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Senior Bioinformatics Software Engineer Jobs in Indiana

Senior Software Engineer

Indianapolis, IN · On-site

$117K - $154K/yr

Responsibilities The Senior Software Engineer will join our multi-discipline Agile/DevSecOps Development team in Indianapolis, IN, supporting our NSI program. Provides creative software solutions to ...

Senior Software Engineer

Indianapolis, IN · On-site

$117K - $154K/yr

Responsibilities The Senior Software Engineer will join our multi-discipline Agile/DevSecOps Development team in Indianapolis, IN, supporting our NSI program. Provides creative software solutions to ...

Software Engineer, Senior

Carmel, IN · On-site

$122K - $161K/yr

Information Technology POSITION PURPOSE The Senior Software Engineer provides hands-on technical guidance and support to development teams, ensuring high-quality solutions, best practices, and timely ...

Software Engineer, Senior

Carmel, IN

$122K - $161K/yr

Information Technology POSITION PURPOSE The Senior Software Engineer provides handson technical guidance and support to development teams, ensuring highquality solutions, best practices, and timely ...

Sr. Software Engineer

Fort Wayne, IN · Hybrid

$120K - $159K/yr

We're looking for a passionate and experienced Senior Software Engineer to join our growing team in Fort Wayne . If you're seeking a permanent position that offers challenging projects, a ...

Sr. Software Engineer

Fort Wayne, IN · On-site

$112K - $147K/yr

We're looking for a passionate and experienced Senior Software Engineer to join our growing team in Fort Wayne . If you're seeking a permanent position that offers challenging projects, a ...

Senior Software Engineer

Indianapolis, IN · On-site

$117K - $154K/yr

Responsibilities The Senior Software Engineer will be responsible for integrating with third-party APIs, developing web services, coding in the UI and backend (including SQL) and making architecture ...

Senior Software Engineer

Indianapolis, IN · On-site

$117K - $154K/yr

Responsibilities The Senior Software Engineer will be responsible for integrating with third-party APIs, developing web services, coding in the UI and backend (including SQL) and making architecture ...

Senior Software Engineer

Fort Wayne, IN · On-site

$120K - $140K/yr

Sharetec is looking for a Senior Software Engineer to join our team! At Sharetec, we believe in a people-first business. Our mission is to make millions of people's lives easier by developing ...

Sr Software Engineer

Noblesville, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Sr Software Engineer

Arcadia, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Sr Software Engineer

Indianapolis, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Sr Software Engineer

Zionsville, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Sr Software Engineer

Cicero, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Sr Software Engineer

Brownsburg, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Sr Software Engineer

Fishers, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Sr Software Engineer

Sheridan, IN · On-site

$101K - $169K/yr

We are looking for a Senior Software Engineer who applies the principles of secure software engineering to the design, development, maintenance, testing, and evaluation of software and cloud ...

Showing results 21-40

Senior Bioinformatics Software Engineer information

See Indiana salary details

$80.4K

$97.3K

$113.7K

How much do senior bioinformatics software engineer jobs pay per year?

As of Sep 14, 2026, the average yearly pay for senior bioinformatics software engineer in Indiana is $97,317.00, according to ZipRecruiter salary data. Most workers in this role earn between $89,900.00 and $104,700.00 per year, depending on experience, location, and employer.

What does a senior bioinformatics software engineer do?

A Senior Bioinformatics Software Engineer designs, develops, and maintains software tools and pipelines to analyze biological data, such as genomic or proteomic information. They work closely with scientists and researchers to understand data requirements and translate them into efficient, scalable computational solutions. Their responsibilities often include coding, troubleshooting, optimizing algorithms, as well as mentoring junior engineers and contributing to project planning. Senior engineers are expected to have strong programming skills, a solid understanding of bioinformatics concepts, and experience working with large biological datasets.

What are the key skills and qualifications needed to thrive as a senior bioinformatics software engineer?

To thrive as a Senior Bioinformatics Software Engineer, you need a strong background in computer science, biology, and data analysis, often supported by an advanced degree in bioinformatics or a related field. Expertise with programming languages (such as Python, R, or Java), cloud computing, bioinformatics tools, and version control systems is typically required, along with experience using databases and relevant software frameworks. Strong problem-solving skills, collaboration, and effective communication are crucial soft skills for working with multidisciplinary teams and presenting complex data. These combined skills enable the effective development and maintenance of robust software tools that support cutting-edge biological research and data-driven discoveries.

How does a senior bioinformatics software engineer typically collaborate with cross-functional teams in a research or clinical setting?

Senior Bioinformatics Software Engineers frequently work alongside biologists, data scientists, and clinicians to develop and maintain computational pipelines for data analysis. They play a key role in translating complex biological questions into scalable software solutions, often leading code reviews, mentoring junior developers, and ensuring data integrity. Regular meetings and clear communication are vital, as the role requires aligning technical development with scientific goals and regulatory requirements. This collaborative environment offers opportunities to influence project direction and contribute to impactful discoveries.

What is the difference between Senior Bioinformatics Software Engineer vs Bioinformatics Software Engineer?

