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Senior Bioinformatics Software Engineer Jobs in Springfield, MO

Senior Systems Engineer

Springfield, MO · On-site

$98K - $134K/yr

The Senior Platform Engineer designs, implements, and supports enterprise infrastructure solutions ... Troubleshoot and resolve complex infrastructure, operating system, hardware, software, and ...

Senior Structural Project Manager

Springfield, MO · On-site

$85K - $116K/yr

Structural Engineer IV / Senior Structural Engineer (Buildings) Location: Springfield, MO or Fort ... Strong knowledge of structural analysis and design software such as ETABS, RAM, RISA, SAP2000 ...

Senior Structural Project Manager

Springfield, MO · On-site

$85K - $116K/yr

Structural Engineer IV / Senior Structural Engineer (Buildings) Location: Springfield, MO or Fort ... Strong knowledge of structural analysis and design software such as ETABS, RAM, RISA, SAP2000 ...

Senior Structural Project Manager

Springfield, MO · On-site

$85K - $116K/yr

Structural Engineer IV / Senior Structural Engineer (Buildings) Location: Springfield, MO or Fort ... Strong knowledge of structural analysis and design software such as ETABS, RAM, RISA, SAP2000 ...

DevOps Engineer, Sr.

Springfield, MO · On-site

$130 - $170/hr

... Engineer, Sr. on a 10 year contract providing User Facing and Data Center Services supporting an ... Applies configuration management disciplines to maintain software revisions, security patches ...

Civil Engineer

Springfield, MO · On-site

$60K - $90K/yr

Wilson & Company is seeking a Civil Engineer with experience in freight rail, rail track, terminal ... senior-level roles. * Proficiency with CADD and design software such as MicroStation, OpenRail ...

Showing results 41-60

Senior Bioinformatics Software Engineer information

See Springfield, MO salary details

$76.9K

$93K

$108.7K

How much do senior bioinformatics software engineer jobs pay per year?

As of Sep 4, 2026, the average yearly pay for senior bioinformatics software engineer in Springfield, MO is $93,029.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,000.00 and $100,100.00 per year, depending on experience, location, and employer.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Springfield, MO?

The most popular types of Bioinformatics Software Engineer jobs in Springfield, MO are:

What cities near Springfield, MO are hiring for Senior Bioinformatics Software Engineer jobs?

Cities near Springfield, MO with the most Senior Bioinformatics Software Engineer job openings:

Infographic showing various Senior Bioinformatics Software Engineer job openings in Springfield, MO as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $93,029 per year, or $44.7 per hour.

Senior Systems Engineer

O'Reilly Auto Parts

Springfield, MO • On-site

$98K - $134K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 29 days ago


O'Reilly Auto Parts rating

5.3

Company rating: 5.3 out of 10

Based on 1,907 frontline employees who took The Breakroom Quiz

557th of 739 rated retailers


Job description

The Senior Platform Engineer designs, implements, and supports enterprise infrastructure solutions with a primary focus on the IBM i platform. This role partners with business and IT teams to evaluate technical requirements, develop scalable and secure infrastructure solutions, and ensures the performance of enterprise systems. They serve as a technical subject matter expert, resolves complex infrastructure issues, and drives continuous improvement through proactive planning and modernization.
ESSENTIAL JOB FUNCTIONS
Design, implement, maintain, and support enterprise infrastructure solutions with a primary focus on the IBM i platform.
Gather, analyze, and document business and technical requirements to develop infrastructure solutions that align with organizational needs.
Evaluate current-state environments and recommend future-state architecture with implementation plans that improve overall system operations.
Monitor enterprise infrastructure and analyze system performance to proactively identify risks, capacity needs, and opportunities for improvement.
Troubleshoot and resolve complex infrastructure, operating system, hardware, software, and application issues while serving as a technical escalation point.
Configure and support enterprise operating environments, software installations, system updates, and infrastructure components following established standards.
Design, execute, and document infrastructure testing and validation to ensure solutions meet technical and business requirements.
Implement and maintain infrastructure security controls while supporting compliance with organizational standards and best practices.
Coordinate with vendors and third-party providers to resolve technical issues and support infrastructure maintenance activities.
Provide technical guidance, training, and knowledge sharing to users and team members.
Participate in on-call support and respond to critical infrastructure incidents as required.
Evaluate emerging technologies and recommend solutions that improve infrastructure capabilities, operational efficiency, and service delivery.
SKILLS/EDUCATION/EXPERIENCE
REQUIRED
Bachelor's degree in Information Technology, Computer Science, or a related field.
Strong experience managing and troubleshooting infrastructure on IBM i platform.
Ability to diagnose and resolve technical problems using prescribed solution options.
Experience reviewing requirements, evaluating recommendations, and developing appropriate technical plans.
Ability to design, execute, and document systems/service tests.
Conducts gap analyses and contributes to change strategies and implementation planning.
Understands business context and documents current and future states of technical and process architectures.
Analyzes trends and compiles data to support decision-making.
DESIRED
Experience supporting large-scale enterprise infrastructure environments.
Professional certifications related to IBM i, cloud platforms, systems administration, cybersecurity, or infrastructure technologies.
Experience mentoring junior engineers or providing technical leadership.
O'Reilly Auto Parts has a proven track record of growth and stability. O'Reilly is full of successful career stories and believes in a strong promote-from-within philosophy, encouraging you to grow your career along with the organization.
Total Compensation Package:
  • Competitive Wages & Paid Time Off
  • Stock Purchase Plan & 401k with Employer Contributions Starting Day One
  • Medical, Dental, & Vision Insurance with Optional Flexible Spending Account (FSA)
  • Team Member Health/Wellbeing Programs
  • Tuition Educational Assistance Programs
  • Opportunities for Career Growth

O'Reilly Auto Parts is an equal opportunity employer. The Company does not discriminate on the basis of race, religion, color, national origin or ancestry (including immigration status or citizenship), sex, sexual orientation, gender identity, pregnancy (including childbirth, lactation, and related medical conditions,) age (40 and over), veteran status, uniformed service member status, physical or mental disability, genetic information (including testing or characteristics) or another protected status as defined by local, state, or federal law, as applicable.
Qualified individuals with a disability may be entitled to reasonable accommodation under the Americans with Disabilities Act. If you require a reasonable accommodation during the application or employment process, please send an email to: rar@oreillyauto.com or call (800) 471-7431 option , and provide your requested accommodation, and position details.

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