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Research Associate Protein Purification Jobs in Raleigh, NC

Recent, hands-on experience with protein purification methods. Recent experience with recombinant protein expression and purification from E. coli. Strong organizational skills with attention to ...

PhD in Structural Biochemistry with experience in protein engineering, purification of challenging ... Present research findings at scientific conferences. Choose Duke. Duke is an Equal Opportunity ...

... protein from cells and tissues; and (2) quantitative PCR (qPCR), RT-PCR, ddPCR, ELISA, SDS-PAGE ... Perform plasmid purification, genomic DNA extraction, RNA extraction, and PCR-based assays (PCR ...

... protein from cells and tissues; and (2) quantitative PCR (qPCR), RT-PCR, ddPCR, ELISA, SDS-PAGE ... Perform plasmid purification, genomic DNA extraction, RNA extraction, and PCR-based assays (PCR ...

Senior Research Associate Position in Epitranscriptomics in the Meyer Lab (Duke University) The ... We are particularly interested in uncovering how m6A shapes RNA: protein interactions, influences ...

Senior Research Associate Position in Epitranscriptomics in the Meyer Lab (Duke University) The ... We are particularly interested in uncovering how m6A shapes RNA: protein interactions, influences ...

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Research Associate Protein Purification information

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How much do research associate protein purification jobs pay per hour?

As of Jul 27, 2026, the average hourly pay for research associate protein purification in Raleigh, NC is $31.63, according to ZipRecruiter salary data. Most workers in this role earn between $25.48 and $35.96 per hour, depending on experience, location, and employer.

What are some common challenges faced by Research Associates specializing in protein purification, and how can they be addressed?

Research Associates in protein purification often encounter challenges such as protein instability, low yield, and contamination during the purification process. Addressing these issues typically involves optimizing buffer conditions, adjusting purification protocols, and troubleshooting equipment. Collaboration with experienced colleagues and regular communication with other lab teams, such as molecular biology or analytical groups, also plays a key role in overcoming technical obstacles and ensuring high-quality results. Staying current with new purification technologies and best practices can further help mitigate common problems in this role.

What are the key skills and qualifications needed to thrive as a Research Associate in Protein Purification, and why are they important?

To thrive as a Research Associate in Protein Purification, you need a strong background in biochemistry or related fields, experience with protein expression and purification techniques, and typically a bachelor's or master's degree in the life sciences. Familiarity with chromatography systems (e.g., FPLC, HPLC), SDS-PAGE analysis, and laboratory information management systems (LIMS) is often required. Attention to detail, problem-solving skills, and the ability to work collaboratively are essential soft skills in this role. These skills and qualities ensure accurate experimental results, efficient workflow, and successful advancement of research projects.

What does a Research Associate in Protein Purification do?

A Research Associate in Protein Purification is responsible for isolating and purifying proteins from various biological sources using techniques such as chromatography, filtration, and centrifugation. They often work in laboratories, supporting scientific research and development projects by preparing high-quality protein samples for analysis or further experimentation. Their role may also include optimizing purification protocols, maintaining detailed laboratory records, and troubleshooting technical issues. This position is vital in biotech, pharmaceutical, and academic research settings where protein studies are essential.

What is the difference between Research Associate Protein Purification vs Research Associate Cell Culture?

AspectResearch Associate Protein PurificationResearch Associate Cell Culture
Required SkillsProtein purification techniques, chromatography, protein analysisCell culture, aseptic techniques, media preparation
Work EnvironmentLaboratories focused on biochemistry and protein analysisCell biology labs, tissue culture facilities
Common EmployerBiotech, pharmaceutical, research institutionsBiotech, pharmaceutical, research institutions

Research Associate Protein Purification and Research Associate Cell Culture roles share similar educational backgrounds and work environments but focus on different technical skills. Protein purification involves isolating and analyzing proteins, while cell culture emphasizes growing and maintaining cells. Both roles are essential in biotech and research settings, often overlapping in industry usage.

