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Scientist Akta Protein Purification Jobs (NOW HIRING)

Amgen

Scientist - Protein Biochemist

Thousand Oaks, CA · On-site

... Cytiva AKTA, Agilent HPLC) and related software. * Expertise in protein purification methods ... both scientific and cross-functional teams. * Ability to work independently, manage multiple ...

AA2IT

Protein Engineer I , II

Elkton, VA · On-site

$34/hr

... AKTA/Unicorn systems Education Minimum Requirement A bachelor's degree in a relevant scientific ... Recombinant protein production and purification * Protein biochemistry/biochemical skills

AA2IT

Protein Engineer I , II

Elkton, VA · On-site

$34/hr

... AKTA/Unicorn systems Education Minimum Requirement A bachelor's degree in a relevant scientific ... Recombinant protein production and purification * Protein biochemistry/biochemical skills

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How much do scientist akta protein purification jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for scientist akta protein purification in the United States is $33.06, according to ZipRecruiter salary data. Most workers in this role earn between $21.63 and $40.87 per hour, depending on experience, location, and employer.

What does a scientist Akta protein purification do?

A Scientist specializing in Akta protein purification operates and optimizes Akta chromatography systems to isolate and purify proteins from biological samples. They design and execute purification protocols, monitor process parameters, and analyze purified proteins for quality and yield. This role often involves troubleshooting purification issues, maintaining equipment, and documenting results to ensure reproducibility and compliance with laboratory standards. Akta systems are widely used in biotechnology and pharmaceutical labs for producing proteins needed for research, diagnostics, or therapeutics.

What are the key skills and qualifications needed to thrive as a scientist specializing in Akta protein purification?

A Scientist specializing in Akta Protein Purification needs a solid background in biochemistry or molecular biology, typically with a relevant degree and hands-on experience in protein expression and purification. Familiarity with Akta chromatography systems, relevant software (like Unicorn), and analytical techniques such as SDS-PAGE and HPLC is highly valued. Strong problem-solving skills, attention to detail, and the ability to communicate findings effectively are crucial soft skills in this role. These competencies ensure precise, reproducible purification processes and effective collaboration within research teams, driving successful experimental outcomes.

What are some typical challenges faced by a scientist working with ÄKTA protein purification systems?

A Scientist specializing in ÄKTA protein purification often encounters challenges such as optimizing purification protocols for different proteins, troubleshooting system errors, and maintaining reproducibility across batches. Handling complex samples and preventing column clogging or contamination requires careful attention to detail and solid understanding of chromatography principles. Collaboration with research teams, timely documentation, and keeping up with new protocols are also key aspects of the role, which can be demanding but offer valuable opportunities for skill development and scientific impact.

What is the difference between Scientist Akta Protein Purification vs Scientist Protein Biochemist?

AspectScientist Akta Protein PurificationScientist Protein Biochemist
CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fieldsBachelor's or Master's in Biochemistry, Molecular Biology, or related fields
Work EnvironmentLaboratories focusing on protein purification, using chromatography systems like AktaResearch labs performing protein analysis, characterization, and functional studies
Industry UsageBiotech, pharmaceutical, research institutions

Both roles often require similar educational backgrounds and work in laboratory settings. The Scientist Akta Protein Purification specializes in using chromatography systems like Akta for protein isolation, while the Scientist Protein Biochemist may focus more broadly on protein analysis and functional studies. The roles are complementary within biotech and research industries, with overlapping skills but different primary focuses.

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Scientist Akta Protein Purification jobs near you
Infographic showing various Scientist Akta Protein Purification job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 91% Full Time, 4% Part Time, and 3% Contract. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $68,765 per year, or $33.1 per hour.

Principal Scientist, Purification Process Development

Denali Therapeutics

South San Francisco, CA • On-site

$159K - $207K/yr

Full-time

Medical, Retirement

Re-posted 11 days ago

Job description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

This position is responsible for leading, characterizing and validating purification processes, as well as authoring IND/BLA sections to support our large molecule pipeline.

Key Accountabilities/ Core Job Responsibilities:

  • Independently lead purification/downstream process characterization, tech transfer, and late-stage activities, anticipating issues and driving execution.
  • Author protocols, coordinate study execution, review analytical results, generate/review reports, and author IND/BLA sections
  • Coordinate internal team to generate late-stage process characterization and/or validation data packages
  • Support selection/coordination of CDMOs as needed to generate high-quality late-stage data packages
  • Transfer purification processes to CMOs and support ongoing manufacturing activities as needed
  • Support other late-stage projects and apply lessons learned to current projects.
  • Design and execute lab-scale chromatography and filtration studies to inform and support large scale process decisions
  • Maintain existing workflows to provide purification support for cell line and cell culture development activities
  • Execute methods for in-process testing using ELISA, HPLC, UV and SDS-Page based analytics

Qualifications/Skills:

  • Typically requires a PhD in Biology, Biochemistry, Chemical Engineering or related scientific discipline, plus 10+ years' of related work experience.
  • Experience with purification process characterization and validation.
  • Experience reviewing batch records and familiarity with Process Performance Qualification (PPQ) campaigns.
  • Proven track record of representing bioprocess functions in cross-functional teams and working effectively with CMOs.
  • Broad experience in process characterization, design of experiments and analytics.
  • Experience developing protein purification processes to support early or late-stage clinical production.
  • Expertise in AKTA protein purification systems and antibody characterization methods including: HPLC, LC/MS, SDSPAGE, DLS and other biophysical techniques.
  • Excellent critical thinking, scientific problem-solving and communication skills
  • Familiarity with BLA authoring is preferred.
  • Knowledge of process virology, including working with contract labs to plan and execute viral clearance studies is preferred.
Salary Range: $159,000.00 to $207,000.00 .Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers

This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

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