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Research Informatics Director Jobs (NOW HIRING)

Research and Testing Laboratory

The USCAN Director of Informatics Sales will lead a team of Informatics Sales Specialists for the ... Understanding of key challenges faced by clinical, research, pharma, and population genomics ...

Research and Testing Laboratory

The USCAN Director of Informatics Sales will lead a team of Informatics Sales Specialists for the ... Understanding of key challenges faced by clinical, research, pharma, and population genomics ...

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$52K

$117.3K

$299K

How much do research informatics director jobs pay per year?

As of Sep 10, 2026, the average yearly pay for research informatics director in the United States is $117,282.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,000.00 and $136,000.00 per year, depending on experience, location, and employer.

What is a research informatics director?

A Research Informatics Director is a leader responsible for overseeing the development, implementation, and management of informatics systems that support scientific research within an organization. They bridge the gap between information technology and research teams to ensure data is collected, stored, and analyzed efficiently and securely. This role often involves managing teams, setting strategy for data governance, and ensuring compliance with regulatory standards. Research Informatics Directors play a crucial part in advancing research by enabling robust data-driven decision-making.

How does a research informatics director typically collaborate with cross-functional teams to support research initiatives?

A Research Informatics Director regularly works with scientists, IT professionals, data analysts, and project managers to ensure that research data systems align with scientific goals and operational needs. They facilitate communication between technical and scientific teams, translate research requirements into informatics solutions, and oversee the integration of new technologies into existing workflows. This role often involves leading meetings, coordinating data governance efforts, and troubleshooting system challenges to enable smooth, secure, and efficient research processes.

What are the key skills and qualifications needed to thrive as a research informatics director, and why are they important?

To thrive as a Research Informatics Director, you need a strong background in data management, informatics, and biomedical research, typically supported by an advanced degree (such as MS or PhD) in informatics, computer science, or a related field. Familiarity with electronic data capture systems, clinical trial management software, and compliance frameworks like HIPAA is essential, along with certifications such as Certified Clinical Research Professional (CCRP) being advantageous. Outstanding leadership, collaboration, and communication skills help guide multidisciplinary teams and build effective partnerships. These competencies are vital for driving innovation, ensuring data integrity, and supporting impactful research outcomes.

What is the difference between Research Informatics Director vs Research Data Manager?

AspectResearch Informatics DirectorResearch Data Manager
CredentialsTypically requires advanced degrees (Master's or PhD) in informatics, computer science, or related fieldsUsually holds a Bachelor's or Master's degree in data management, information science, or related areas
Work EnvironmentLeads teams in research institutions, overseeing informatics strategies and systemsManages research data collection, storage, and quality control within research projects
Employer & IndustryAcademic, healthcare, or biotech research organizationsResearch institutions, universities, or clinical research settings

The Research Informatics Director focuses on strategic leadership of research informatics systems and teams, often with a broader scope and higher-level responsibilities. In contrast, the Research Data Manager handles day-to-day data management tasks, ensuring data quality and compliance within research projects.

What cities are hiring for Research Informatics Director jobs?

Cities with the most Research Informatics Director job openings:

What states have the most Research Informatics Director jobs?

States with the most job openings for Research Informatics Director jobs include:

What are popular job titles related to Research Informatics Director jobs?

For Research Informatics Director jobs, the most frequently searched job titles are:

Infographic showing various Research Informatics Director job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 88% Full Time, 9% Part Time, and 1% Contract. Highlights an 79% Physical, 3% Hybrid, and 18% Remote job distribution, with an average salary of $117,282 per year, or $56.4 per hour.

Associate Director, Clinical Data Systems and Informatics

San Diego, CA • On-site

ClearNote Health
Biotechnology Research and Development • 11 - 50 employees
Learn more about ClearNote Healthexternal

