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Research Informatics Director Jobs (NOW HIRING)

Quest Oracle Community

$100 - $125/hr

... informatics and research data analytics to ensure success of research projects. Designs and ... Ability to be self-directed and work independently under strict deadlines. * Ability to deal ...

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Aptive

Director Health Informatics

Using their informatics expertise, the Health Informatics Director will influence internal and ... Design and develop advanced operations research and data science techniques, diagnostic and ...

Aptive

Director Health Informatics

Using their informatics expertise, the Health Informatics Director will influence internal and ... Design and develop advanced operations research and data science techniques, diagnostic and ...

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$52K

$117.3K

$299K

How much do research informatics director jobs pay per year?

As of Sep 9, 2026, the average yearly pay for research informatics director in the United States is $117,282.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,000.00 and $136,000.00 per year, depending on experience, location, and employer.

What is a research informatics director?

A Research Informatics Director is a leader responsible for overseeing the development, implementation, and management of informatics systems that support scientific research within an organization. They bridge the gap between information technology and research teams to ensure data is collected, stored, and analyzed efficiently and securely. This role often involves managing teams, setting strategy for data governance, and ensuring compliance with regulatory standards. Research Informatics Directors play a crucial part in advancing research by enabling robust data-driven decision-making.

How does a research informatics director typically collaborate with cross-functional teams to support research initiatives?

A Research Informatics Director regularly works with scientists, IT professionals, data analysts, and project managers to ensure that research data systems align with scientific goals and operational needs. They facilitate communication between technical and scientific teams, translate research requirements into informatics solutions, and oversee the integration of new technologies into existing workflows. This role often involves leading meetings, coordinating data governance efforts, and troubleshooting system challenges to enable smooth, secure, and efficient research processes.

What are the key skills and qualifications needed to thrive as a research informatics director, and why are they important?

To thrive as a Research Informatics Director, you need a strong background in data management, informatics, and biomedical research, typically supported by an advanced degree (such as MS or PhD) in informatics, computer science, or a related field. Familiarity with electronic data capture systems, clinical trial management software, and compliance frameworks like HIPAA is essential, along with certifications such as Certified Clinical Research Professional (CCRP) being advantageous. Outstanding leadership, collaboration, and communication skills help guide multidisciplinary teams and build effective partnerships. These competencies are vital for driving innovation, ensuring data integrity, and supporting impactful research outcomes.

What is the difference between Research Informatics Director vs Research Data Manager?

AspectResearch Informatics DirectorResearch Data Manager
CredentialsTypically requires advanced degrees (Master's or PhD) in informatics, computer science, or related fieldsUsually holds a Bachelor's or Master's degree in data management, information science, or related areas
Work EnvironmentLeads teams in research institutions, overseeing informatics strategies and systemsManages research data collection, storage, and quality control within research projects
Employer & IndustryAcademic, healthcare, or biotech research organizationsResearch institutions, universities, or clinical research settings

The Research Informatics Director focuses on strategic leadership of research informatics systems and teams, often with a broader scope and higher-level responsibilities. In contrast, the Research Data Manager handles day-to-day data management tasks, ensuring data quality and compliance within research projects.

What cities are hiring for Research Informatics Director jobs?

Cities with the most Research Informatics Director job openings:

What states have the most Research Informatics Director jobs?

States with the most job openings for Research Informatics Director jobs include:

What are popular job titles related to Research Informatics Director jobs?

For Research Informatics Director jobs, the most frequently searched job titles are:

Infographic showing various Research Informatics Director job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 88% Full Time, 9% Part Time, and 1% Contract. Highlights an 79% Physical, 3% Hybrid, and 18% Remote job distribution, with an average salary of $117,282 per year, or $56.4 per hour.

Director, Research Informatics

South San Francisco, CA • On-site

Denali Therapeutics
Scientific Research and Development Services • 201 - 500 employees
Learn more about Denali Therapeuticsexternal

$204K - $265K/yr

Full-time

Medical, Retirement

Posted 29 days ago

Job description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

Research Informatics is responsible for the scientific data platforms and internal software that underpin the full research and development pipeline at Denali Therapeutics. This function owns the strategy, implementation, and ongoing support of the digital tools that enable scientists to register molecular entities and to track, analyze, and document associated experimental data across the full lifecycle, from early discovery through translational and development handoffs. These tools include Denali's Electronic Laboratory Notebook (ELN), the internal experiment data management platforms that underpin our scientific documentation, and the AI capabilities that unlock the full value of our data.
The Director of Research Informatics will lead this function, serving as the strategic and operational owner of our scientific data platforms, including Benchling, Dotmatics, and our internal software and AI tool integration. This individual will define the informatics roadmap, drive stakeholder alignment behind it, and build a high-caliber engineering team, while serving as a trusted technical partner to Discovery, enterprise IT, and other operational leadership. This is a hands-on leadership role: the Director will set technical direction and make software architecture and design-space decisions, not simply manage from a distance.

Key Accountabilities / Core Job Responsibilities

  • Owns the strategy, roadmap, and operational delivery of Research Informatics, including Benchling, Dotmatics, internal software systems, and AI integration.

  • Leads and grows a team responsible for platform support, configuration, validation, and continuous improvement across Discovery, Development, and Technical Operations.

  • Partners with scientists and lab operations leads to translate business and scientific requirements into scalable, well-engineered platform solutions.

  • Serves as subject matter expert on ELN capabilities and experiment data workflows, advising on platform selection and integration strategy.

  • Communicates platform strategy, status, and risk clearly to senior stakeholders, from group leaders to senior management.

  • Engages hands-on in configuration and platform build work, alongside strategic oversight.

  • Drives vendor relationships and manages platform migrations, escalations, and contract performance.

  • Explores and integrates next-generation, AI-driven experiment capture concepts, including passive documentation architectures that reduce manual interface dependency while preserving compliant, attributable records.

  • Owns roadmap prioritization and backlog decisions, balancing input from scientific, engineering, and IT stakeholders.

  • Leads direct report(s) through annual goal setting, growth planning, adherence to company policies, maintains training compliance, and provides ongoing feedback on growth, development, and areas of improvement.

Qualifications/Skills

  • Typically requires a Bachelor's degree in a technical field (computer science, data science, engineering, or related); advanced degree preferred.

  • Typically requires 10+ years building and delivering software solutions, including 7+ years in pharma, biotech, or life sciences supporting laboratory informatics or scientific platforms.

  • Typically requires 8+ years of people management experience, including building and growing engineering teams.

  • Hands-on expertise with scientific data platforms (e.g., Benchling, Dotmatics) and experience leading ELN/registry migrations preferred.

  • Experience partnering with enterprise IT on security, licensing, and infrastructure, and familiarity applying AI/ML workflows to biological or chemical data, preferred.

Salary Range: $204,000.00 to $265,000.00 .Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers

This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

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