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Senior Biotech Software Engineer Jobs (NOW HIRING)

BigHat Biosciences

Senior Software Engineer

San Mateo, CA · On-site

$140K - $184K/yr

Senior Software Engineer Department: Engineering Employment Type: Full Time Location: San Mateo, CA ... Candidates with prior experience in biotech, life sciences, or scientific software may be ...

BigHat Biosciences

Senior Software Engineer

San Mateo, CA

$139K - $183K/yr

BigHat Biosciences is looking for a Senior Software Engineer to join our engineering team. This ... Candidates with prior experience in biotech, life sciences, or scientific software may be ...

Spire

Senior Backend Software Engineer

Boulder, CO · Hybrid

$127K - $167K/yr

About the Role Spire is looking for a Senior Software Engineer to help design, build, and improve ... Experience working in aerospace, scientific computing, biotech, telecommunications, robotics, or ...

Natera

OR · On-site

$122K - $161K/yr

Natera is seeking a skilled, self-motivated, and hands-on Senior Software Engineer to join a software development team in the Oncology domain within a fast-growing biotech company. You will play a ...

Spire

Senior Backend Software Engineer

Boulder, CO · Hybrid

$130K - $171K/yr

About the Role Spire is looking for a Senior Software Engineer to help design, build, and improve ... Experience working in aerospace, scientific computing, biotech, telecommunications, robotics, or ...

STARLIMS

Senior Software Engineer IV

Hollywood, FL · On-site

$112K - $148K/yr

Senior Software Engineer IV - STARLIMS Remote, U.S.| Full Time | R&D STARLIMS provides leading ... biotech, life sciences, food & beverage, manufacturing, petrochemical refineries and oil & gas ...

BigHat Biosciences

Senior Software Engineer

San Mateo, CA · On-site

$139K - $184K/yr

Job Summary : BigHat Biosciences is looking for a Senior Software Engineer to join their ... biotech, life sciences, laboratory environments, or scientific software, where domain knowledge ...

Spire

Senior Backend Software Engineer

Boulder, CO · On-site

$130K - $171K/yr

About the Role Spire is looking for a Senior Software Engineer to help design, build, and improve ... Experience working in aerospace, scientific computing, biotech, telecommunications, robotics, or ...

Mithrl

Senior Software Engineer

San Francisco, CA · On-site

$175K - $220K/yr

... performance software used daily by world-class researchers. As a senior engineer, you will be ... Exposure to biotech, life sciences, or R&D workflows WHAT YOU WILL LOVE AT MITHRL * High ownership ...

Mithrl

Senior Software Engineer

San Francisco, CA · On-site

$175K - $220K/yr

... performance software used daily by world-class researchers. As a senior engineer, you will be ... Exposure to biotech, life sciences, or R&D workflows WHAT YOU WILL LOVE AT MITHRL * High ownership ...

GenScript/ProBio

Sr. Software Engineer

Redmond, WA · On-site

$150K - $170K/yr

About GenScript Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation ... Act as SME for software architecture: document APIs, mentor junior engineers, and align technical ...

GenScript/ProBio

Sr. Software Engineer

Redmond, WA · On-site

$150K - $170K/yr

About GenScript Founded in 2002 in New Jersey, GenScript Biotech Corporation accelerates innovation ... Act as SME for software architecture: document APIs, mentor junior engineers, and align technical ...

Kemin

Senior Software Engineer

Des Moines, IA · Hybrid

$119K - $157K/yr

As a Senior Software Engineer, you will serve as the highest-level engineering execution ... We are a privately held, family-owned-and-operated global biotechnology company driven by curiosity ...

Kemin

Senior Software Engineer

Des Moines, IA · On-site

$119K - $157K/yr

As a Senior Software Engineer, you will serve as the highest-level engineering execution ... We are a privately held, family-owned-and-operated global biotechnology company driven by curiosity ...

Kemin

Senior Software Engineer

Des Moines, IA · Hybrid

$119K - $157K/yr

As a Senior Software Engineer, you will serve as the highest-level engineering execution ... We are a privately held, family-owned-and-operated global biotechnology company driven by curiosity ...

ETAP Software

Senior Software Engineer

Irvine, CA · On-site

$129K - $171K/yr

They are seeking a Senior Software Engineer to maintain and enhance software that supports state estimation and virtual metering for complex electrical networks, as well as develop REST APIs and ...

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Senior Biotech Software Engineer information

See salary details

$75.5K

$143.3K

$192K

How much do senior biotech software engineer jobs pay per year?

As of Jul 29, 2026, the average yearly pay for senior biotech software engineer in the United States is $143,292.00, according to ZipRecruiter salary data. Most workers in this role earn between $122,500.00 and $161,500.00 per year, depending on experience, location, and employer.

What is the difference between Senior Biotech Software Engineer vs Biotech Software Developer?