What job categories do people searching Research Associate Protein Purification jobs in Raleigh, NC look for? The top searched job categories for Research Associate Protein Purification jobs in Raleigh, NC are:
Research Assoc I-III Molecular Bio/Biochem

Research Assoc I-III Molecular Bio/Biochem

Epicypher Inc

Durham, NC โ€ข On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 8 days ago


Job description

Position Summary

The Research Associate I/II/III (Molecular Biology & Biochemistry) is a key contributor to the development, manufacturing, and delivery of EpiCypherโ€™s epigenetic research tools. This role combines hands-on molecular biology and biochemistry expertise with a strong focus on manufacturing execution, process optimization, quality and operational reliability.

The ideal candidate is technically proficient, highly organized, adaptable, and quality-driven, with the ability to successfully operate in a fast-paced and evolving environment. This role supports both process development and routine manufacturing activities in accordance with approved SOPs, quality standards, and company policies.

Key Responsibilities:

Manufacturing & Production Operations

  • Manufacture reagents, products, and kits according to approved SOPs, batch records, and quality standards.
  • Execute molecular biology and biochemistry workflows including PCR, recombinant protein expression and purification, chromatography, SDS-PAGE, Western blotting and related analytical techniques.
  • Support manufacturing scheduling, material readiness, and operational continuity for commercial and internal production needs.

Process Development & Optimization

  • Contribute to process development, process transfer, and scale-up activities for epigenetic reagent and kit manufacturing.
  • Optimize process parameters to improve yield, productivity, consistency, and product quality.
  • Troubleshoot process deviations, technical issues, and workflow bottlenecks in collaboration with senior staff.

Documentation & Compliance

  • Maintain accurate and complete documentation including batch records, process data, deviation reporting, and equipment logs.
  • Operate in compliance with SOPs, internal quality systems, and established documentation practices.
  • Support continuous improvement efforts related to process robustness, traceability, and operational efficiency.

Collaboration & Communication

  • Work cross-functionally with Product Development, R&D, Quality Control, and Operations to support project timelines and manufacturing goals.
  • Communicate technical findings, operational issues, and identified risks effectively to team members and stakeholders.
  • Present data at internal meetings and contribute to technical reports, SOP updates, and process documentation.

Qualifications:

Minimum Requirements

  • BS/MS degree in Molecular Biology, Biochemistry, Biotechnology, Biological Sciences, or a related field.
  • Solid molecular biology and/or protein biochemistry background with the ability to rapidly learn and apply new technical skills.
  • Relevant laboratory or manufacturing experience in biotechnology, molecular biology, protein purification, or bioprocessing environments. Prior industry experience is preferred but not required.
  • Hands-on experience with molecular biology and biochemical techniques such as PCR, protein expression and purification, FPLC/HPLC, SDS-PAGE, and Western blotting strongly preferred.
  • Experience with epigenetic-related technologies, liquid handling automation, or laboratory robotics (e.g., Tecan platforms) is a plus.

Skills & Competencies

  • Strong attention to detail and commitment to quality and data integrity.
  • Excellent organizational and time-management skills in a fast-paced environment.
  • Strong troubleshooting, analytical, and problem-solving abilities.
  • Ability to manage shifting priorities and support multiple workflows simultaneously
  • Effective written and verbal communication skills.
  • Ability to work both independently and collaboratively within cross-functional teams.
  • Experience operating in deadline-driven or production-oriented laboratory environments is highly valued.

Compensation:

  • Competitive salary commensurate with experience.
  • Generous benefits package includes subsidized health, dental, and vision; paid vacation, sick leave, and parental leave; federal and floating holidays; mental health day; 401(k) matching up to 6%; professional development reimbursement; paid life insurance and stock options.

EpiCypherโ€™s mission is to lead the epigenetics field in developing high-quality products and services that accelerate chromatin science to improve and extend human life. In this mission, we hold our core values in high regard: mutual respect, fairness, commitment to excellence, customer success, scientific advancement, effective communication, integrity, and teamwork.

EpiCypher is committed to providing a work environment that is free from all forms of harassment, discrimination, and inequality. We provide equal employment opportunities to all employees and applications for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.