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Research Associate Protein Purification Jobs in Raleigh, NC

Duke University

Research Scholar

Durham, NC

Research Scholar - Director of the Protein Design and Analysis Core The Research Scholar role will ... protein expression systems (bacterial, mammalian, insect), purification, and quality control is ...

Duke University

Research Scholar

Durham, NC · On-site

Research Scholar - Director of the Protein Design and Analysis Core The Research Scholar role will ... protein expression systems (bacterial, mammalian, insect), purification, and quality control is ...

Duke University

Associate in Research

Durham, NC · On-site

Associate in Research Tata Lab, Duke University School of Medicine Perform a variety of complex ... Performs standard molecular biology techniques (cloning, PCR, DNA, RNA, and protein extraction, etc.

Duke University

Associate in Research

Durham, NC · On-site

Associate in Research Tata Lab, Duke University School of Medicine Perform a variety of complex ... Performs standard molecular biology techniques (cloning, PCR, DNA, RNA, and protein extraction, etc.

NCSU

Research Scholar, Metabolomics

Raleigh, NC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

METRIC provides researchers access to the following services: * Mass spectrometry: small molecule ... NMR spectroscopy: small molecule and macromolecular solution structures, protein-ligand ...

Duke University

Postdoctoral Associate

Durham, NC

Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more ... Experience with expression and purification of proteins from mammalian cells, measurement of ...

Duke University

POSTDOCTORAL ASSOCIATE

Durham, NC · On-site

Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more ... Experience with expression and purification of proteins from mammalian cells, measurement of ...

Duke University

Postdoctoral Associate

Durham, NC · On-site

Available research areas include: * Mechanistic studies of how m6A alters RNA:protein interactions across the transcriptome * Defining the roles of m6A and RNA-binding proteins in brain development ...

Duke University

Postdoctoral Associate

Durham, NC

Available research areas include: * Mechanistic studies of how m6A alters RNA:protein interactions across the transcriptome * Defining the roles of m6A and RNA-binding proteins in brain development ...

KBI Biopharma, Inc.

In Process Research Associate

Durham, NC · On-site

$19.23/hr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

We are seeking an In-Process Support Associate with strong protein chemistry background to perform cGMP in-process analytical support. These services include in-process and release testing for drug ...

KBI Biopharma, Inc.

In Process Research Associate

Durham, NC

$19.23/hr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

We are seeking an In-Process Support Associate with strong protein chemistry background to perform cGMP in-process analytical support. These services include in-process and release testing for drug ...

UNC-Chapel Hill

Laboratory Assistant

Chapel Hill, NC · On-site

$19/hr

... research associates, 700 undergraduate majors, and an annual total of approximately 10,000 ... protein GEN1 interactions with different structured DNA substrates. The applicant will be expected ...

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All JobsResearch Associate Protein Purification JobsResearch Associate Protein Purification Jobs in Raleigh, NC

Research Associate Protein Purification information

See Raleigh, NC salary details

$15

$31

$45

How much do research associate protein purification jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for research associate protein purification in Raleigh, NC is $31.63, according to ZipRecruiter salary data. Most workers in this role earn between $25.48 and $35.96 per hour, depending on experience, location, and employer.

What does a research associate in protein purification do?

A Research Associate in Protein Purification is responsible for isolating and purifying proteins from various biological sources using techniques such as chromatography, filtration, and centrifugation. They often work in laboratories, supporting scientific research and development projects by preparing high-quality protein samples for analysis or further experimentation. Their role may also include optimizing purification protocols, maintaining detailed laboratory records, and troubleshooting technical issues. This position is vital in biotech, pharmaceutical, and academic research settings where protein studies are essential.

What are the key skills and qualifications needed to thrive as a research associate in protein purification?

To thrive as a Research Associate in Protein Purification, you need a strong background in biochemistry or related fields, experience with protein expression and purification techniques, and typically a bachelor's or master's degree in the life sciences. Familiarity with chromatography systems (e.g., FPLC, HPLC), SDS-PAGE analysis, and laboratory information management systems (LIMS) is often required. Attention to detail, problem-solving skills, and the ability to work collaboratively are essential soft skills in this role. These skills and qualities ensure accurate experimental results, efficient workflow, and successful advancement of research projects.

What are some common challenges faced by research associates specializing in protein purification, and how can they be addressed?

