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Research Associate Formulation Development Jobs

Cresilon

$150 - $200/hr

Learn more at www.cresilon.com The R&D Manager/Principal Scientist - Polymer Formulation will lead the design, development, and implementation of novel formulations and polymer materials for use in ...

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Research Associate Formulation Development information

What does a research associate formulation development do?

A Research Associate in Formulation Development is responsible for designing, developing, and optimizing pharmaceutical formulations, such as tablets, capsules, or injectables. They conduct experiments to evaluate the stability, efficacy, and quality of drug products, often working in a laboratory setting. Their work involves collaborating with scientists, documenting results, and ensuring compliance with regulatory standards. This role is crucial for bringing new medications from the concept stage to clinical trials and eventual market approval.

What are the key skills and qualifications needed to thrive as a research associate formulation development?

To thrive as a Research Associate in Formulation Development, you need a background in pharmaceutical sciences, chemistry, or related fields, often supported by a relevant degree and laboratory experience. Familiarity with analytical instruments (such as HPLC, GC, and dissolution testers), formulation software, and Good Laboratory Practice (GLP) or Good Manufacturing Practice (GMP) guidelines is typically required. Strong attention to detail, problem-solving skills, and effective teamwork are essential soft skills in this role. These competencies ensure accurate formulation design, regulatory compliance, and the successful development of safe and effective drug products.

What are some common challenges faced by a research associate formulation development, and how can they be managed?

Research Associates in Formulation Development often encounter challenges such as optimizing formulations to achieve the desired stability, efficacy, and manufacturability. Balancing multiple project timelines and adapting to changes in experimental protocols can also be demanding. Effective communication with cross-functional teams, meticulous documentation, and staying current with new technologies are key strategies for managing these challenges. Additionally, being proactive in troubleshooting and seeking mentorship from experienced colleagues can help navigate complex formulation problems.

What is the difference between Research Associate Formulation Development vs Research Associate Quality Control?

AspectResearch Associate Formulation DevelopmentResearch Associate Quality Control
CredentialsBachelor's/Master's in Pharmacy, Chemistry, or related fieldBachelor's/Master's in Chemistry, Biology, or related field
Work EnvironmentLaboratories focused on formulation and product developmentLaboratories conducting testing and quality analysis
Industry UsagePharmaceutical and biotech companies involved in product formulationManufacturing and quality assurance departments in pharma
Common Search IntentUnderstanding formulation roles and responsibilitiesComparing quality control roles and tasks

Research Associate Formulation Development focuses on creating and optimizing drug formulations, while Research Associate Quality Control emphasizes testing and ensuring product quality. Both roles are essential in pharmaceutical development but differ in their primary functions and work environments.

What cities are hiring for Research Associate Formulation Development jobs?

Cities with the most Research Associate Formulation Development job openings:

What states have the most Research Associate Formulation Development jobs?

States with the most job openings for Research Associate Formulation Development jobs include:

What are popular job titles related to Research Associate Formulation Development jobs?

For Research Associate Formulation Development jobs, the most frequently searched job titles are:

Infographic showing various Research Associate Formulation Development job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 82% Full Time, 14% Part Time, and 2% Contract. Highlights an 87% Physical, 2% Hybrid, and 11% Remote job distribution.

Research Associate II, CRISPR-X - LNP

South Boston, MA • On-site

Crispr Therapeutics
Biotechnology Research and Development • 201 - 500 employees
Learn more about Crispr Therapeuticsexternal

Full-time

Re-posted 19 days ago

Job description

Job Description:
Company Overview
Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY® (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary
We are seeking a highly motivated Research Associate II to support the design, development, and optimization of novel lipid nanoparticle (LNP) formulations to advance our non-viral delivery platform for hepatic and extra-hepatic tissues, and enable next-generation genome editing therapies from discovery through clinical translation.
The ideal candidate will bring hands-on expertise in LNP formulation development, scale-up, analytical characterization, chemistry, and process development, with a strong passion for innovation in nucleic acid delivery technologies. This individual will join the dynamic, fast-growing, and highly collaborative CRISPR-X division and contribute to both platform technology innovation and preclinical therapeutic programs.
In this role, the candidate will work cross-functionally to develop and characterize advanced delivery systems for emerging editing modalities, helping drive transformative gene editing therapies toward patients with unmet medical needs.
Responsibilities
  • Design, optimize, characterize, and execute lipid nanoparticle (LNP) formulations across a diverse range of lipid compositions and therapeutic payloads with minimal supervision.
  • Apply hands-on expertise in LNP analytical characterization techniques, including RiboGreen assays, DLS, NanoFCM, NTA, TFF, endotoxin testing, and HPLC, as well as molecular biology methods such as DNA/RNA extraction, ELISA, SDS-PAGE, PCR, and Western blotting.
  • Generate high-quality, reproducible datasets and maintain accurate, detailed experimental documentation in electronic laboratory notebooks (ELNs).
  • Perform mammalian cell culture and support in vitro studies, including transient transfection and electroporation in established cell lines. Collaborate cross-functionally with process development, analytical, and in vivo teams to support reproducible manufacturing processes and advance programs toward clinical development.
  • Contribute to platform innovation by investigating LNP mechanisms of action to improve delivery efficiency, therapeutic potency, and formulation stability.
  • Present experimental results, technical findings, and project updates to cross-functional teams and broader organizational audiences.
  • Effectively manage multiple priorities and projects in a fast-paced, highly collaborative research environment.

Minimum Qualifications
  • BS or MS in Chemistry, Chemical Engineering, Biochemistry, or a related scientific discipline.
  • Relevant industry or academic research experience:
    • Research Associate II: 2-5+ years with a bachelor's degree or 0-2+ years of relevant experience with a master's degree
  • Hands-on experience in lipid nanoparticle (LNP) formulation and analytical characterization for nucleic acid and targeted delivery applications.
  • Strong understanding of drug delivery systems and gene editing therapeutics.
  • Demonstrated ability to work independently while contributing effectively within a fast-paced, results-driven, and collaborative research environment.
  • Highly organized with strong scientific rigor, problem-solving skills, and attention to detail.

Preferred Qualifications
  • Experience with high-throughput formulation screening and knowledge of microfluidic mixing process.
  • Prior experience of ionizable lipid design, bioconjugation, and process development preferred.
  • Prior experience with scale-up and large-scale manufacturability development of LNPs.
  • Understanding of RNA engineering, molecular biology, and hands-on experience of maintaining cells and performing in vitro transfection.

Competencies
  • Collaborative - Openness, One Team
  • Undaunted - Fearless, Can-do attitude
  • Results Orientation - Delivering progress toward our mission. Sense of urgency in solving problems.
  • Entrepreneurial Spirit - Proactive. Ownership mindset.

Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.
Research Associate II: Base pay range of $85,000 to $92,000 + discretionary bonus, equity and benefits.
The range provided is CRISPR Therapeutics' reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy

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