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Senior Bioinformatics Software Engineer Jobs in Prosper, TX

Bioinformatics Pipeline Test Engineer Domain EXP : (Healthcare Domain) Experience: 2+ Years of exp ... Aid in translation of user and software requirements into executable software verification and ...

Senior, Software Engineer

Dallas, TX ยท On-site

$118K - $156K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Frisco, TX ยท On-site

$114K - $151K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Plano, TX ยท On-site

$117K - $155K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Richardson, TX ยท On-site

$111K - $146K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Lewisville, TX ยท On-site

$114K - $150K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Garland, TX ยท On-site

$118K - $156K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Carrollton, TX ยท On-site

$118K - $155K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Irving, TX ยท On-site

$117K - $155K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior, Software Engineer

Allen, TX ยท On-site

$113K - $150K/yr

Senior Software Engineer will be contributing extensively to our embedded Application development, algorithm implementation for complex features to make it more user intuitive and underlying ...

Senior Software Engineer

Mckinney, TX ยท On-site

$113K - $149K/yr

The Senior Software Engineer, Operational Technology is responsible for designing, developing, integrating, and supporting software solutions that enable manufacturing operations, digital ...

Senior Software Engineer

Mckinney, TX ยท On-site

$125 - $150/hr

The Senior Software Engineer, Operational Technologyis responsible fordesigning, developing, integrating, and supporting software solutions that enable manufacturing operations, digital ...

Senior Software Engineer

Mckinney, TX ยท On-site

$113K - $149K/yr

The Senior Software Engineer, Operational Technology is responsible for designing, developing, integrating, and supporting software solutions that enable manufacturing operations, digital ...

Senior Software Engineer

Mckinney, TX ยท On-site

$113K - $149K/yr

The Senior Software Engineer, Operational Technologyis responsible fordesigning, developing, integrating, and supporting software solutions that enable manufacturing operations, digital ...

Senior Software Engineer (.Net) | About the Role As a Senior Software Engineer (.net), you will be responsible for designing, developing, and supporting enterprise applications that drive business ...

Sr. Software Engineer

Dallas, TX ยท Remote

$170K - $220K/yr

Senior Software Engineer - Cloud Infrastructure / Network Automation Industry: Cloud Infrastructure, High-Performance Computing (HPC), Software Engineering Location (City, State): Hybrid (3 days ...

Sr. Software Engineer

Dallas, TX ยท On-site

$170K - $220K/yr

Senior Software Engineer - Cloud Infrastructure / Network Automation Industry: Cloud Infrastructure, High-Performance Computing (HPC), Software Engineering Location (City, State): Hybrid (3 days ...

Senior Software Engineer (.Net) | About the Role As a Senior Software Engineer (.net), you will be responsible for designing, developing, and supporting enterprise applications that drive business ...

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Showing results 1-20

Senior Bioinformatics Software Engineer information

See Prosper, TX salary details

$77.4K

$93.7K

$109.4K

How much do senior bioinformatics software engineer jobs pay per year?

As of Sep 7, 2026, the average yearly pay for senior bioinformatics software engineer in Prosper, TX is $93,659.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,500.00 and $100,700.00 per year, depending on experience, location, and employer.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Prosper, TX?

The most popular types of Bioinformatics Software Engineer jobs in Prosper, TX are:

What cities near Prosper, TX are hiring for Senior Bioinformatics Software Engineer jobs?

Cities near Prosper, TX with the most Senior Bioinformatics Software Engineer job openings:

Infographic showing various Senior Bioinformatics Software Engineer job openings in Prosper, TX as of August 2026, with employment types broken down into 88% Full Time, 8% Part Time, and 4% Contract. Highlights an 88% Physical, 3% Hybrid, and 9% Remote job distribution, with an average salary of $93,659 per year, or $45 per hour.

Bioinformatics Pipeline Test Engineer

Vytwo

Prosper, TX โ€ข On-site

Full-time

Re-posted 10 days ago


Key responsibilities

  • Help with verification and validation protocols and generate test reports for software solutions used in medical devices and LDT products.