AspectSenior Biotech Software EngineerBiotech Software Developer
CredentialsBachelor's or Master's in Bioinformatics, Software Engineering, or related fields; experience preferredBachelor's or higher in Computer Science, Bioinformatics, or related fields; entry to mid-level experience
Work EnvironmentResearch labs, biotech companies, pharmaceutical firmsSoftware development teams within biotech or pharma companies
Industry UsageDesigns and develops biotech-specific software, algorithms, and data analysis toolsDevelops software applications for biotech research and data management

The main difference is experience level and responsibility. Senior Biotech Software Engineers typically lead projects, have more advanced skills, and handle complex biotech software solutions, while Biotech Software Developers focus on coding and supporting software development under supervision. Both roles are essential in biotech industries, but the senior role involves greater expertise and leadership.

More about Senior Biotech Software Engineer jobs
What cities are hiring for Senior Biotech Software Engineer jobs? Cities with the most Senior Biotech Software Engineer job openings:
What are the most commonly searched types of Biotech Software Engineer jobs? The most popular types of Biotech Software Engineer jobs are:
What states have the most Senior Biotech Software Engineer jobs? States with the most job openings for Senior Biotech Software Engineer jobs include:
What job categories do people searching Senior Biotech Software Engineer jobs look for? The top searched job categories for Senior Biotech Software Engineer jobs are:
Senior Biotech Software Engineer jobs near you
Infographic showing various Senior Biotech Software Engineer job openings in the United States as of July 2026, with employment types broken down into 91% Full Time, 1% Part Time, 1% Temporary, and 7% Contract. Highlights an 81% Physical, 3% Hybrid, and 16% Remote job distribution, with an average salary of $143,292 per year, or $68.9 per hour.

Senior Software Engineer

BigHat Biosciences

San Mateo, CA • On-site

$140K - $184K/yr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 6 days ago

Job description

Senior Software Engineer
Department: Engineering
Employment Type: Full Time
Location: San Mateo, CA
Description
The role: BigHat Biosciences is looking for a Senior Software Engineer to join our engineering team. This role is for experienced engineers ready to own a significant area of our platform as a subject-matter expert, lead epics end-to-end, and shape the architecture and engineering practices that support the design, build, and testing of therapeutic antibodies at scale. You will work closely with engineers, product partners, and laboratory scientists to build and evolve the internal software systems at the center of our science.
This role is leveled as Senior Software Engineer I. At this level, you operate as a subject-matter expert in your area, working with a high degree of independence and regularly leading epics. Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience.
*At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.
Key Responsibilities
  • Lead projects end-to-end, from PRD through implementation, testing, release, and validation against the customer success metric.
  • Own one or more major areas of BigHat's internally developed, cloud-based platform as a subject-matter expert, and serve as a cross-team and cross-org resource for those areas.
  • Take on net-new, 0-to-1 work from specification, designing interactions between features and the infrastructure that supports them, and producing novel solutions where existing patterns fall short.
  • Collaborate with, and increasingly manage, the relationship with scientists and product owners to translate real-world lab workflows into reliable software, and to iterate on success metrics.
  • Operate and run engineering processes: PRD reviews, stand-ups, PR approvals, and other team ceremonies.
  • Own the quality and outcomes of your work and your epics, including debugging, test failures, and production issues, anticipating next steps and owning the trajectory of major features.
  • Drive technical depth across the codebase, infrastructure, and systems, and actively improve the design and architectural principles the team works within.
  • Design and build high-quality software across front-end (UI/UX) and back-end systems, with system-level expertise in the databases, AWS services, runtimes, and processes that underpin them.
  • Lead and review technical designs and PRDs; contribute architectural direction and surface risks and tradeoffs early.
  • Write, maintain, and raise the bar on automated testing to ensure correctness, reliability, and maintainability.
  • Run code reviews as a routine approver, providing thoughtful, high-leverage feedback that develops other engineers.
  • Diagnose and resolve complex issues across production and development environments, including across system and environment boundaries.
  • Improve internal engineering practices, documentation, tooling, and architecture; help set and transmit appropriate urgency in partnership with engineering leaders.

Skills Knowledge and Expertise
  • You have a track record of owning features and epics end to end in a production software environment.
  • You are an SME in at least one significant technical area and are reaching to master new ones.
  • You work highly independently and initiate the collaborations needed to deliver work that bridges many parts of the codebase.
  • You balance development, architecture, and process effectively, and help the team prioritize where effort yields the most impact.
  • You communicate clearly about progress, risks, and tradeoffs, and your own outcomes, following issues through to resolution and validating that you've met the customer's needs.
  • You are motivated by building software that supports real users doing complex, high-stakes scientific work.
  • You adapt well as priorities and focus areas shift, and you collaborate effectively with engineers inside and outside your direct team.
  • 7+ years of professional software engineering experience building and owning production systems, including demonstrated end-to-end ownership of features or epics, OR
  • 5+ years of professional software engineering experience with prior experience in biotech, life sciences, laboratory environments, or scientific software, where domain knowledge meaningfully accelerates impact.

Depth in several of the following, with the ability to make and improve system- and architecture-level decisions:
  • TypeScript, React, Material-UI, Vega
  • Python 3, SQLAlchemy
  • RESTful API design
  • AWS (CDK, Lambda, Step Functions, ECS/Batch, Fargate, API Gateway, Athena)
  • Relational databases (e.g., PostgreSQL), including schema and query design
  • Pandas
  • PyTorch or other ML frameworks (nice to have, not required)

Total Rewards
The salary estimated for this position is $198,00 - $215,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave

Apply