$155K - $190K/yr

Full-time

Re-posted 11 days ago

Job description

Job Title: Associate Director, Clinical Data Systems and Informatics
Location: San Mateo, CA; San Diego, CA
ClearNote Health is an early cancer detection company focused on the development and commercialization of non-invasive epigenomic tests to detect cancer through a standard blood draw, earlier than existing methods and when the disease is still treatable. Leveraging its novel liquid biopsy technology, ClearNote Health is initially focused on high-mortality cancers with the greatest need for early detection, starting with pancreatic and ovarian cancers.
Position Summary:
The Associate Director, Clinical Data Systems and Informatics will contribute to the development of our diagnostic tests through management of clinical data flow into our data warehouse and reporting on that data. This role will be instrumental to the success of our research efforts and our clinical trials with the management and organization clinical data. The data from the systems overseen will be integrated into our discovery and clinical research efforts, enabling precise, rigorous scientific decisions leading to the development of screening tests that meet our team's high standards.
Key Responsibilities:
  • Coordinate with clinical operations personnel to ensure data from Electronic Data Capture (EDC) systems is delivered into our Data Warehouse (DWH)
  • Author and maintain data management plan (DMP) for clinical studies, ensuring alignment with study requirements and ICH E6 (R2) GCP standards
  • Oversee the design, build, and validation of electronic case report forms (eCRFs), including edit check programming and UAT execution.
  • Manage data flow from site to EDC, ensuring timely resolution of queries and database integrity.
  • Develop and maintain data validation plans, including programmatic and manual edit checks to support ALCOA+ data quality principles
  • Lead the creation of data review listings and metrics reports to support ongoing data cleaning and study oversight
  • Coordinate with CRO or external CDM vendors on data management deliverables, timelines, and quality standards
  • Support database lock activities including final data reconciliation, discrepancy resolution, and lock documentation
  • Maintain TMF-relevant CDM documentation in accordance with regulatory inspection readiness standards
  • Coordinate with clinical operations personnel to ensure data from non-EDC sources (e.g. ad hoc spreadsheets) is delivered into our DWH
  • Transform clinical data in the DWH into forms suitable for use by the entire research and development team
  • Own the accuracy and integrity of all clinical data in the DWH
  • Serve as an SME on DWH clinical data for the research and development team
  • Coordinate with our Regulatory/QA team to ensure clinical data flow and the DWH are compliant with procedural and regulatory requirements
  • Define methods and metrics for assessing data quality; monitor and maintain data quality
  • Integrate clinical data with other corporate data
  • Provide project status updates to cross-functional team members.
  • Provide technical guidance and training in the use of clinical data in the DWH
Qualifications:
  • 7+ years of clinical data management experience
  • Hands-on, technically adept
  • Experience working in hybrid CDM role spanning both hands-on study execution and oversight
  • Software engineering expertise
  • Expert understanding of database and DWH concepts
  • Experience with EDC platforms including eCRF design, edit check authorizing, and study administration
  • Ability to author CDM-critical documents including DMPs, CRF completion guidelines, data validation plan, and SOPs
  • Working knowledge of clinical data standards (CDASH/CDISC preferred)
  • Familiarity with query management workflows and data lock/freeze procedures
  • Deep expertise in SQL
  • DBT experience required
  • Python experience preferred
  • Strong writing skills and experience documenting your work
  • In-depth clinical database build knowledge. Medrio experience preferred.
  • Working knowledge of Good Clinical Practices, clinical research, clinical trial process and related regulatory requirements
  • Familiar with cancer related medical classifications and ontologies such as ICD-10
  • Strong communication skills
The anticipated salary range for this position is $155,000 - $190,000. The actual salary will be dependent on various factors that may include experience level, knowledge, skills and abilities.
Come join us in addressing large healthcare needs through precision epigenomic medicine!
ClearNote Health is an exciting life science company that is reinventing non-invasive molecular diagnostic testing using next generation epigenomic technologies. We are passionate and dedicated to discovering and developing medicines that will make a significant difference in cancer and other epigenomic-driven diseases. Our technologies provide novel insight and quantitation of human health and disease, with our focus on precision medicine applications improving both clinical and health system outcomes. Our company was founded based on pioneering work in the Stanford laboratory of Stephen Quake, with advisors from Stanford and UCSF.
We look for extraordinary lifelong learners with a passion and growth mindset for these areas, and for combining biological ingenuity with AI and data analysis. Led by a team with decades of experience bringing products from concept to market, we are an equal opportunity employer and value diversity at our company.
We provide generous benefits to all employees including stock options. We are building a world-class company, based in San Diego and San Mateo.
Our commitment to Diversity, Equity, Inclusion, and Belonging:
We celebrate diversity in perspectives and backgrounds, and this is reflected in our innovation, our mission, and values. Our differences make us unique, help us innovate, and allow us to persevere. We strive to achieve representation and inclusion and redefine the possible in patients living longer lives.

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