  • Assist in translating user and software requirements into executable verification and validation protocols, focusing on various aspects of the software lifecycle.

  • Support the creation of design controls and software documentation, participate in risk assessments, and ensure compliance with regulatory requirements.


Job description

Position Title: Bioinformatics Pipeline Test Engineer
 Domain EXP: (Healthcare Domain)
Experience: 2+ Years of exp
 Location: San Diego CA “Onsite client office”
Duration: 6 Months
JD in brief:
For these candidates, it’s imperative to have NGS pipeline experience or education. Working with Illumina sequencing data, AWS healthomics, Nextflo Type experience working on secondary analysis pipelines
 
Essential Duties:
  • VERIFICATION AND VALIDATION
    •  With direction and guidance from the team lead, help with verification and validation protocols and generate test reports for multiple software solutions used in medical devices and LDT products. 
    • Aid in translation of user and software requirements into executable software verification and validation protocols focusing on various aspects of the software lifecycle.
    • Collaborate with bioinformatics scientists and operations to identify test inputs and understand the development of algorithmic test strategy, testing tools, and testing methodology.
    • Test product functionality and/or confirm product capabilities. 
  • DESIGN CONTROLS 
    1. With direction and guidance from the team lead, help with design controls and appropriate software documentation (e.g. software requirements and/or specifications, architecture documents, software design details doc) for medical device software lifecycle. 
    2. Learn and apply best practices for LDT software and create and manage all applicable documentation. 
    3. Participate in risk assessments for software products, including identification of potential risk mitigations and traceability to software requirements. 
    4. Help with the creation of software documentation, compatible with regulatory requirements. 
  • Utilizing standardized procedures and practices, work on assignments individually and with project team members to achieve department and project objectives and meet deadlines.
  • Exercise excellent verbal and written communication skills with the ability to communicate basic technical information.
  • Work towards challenging goals in a fast-moving environment.
  • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
  • Support and comply with the company’s Quality Management System policies and procedures.
  • Maintain regular and reliable attendance.
  • Ability to act with an inclusion mindset and model these behaviors for the organization.
  • Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day.
  • Ability and means to travel 10% between local Exact Sciences locations. 
  • Ability to travel 5% of working time away from work location, may include overnight/weekend/international travel. 
 Minimum Qualifications
  • B.S. Degree in Computational Biology, Computer Science, or field as outlined in the essential duties. 
  • Familiarity with the development of bioinformatics pipelines within Next Generation Sequencing and PCR applications.
  • Familiarity with production software development lifecycle.
  • Familiarity with best practices for software development (such as Git, agile, code reviews, CI/CD). 
  • Ability to effectively communicate software system designs. 
  • Excellent communication skills (both written and oral) with the ability to communicate complicated ideas and information effectively at all levels. 
  • Demonstrated ability to perform the essential duties of the position with or without accommodation.
 Preferred Qualifications
  • Experience with programming languages, ideally Python. 
  • Familiar with automated software testing, preferably in the context of medical devices software such as bioinformatics analysis pipelines. 
  • Familiarity with container orchestration concepts and systems, e.g. Docker, Kubernetes, etc. 
  • Familiar working with cloud platforms (AWS, GCP, Azure).
  • Familiarity within an FDA-Regulated, Medical Device, Pharmaceutical, Biotech, or other regulated industry, developing CFR 21 Part 11 and IEC 62304 compliant software. 
  • Familiarity with medical device requirements such as Quality System Regulation (21 CFR part 820) ISO 14971 Medical Device Risk Management, ISO 13485, etc. Work experience is strongly preferred. 
  • Familiarity with bioinformatics analysis pipeline frameworks. 
  • Familiarity with software related Cybersecurity risk management such as FDA Cybersecurity guidance, IEC27000 series, IEC 15408, etc. as well as software audits is a plus.
Familiar with managing requirements in a validated RM tool such as JAMA, DOORS, etc.