Research Associates in protein purification often encounter challenges such as protein instability, low yield, and contamination during the purification process. Addressing these issues typically involves optimizing buffer conditions, adjusting purification protocols, and troubleshooting equipment. Collaboration with experienced colleagues and regular communication with other lab teams, such as molecular biology or analytical groups, also plays a key role in overcoming technical obstacles and ensuring high-quality results. Staying current with new purification technologies and best practices can further help mitigate common problems in this role.

What is the difference between Research Associate Protein Purification vs Research Associate Cell Culture?

AspectResearch Associate Protein PurificationResearch Associate Cell Culture
Required SkillsProtein purification techniques, chromatography, protein analysisCell culture, aseptic techniques, media preparation
Work EnvironmentLaboratories focused on biochemistry and protein analysisCell biology labs, tissue culture facilities
Common EmployerBiotech, pharmaceutical, research institutionsBiotech, pharmaceutical, research institutions

Research Associate Protein Purification and Research Associate Cell Culture roles share similar educational backgrounds and work environments but focus on different technical skills. Protein purification involves isolating and analyzing proteins, while cell culture emphasizes growing and maintaining cells. Both roles are essential in biotech and research settings, often overlapping in industry usage.

What are popular job titles related to Research Associate Protein Purification jobs in Raleigh, NC?

For Research Associate Protein Purification jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Research Associate Protein Purification jobs in Raleigh, NC look for?

The top searched job categories for Research Associate Protein Purification jobs in Raleigh, NC are:

Research Associate Protein Purification jobs near you

Research Scholar

Duke University

Durham, NC

Full-time

Re-posted 14 days ago

Duke University rating

6.7

Company rating: 6.7 out of 10

Based on 55 frontline employees who took The Breakroom Quiz

487th of 619 rated colleges and universities

Job description

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

 

Research Scholar - Director of the Protein Design and Analysis Core

The Research Scholar role will serve as the Director of the Protein Design and Analysis Core provides visionary scientific and operational leadership for a multidisciplinary core facility dedicated to the de novo design, engineering, characterization, and structural analysis of proteins. The Director oversees a team of scientists, engineers, and technical staff, and serves as a strategic partner to internal research programs and external collaborators. This role demands expertise at the intersection of computational protein design, structural biology, and biophysical characterization, combined with the management acumen to operate a high-throughput, service-oriented research core.

Qualified candidates will have a Ph.D. in Biochemistry, Structural Biology, Biophysics, Computational Biology, Bioengineering, or a closely related field with a minimum of 8-10 years of post-doctoral research or industry experience, with at least 3-5 years in a leadership or supervisory role.

Be Bold.                                         

Demonstrated deep expertise in protein expression systems (bacterial, mammalian, insect), purification, and quality control is essential as well as a strong command of biophysical characterization techniques (SPR, ITC, SEC-MALS, CD, DLS, HDX-MS). Proficiency in structural biology methods (X-ray crystallography and/or cryo-EM) and associated software pipelines is required, with hands-on experience with computational protein design platforms (Rosetta, AlphaFold, ESMFold, or equivalent) and relevant scripting languages (Python, PyMOL scripting, etc.).

 

Choose Duke.                                                                                                                                                                                                                                                          

Highly qualified candidates will have a proven track record of scientific productivity evidenced by peer-reviewed publications in high-impact journals, with demonstrated ability to manage complex, multi-stakeholder projects and lead interdisciplinary teams.

Duke University is an Equal Opportunity Employer. Please note that Duke will specifically seek information about past misconduct or policy violations (in the past ten (10) years) and/or relevant pending investigations as part of the application process. Disclosures will not be an automatic bar to hiring but, instead, will initiate further dialogue regarding past actions and steps taken to address them. Disclosures will not be shared with search committees during the application review process.


Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.


Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions:

Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


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About Duke University

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Duke is regarded as one of America's leading research universities. Located in Durham, North Carolina, Duke is positioned in the heart of the Research Triangle, which is ranked annually as one of the best places in the country to work and live. Duke has more than 15,000 students who study and conduct research in its 10 undergraduate, graduate, and professional schools. With about 40,000 employees, Duke is the third largest private employer in North Carolina, and it now has international programs in more than 150 countries.

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Colleges, universities, and professional schools and hospitals

Company size

10,000+ Employees

Headquarters location

Durham, NC, US

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