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Senior Director Quality Control Jobs (NOW HIRING)

Nurix

Senior Director, Quality Control

Brisbane, CA · On-site

$280K - $319K/yr

Senior Director, Quality Control Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation ...

Cellectis

Director, Quality Control

Raleigh, NC · On-site

POSITION SUMMARY The Director, Quality Control provides strategic and operational leadership for all Quality Control (QC) activities supporting drug substance (DS) and dug product (DP) manufacturing ...

KBI Biopharma, Inc.

Sr. Director, Quality

Durham, NC · On-site

Quality Control The Senior Director of Quality, Quality Site Head is accountable for QC Analytical and QC Microbiology. He/she is responsible for oversight of QC Analytical testing. He/she is ...

Omeros

Director, Quality Control

Seattle, WA

The Director, Quality Control will provide strategic leadership in managing a growing team of scientists responsible for QC-related activities and operations. This individual will be responsible for ...

KBI Biopharma, Inc.

Sr. Director, Quality

Durham, NC · On-site

Quality Control The Senior Director of Quality, Quality Site Head is accountable for QC Analytical and QC Microbiology. He/she is responsible for oversight of QC Analytical testing. He/she is ...

Revlon Corporate

Director, Quality Control

Oxford, NC · On-site

Revlon is seeking a Director, Quality Control to lead Quality Control laboratory operations at the Oxford, NC manufacturing site. This role is responsible for ensuring timely, accurate, compliant ...

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As of Sep 14, 2026, the average yearly pay for senior director quality control in the United States is $125,600.00, according to ZipRecruiter salary data. Most workers in this role earn between $91,000.00 and $151,000.00 per year, depending on experience, location, and employer.

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Infographic showing various Senior Director Quality Control job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 80% Full Time, 14% Part Time, 4% Contract, and 1% Nights. Highlights an 90% Physical, 1% Hybrid, and 9% Remote job distribution, with an average salary of $125,600 per year, or $60.4 per hour.

Senior Director, Quality Control

Brisbane, CA • On-site

Nurix
See more jobs at Nurixexternal

$280K - $319K/yr

Full-time

Posted 7 days ago

Job description

Senior Director, Quality Control
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix's dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a new script to outmatch disease.
Position Description
Nurix Therapeutics is seeking an experienced Senior Director, Quality Control to join the Analytical Development and Quality Control group. This individual will establish and lead a QC operational function, establishing operations, systems, and a team to support programs from CMC development through commercial manufacturing.
The ideal candidate brings deep expertise in small molecule QC, strong regulatory acumen, and proven experience managing external CDMO and CTL relationships. This role will represent QC in health authority inspections and audits, and will work cross-functionally with Quality, Analytical Development, and Manufacturing to ensure product quality and patient safety across the portfolio.
Key responsibilities
  • Build and lead the QC function: Establish QC systems and infrastructure; recruit, manage, and mentor internal QC staff and contractors
  • Set QC strategy across the product lifecycle: Define and execute QC strategy spanning CMC development through commercial programs, ensuring alignment with company milestones and submission timelines
  • Oversee QC operations internally and externally: Direct method validation, release and stability testing, data review, deviations, investigations, change control, and CAPA internally and at CDMOs, and CTLs
  • Identify and manage quality risk: Proactively identify, assess, and escalate risks related to patient safety, product quality, shelf life, supply continuity, or GMP compliance; drive risk mitigation strategies in partnership with Analytical Development, Quality, and Manufacturing functions
  • Lead QC through audits and inspections: Serve as QC lead during health authority inspections and internal audits; collaborate with Quality to conduct audits of GMP manufacturing and testing sites, including CDMOs and CTLs
  • Support regulatory submissions and health authority interactions: Contribute to global regulatory filings; collaborate on responses to health authority information requests, regulatory commitments, and post-approval changes
  • Direct stability programs: Develop and execute stability strategy in collaboration with Analytical Development leads, ensuring alignment with ICH guidelines and regional regulatory requirements
  • Manage reference materials and retains: Oversee qualification and inventory of reference standards; develop sampling plans and manage sample retain programs
  • Drive continuous improvement: Identify and implement process improvements, data integrity enhancements, and quality system upgrades (e.g., eQMS) to support a scalable, inspection-ready QC organization
  • Travel up to 15% to CDMO, CTL, and manufacturing sites and supplier and scientific conferences

Qualifications
  • Advanced degree in Chemistry, Pharmaceutics, Chemical Engineering, or related discipline. BS/MS with 16+ years of relevant experience, or PhD with 14+ years of relevant experience
  • 5+ years in a QC leadership or management role, with demonstrated ability to build and mentor teams
  • Deep experience in small molecule pharmaceutical development, including method lifecycle management and oversight of validation, release, and stability operations
  • Proven experience managing external manufacturing and testing operations at CDMOs and CTLs
  • Expertise with analytical methods such as HPLC, GC, dissolution, and microbiological testing
  • Direct experience leading through health authority inspections and internal audits and conducting audits of manufacturing and testing sites.
  • Deep working knowledge of cGMP, ICH guidelines, and USP/EP/JP compendial standards
  • Experience contributing to global regulatory filings and health authority correspondence (e.g., responses to information requests, post-approval changes)
  • Strong interpersonal and cross-functional collaboration skills, with the ability to influence and build consensus across Quality, Supply Chain, Analytical Development, and Manufacturing functions

Fit with Nurix Culture and Values
  • Strong team orientation; highly collaborative
  • Solutions and results-oriented focus
  • Hands-on approach; resourceful and open to diverse points of view

Salary Range: $280,200 - $319,800
Location: Woodlands TX or Brisbane, CA - Onsite

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