AspectSenior Bioinformatics Software EngineerBioinformatics Software Engineer
Required CredentialsBachelor's or Master's in Bioinformatics, Computer Science, or related field; experience in software development and bioinformatics toolsBachelor's or Master's in Bioinformatics, Computer Science, or related field; less emphasis on extensive experience
Work EnvironmentResearch labs, biotech companies, healthcare institutions, often leading projectsResearch teams, biotech firms, academic settings, supporting bioinformatics analysis
Employer & Industry UsageUsed in biotech, pharma, healthcare, research institutionsCommon in similar industries, often as entry to mid-level roles

The main difference between a Senior Bioinformatics Software Engineer and a Bioinformatics Software Engineer lies in experience and responsibility. Senior roles typically require more advanced skills, leadership, and project management, while entry-level roles focus on supporting bioinformatics analysis and software development. Both roles are vital in biotech and research industries, but senior positions involve greater oversight and strategic input.

What are the most commonly searched types of Bioinformatics Software Engineer jobs in Indiana?

The most popular types of Bioinformatics Software Engineer jobs in Indiana are:

What cities in Indiana are hiring for Senior Bioinformatics Software Engineer jobs?

Cities in Indiana with the most Senior Bioinformatics Software Engineer job openings:

Senior Software Engineer

Indianapolis, IN • On-site

$117K - $154K/yr

Full-time

Medical, Retirement, PTO

Re-posted 26 days ago


Job description

CTEC is a leading technology firm that provides modernization, digital transformation, and application development services to the U.S. Federal Government. Headquartered in McLean, VA, CTEC has over 300 team members working on mission-critical systems and projects for agencies such as the Department of Homeland Security, Internal Revenue Service, and the Office of Personnel Management. The work we do effects millions of U.S. citizens daily as they interact with the systems we build. Our best-in-class commercial solutions, modified for our customers’ bespoke mission requirements, are enabling this future every day.

The Company has experienced rapid growth over the past 3 years and recently received a strategic investment from Main Street Capital Corporation (NYSE: MAIN). In addition to our recent growth in Federal Civilian agencies, we are seeking to expand our capabilities in cloud development and footprint in national-security focused agencies within the Department of Defense and U.S. Intelligence Community.

We are currently seeking a  Software Engineer (Senior) to join our team.

Position Summary

The Software Engineer (Senior) is responsible for conducting and/or participating in multidisciplinary research and collaborating with equipment designers and hardware engineers in the planning, design, development, testing, implementation, and utilization of electronic data processing systems software. This role involves analyzing user requirements, advising hardware designers on software-related machine characteristics, and developing system software solutions to support enterprise operations. This position supports the Defense Finance and Accounting Service (DFAS) with their IBM  mainframe-based civilian payroll system.

The ideal candidate will possess extensive experience in software engineering, mainframe technologies, database systems, and performance optimization within complex enterprise environments.

Key Responsibilities

  • Design, develop, test, implement, and maintain software systems and applications.
  • Collaborate with multidisciplinary teams, including hardware engineers and system architects, to develop integrated software solutions.
  • Analyze and determine computer user needs and system requirements.
  • Advise hardware designers on machine characteristics that affect software systems, including:
    • Storage capacity
    • Processing speed
    • Input/output requirements
  • Design and develop compilers, assemblers, utility programs, and operating systems software.
  • Perform software troubleshooting, debugging, and performance tuning.
  • Support system integration, modernization, and enhancement initiatives.
  • Develop and maintain technical documentation and system specifications.
  • Ensure software solutions meet operational, security, and performance standards.
  • Analyze and resolve Action Requests and ABENDs (unplanned program terminations.
  • Design, develop, and maintain micro-applications using Visual Basic for Applications (VBA) within Microsoft Office products (Access, Excel) in response to customer requirements.

Required Qualifications

Candidates submitted for this labor category must possess one of the following required skillsets (not both):

Option 1

  • Expert knowledge and 5–8 years of hands-on experience with:
    • Oracle
    • COGNOS
    • JavaScript

OR

Option 2

  • Expert knowledge and 5–8 years of hands-on experience with:
    • Broadcom Endevor

Preferred Qualifications

  • Expert knowledge and 5–8 years of experience with:
    • IDMS database
    • System performance and measurement
    • COBOL programming
    • JCL
    • Assembler programming (IBM mainframe)
    • REXX scripting; MQ Series (MQSeries 6.0)
    • z/OS mainframe environment; IBM tools: TSO, ISPF, SDSF
    • VBA / Micro-application development (MS Access, MS Excel)

Desired Skills

  • Strong analytical and problem-solving abilities.
  • Experience supporting large-scale enterprise or government environments.
  • Excellent written and verbal communication skills.
  • Ability to work independently and collaboratively within technical teams.
  • Experience with legacy system modernization and integration efforts is a plus.
  • Experience with DFAS, DoD, or civilian payroll systems (e.g., DCPS or equivalent government financial systems).
  • Familiarity with DoD/DFAS security requirements and CAC-enabled environments; understanding of CMMI Level 4 processes.

Education & Experience

  • Bachelor’s degree in Computer Science, Information Systems, Engineering, or related field preferred.

Clearance: Active Secret clearance required.

If you are looking for a fun and challenging environment with talented, motivated people to work with, CTEC is the right place for you. In addition to employee salary, we offer an array of employee benefits including:

  • Paid vacation & Sick leave

  • Health insurance coverage

  • Career training

  • Performance bonus programs

  • 401K contribution & Employer Match

  • 11 Federal Holidays