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Scientist Process Chemistry Jobs (NOW HIRING)

Archer Daniels Midland

$95K - $121K/yr

Senior Research Scientist, Process Chemistry - Decatur, IL This is an exempt level position. Position Summary: The Process Chemistry Group within the ADM Research and Development organization has an ...

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Scientist Process Chemistry information

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$33.5K

$119.3K

$165.5K

How much do scientist process chemistry jobs pay per year?

As of Aug 21, 2026, the average yearly pay for scientist process chemistry in the United States is $119,295.00, according to ZipRecruiter salary data. Most workers in this role earn between $100,000.00 and $144,500.00 per year, depending on experience, location, and employer.

What does a scientist process chemistry do?

A Scientist in Process Chemistry is responsible for developing and optimizing chemical processes used to manufacture pharmaceutical drugs and other chemical products. They design scalable synthesis methods, improve reaction efficiency, and ensure processes are safe, cost-effective, and environmentally friendly. Their work often bridges the gap between laboratory research and large-scale production, collaborating closely with other scientists and engineers to bring new compounds to market.

What are the key skills and qualifications needed to thrive as a scientist process chemistry?

To thrive as a Scientist in Process Chemistry, you need a strong background in organic or analytical chemistry, problem-solving abilities, and typically a PhD or MSc in chemistry or a related field. Familiarity with laboratory instrumentation, process optimization tools, and safety regulations, as well as experience with techniques like chromatography and spectroscopy, is highly valued. Exceptional attention to detail, teamwork, and effective communication are crucial soft skills in this role. These competencies ensure the safe, efficient, and innovative development of scalable chemical processes in pharmaceutical or industrial settings.

How does a scientist process chemistry typically collaborate with cross-functional teams during drug development projects?

As a Scientist in Process Chemistry, you will regularly collaborate with analytical chemists, engineers, and formulation scientists to develop and optimize scalable chemical processes for drug candidates. This collaboration often involves participating in multidisciplinary meetings, sharing data, and integrating feedback to enhance both the efficiency and safety of manufacturing processes. Effective communication and teamwork are essential, as your input directly impacts project timelines, quality, and regulatory compliance.

What is the difference between Scientist Process Chemistry vs Chemist Process Development?

AspectScientist Process ChemistryChemist Process Development
Required CredentialsBachelor's or Master's in Chemistry or Chemical EngineeringBachelor's or Master's in Chemistry or Chemical Engineering
Work EnvironmentLaboratories, manufacturing plants, pilot plantsResearch labs, pilot plants, manufacturing facilities
Industry UsageDevelops and optimizes chemical processes for productionDesigns and scales up processes for commercial manufacturing
Common Search/ComparisonOften compared with Chemist Process Development for career paths and roles

Scientist Process Chemistry focuses on developing and optimizing chemical processes, ensuring efficient production. Chemist Process Development emphasizes designing and scaling processes from lab to manufacturing. Both roles require similar educational backgrounds and work environments but differ in their primary focus within the chemical process lifecycle.

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The most popular types of Scientist Process Chemistry jobs are:

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Scientist Process Chemistry jobs near you
Infographic showing various Scientist Process Chemistry job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 79% Full Time, 16% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $119,295 per year, or $57.4 per hour.

Principal Scientist, Process Chemistry

Calico

South San Francisco, CA • On-site

$197K - $245K/yr

Full-time

Re-posted 6 days ago

Job description

Who We are:

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico's highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.

Position Description: 

Calico is seeking an experienced Process Chemist to join our laboratory-based chemical development team. The ideal candidate brings extensive hands-on experience in process research, route scouting, and scale-up of organic molecules. In this role, you will design, optimize, and execute synthetic processes that enable efficient, safe, and scalable manufacturing of small-molecule intermediates and APIs. This is a lab-focused position requiring strong experimental skills, deep organic chemistry knowledge, and the ability to translate laboratory findings into robust processes. 

Key Responsibilities: 

  • Develop, optimize, and troubleshoot synthetic routes for intermediates and drug substance candidates
  • Perform laboratory experiments to improve yields, selectivity, throughput, and impurity control
  • Conduct detailed reaction analysis using, HPLC, GC, LC-MS, and other analytical techniques
  • Perform impurity identification and synthesis
  • Identify and mitigate process risks related to safety, scalability, and robustness
  • Collaborate with cross-functional partners including analytical chemistry, formulations, and quality assurance 
  • Prepare clear, data-driven reports and present experimental results to project teams
  • Support technology transfer to contract manufacturing organizations, including review of master batch records and process descriptions
  • Maintain accurate lab documentation and adhere to all safety and compliance standards

Position Requirements: 

  • PhD in Organic Chemistry or related field with 8+ years of relevant industrial experience in process chemistry
  • Strong expertise in synthetic organic chemistry and reaction mechanism fundamentals
  • Demonstrated success in developing scalable synthetic processes
  • Proficiency with standard analytical instruments and data interpretation
  • Excellent problem-solving, organization, and communication skills
  • Ability to work independently while contributing effectively to a team environment
  • Familiarity with cGMP and ICH guidelines 
  • Strong attention to detail and a commitment to high-quality experimentation
  • Ability to manage multiple projects and shifting priorities
  • A proactive, collaborative mindset with enthusiasm for process improvement
  • Must be willing to work onsite 5 days a week

The estimated base salary range for this role is $197,000 - $245,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.


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