOPs, and process improvements within the Biometrics function
  • Other responsibilities as assigned.

What You Bring
  • 8+years of statistical programming experience in the biotech or pharmaceutical industry, with a preference for expertise in endocrine and metabolic disorders.
  • Advanced degree (PhD, MS, etc.) in life sciences, biostatistics, mathematics, computer science, or a related field preferred.
  • Proficient in SAS programming (e.g., Base SAS, SAS/Stat, SAS/Graph, SAS macros, ODS) with a solid understanding of database systems
  • Experience with R and Python preferred for advanced data visualization and analysis.
  • Extensive experience with CDISC standards (SDTM, ADaM, define.xml) and electronic submissions (eSub) under eCTD specifications.
  • Proven ability to lead programming activities and provide oversight of CRO deliverables.
  • Strong analytical, organizational, and communication skills, with a keen eye for detail and the ability to manage multiple priorities in a dynamic, fast-paced environment.
  • Demonstrated leadership in cross-functional teams, experience with global submissions, and knowledge of database management.

Travel & In Office Presence
You will be expected to travel periodically based on the needs of the business, including attendance at Together Weeks, Together Days, and functional meetings as requested by the team. Employees are expected to work on hybrid schedules, consistent with local office practices and the terms of the companies in office policy as in effect from time to time.
EEO Statement:
MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.

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