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Scientist Akta Protein Purification Jobs (NOW HIRING)

Zealand Pharma

$75 - $125/hr

JR360Does it excite you to build a strong foundation in modern protein purification and analytical technologies, and are you eager to grow your scientific career from the ground up? If this sounds ...

Cape Fox SS

Scientist - NIH VRC

Bethesda, MD · On-site

$53.33/hr

Determine scientific rigor in assessing own data and that of others, by providing detailed ... protein purification by AEX, CEX, affinity, SEC, HIC. Column packing and testing. AKTA ...

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How much do scientist akta protein purification jobs pay per hour?

As of Sep 4, 2026, the average hourly pay for scientist akta protein purification in the United States is $33.06, according to ZipRecruiter salary data. Most workers in this role earn between $21.63 and $40.87 per hour, depending on experience, location, and employer.

What does a scientist Akta protein purification do?

A Scientist specializing in Akta protein purification operates and optimizes Akta chromatography systems to isolate and purify proteins from biological samples. They design and execute purification protocols, monitor process parameters, and analyze purified proteins for quality and yield. This role often involves troubleshooting purification issues, maintaining equipment, and documenting results to ensure reproducibility and compliance with laboratory standards. Akta systems are widely used in biotechnology and pharmaceutical labs for producing proteins needed for research, diagnostics, or therapeutics.

What are the key skills and qualifications needed to thrive as a scientist specializing in Akta protein purification?

A Scientist specializing in Akta Protein Purification needs a solid background in biochemistry or molecular biology, typically with a relevant degree and hands-on experience in protein expression and purification. Familiarity with Akta chromatography systems, relevant software (like Unicorn), and analytical techniques such as SDS-PAGE and HPLC is highly valued. Strong problem-solving skills, attention to detail, and the ability to communicate findings effectively are crucial soft skills in this role. These competencies ensure precise, reproducible purification processes and effective collaboration within research teams, driving successful experimental outcomes.

What are some typical challenges faced by a scientist working with ÄKTA protein purification systems?

A Scientist specializing in ÄKTA protein purification often encounters challenges such as optimizing purification protocols for different proteins, troubleshooting system errors, and maintaining reproducibility across batches. Handling complex samples and preventing column clogging or contamination requires careful attention to detail and solid understanding of chromatography principles. Collaboration with research teams, timely documentation, and keeping up with new protocols are also key aspects of the role, which can be demanding but offer valuable opportunities for skill development and scientific impact.

What is the difference between Scientist Akta Protein Purification vs Scientist Protein Biochemist?

AspectScientist Akta Protein PurificationScientist Protein Biochemist
CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fieldsBachelor's or Master's in Biochemistry, Molecular Biology, or related fields
Work EnvironmentLaboratories focusing on protein purification, using chromatography systems like AktaResearch labs performing protein analysis, characterization, and functional studies
Industry UsageBiotech, pharmaceutical, research institutions

Both roles often require similar educational backgrounds and work in laboratory settings. The Scientist Akta Protein Purification specializes in using chromatography systems like Akta for protein isolation, while the Scientist Protein Biochemist may focus more broadly on protein analysis and functional studies. The roles are complementary within biotech and research industries, with overlapping skills but different primary focuses.

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Scientist Akta Protein Purification jobs near you
Infographic showing various Scientist Akta Protein Purification job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 91% Full Time, 4% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $68,765 per year, or $33.1 per hour.

Principal Scientist, Commercial and Late-Stage Purification Process Development

Denali Therapeutics

South San Francisco, CA

$159K - $207K/yr

Full-time

Medical, Retirement

Re-posted 15 hours ago

Key responsibilities

  • Serve as downstream purification technical lead for commercial manufacturing, including process verification, investigations, deviation support, and cross-site alignment.

  • Support lifecycle management activities for commercial products, such as process improvements, tech transfer validation, change management, and regulatory filing updates.

  • Design, oversee, and interpret small-scale process development studies to inform large-scale manufacturing decisions and support root-cause investigations.

Job description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

This position is responsible for driving downstream technical activities for commercial and late-stage process development for Denali's commercial and near-commercial biologics portfolio.

Key Accountabilities/Core Job Responsibilities:

  • Serve as downstream purification technical lead for commercial manufacturing including continued process verification, investigations, deviation support, and cross-site alignment.

  • Support lifecycle management activities for commercial products, including process improvements, tech transfer validation activities, local and cross-site change management, regulatory filing updates (CBE, PAS, Ex-US expansion), and responses to health authority questions.

  • Drive technical continuity and alignment across CDMO and internal manufacturing sites by ensuring process understanding, lessons learned and technical decisions are consistently captured and applied.

  • Design, oversee, and interpret small-scale process development studies that inform large-scale manufacturing decisions, support root-cause investigations, and enable lifecycle improvements.

  • Build and maintain technical risk assessments (e.g., FMEA) and process history files to support robust commercial manufacturing and future late-stage programs.

  • Support the incoming late-stage process development pipeline and commercial programs by applying best practices, platform knowledge, and prior manufacturing experience while contributing to standardization of lifecycle management practices.

Qualifications/Skills:

  • Typically requires a PhD in Biology, Biochemistry, Chemical Engineering, or a related scientific discipline, plus 10+ years of related work experience.

  • Strong experience with commercial process support and technology transfers, downstream purification process characterization, and process validation.

  • Experience managing post-approval changes as a technical SME in collaboration with site, regulatory, supply chain and quality.

  • Experience reviewing batch records, supporting deviation investigations, and assessing process performance during manufacturing campaigns.

  • Proven track record of representing bioprocess functions in cross-functional teams and working effectively with CDMOs.

  • Broad experience in process characterization, design of experiments, and analytics.

  • Experience developing downstream purification processes to support early- or late-stage clinical production.

  • Expertise in AKTA protein purification systems, antibody characterization methods, and other biophysical techniques.

  • Excellent critical thinking, scientific problem-solving, and communication skills

  • Familiarity with BLA authoring and post-approval regulatory support is preferred.

Salary Range: $159,000.00 to $207,000.00 .Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers

This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

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