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Research Associate Downstream Process Development Jobs in Oregon

UNAVAILABLE

Senior Research Associate

Portland, OR · On-site

All of these topics are unified by the field of developmental biology and we use common molecular ... processes. We are looking for a Senior Research Associate who has extensive experience using ...

UNAVAILABLE

TI Clinical Research Associate

Portland, OR · On-site

The Float CRA may have direct patient contact, process biological samples and may perform other non ... TI Clinical Research Associate, represented by the Research Workers United (RWU), subject to the ...

Lam Research

Process Technician 1

Tualatin, OR · Hybrid

... development, and research and development (R&D). You'll set up processing equipment, conduct ... Associates degree in technical field, Technical Certificate, Diploma or higher in semiconductors ...

Lam Research

Process Technician 4

Tualatin, OR · Hybrid

... and development (R&D). You will set up processing equipment, conduct technical tests and ... Associates degree in technical field, Technical Certificate, Diploma or higher in semiconductors ...

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Research Associate Downstream Process Development information

What is a research associate downstream process development?

A Research Associate in Downstream Process Development works within biotechnology or pharmaceutical companies to optimize and scale up the purification and recovery of biological products, such as proteins or antibodies, after initial production. They focus on processes like filtration, chromatography, and centrifugation to ensure product quality and yield. These professionals design experiments, analyze data, and support the transfer of processes from laboratory scale to manufacturing. Their work is crucial for developing efficient, reproducible, and regulatory-compliant methods for producing biopharmaceuticals.

What are the key skills and qualifications needed to thrive as a research associate in downstream process development?

To thrive as a Research Associate in Downstream Process Development, you need a solid background in biochemistry, molecular biology, or chemical engineering, often demonstrated by a bachelor's or master's degree in a related field. Familiarity with chromatography systems (such as AKTA), filtration technologies, and Good Manufacturing Practice (GMP) standards, along with data analysis software, is typically required. Strong problem-solving skills, attention to detail, and effective teamwork and communication abilities help individuals excel in this role. These competencies are crucial for ensuring efficient, scalable purification processes and maintaining product quality in biopharmaceutical development.

What are the typical challenges faced by a research associate in downstream process development, and how can they be addressed?

A Research Associate in Downstream Process Development often encounters challenges such as optimizing purification processes for new biologics, troubleshooting equipment issues, and ensuring scalability from laboratory to production scale. Effective communication with cross-functional teams, such as upstream scientists and analytical specialists, is essential to resolve issues quickly. Staying current with new purification technologies and maintaining meticulous documentation can also help address these challenges and support successful process development.

What is the difference between Research Associate Downstream Process Development vs Research Associate Upstream Process Development?

AspectResearch Associate Downstream Process DevelopmentResearch Associate Upstream Process Development
Primary FocusPurification, filtration, chromatography of bioproductsCell culture, media optimization, bioreactor operation
Skills & CertificationsProtein purification, chromatography techniques, GMP complianceCell culture, aseptic techniques, bioreactor handling
Work EnvironmentLaboratory, manufacturing, quality controlLaboratory, bioprocessing facilities
Industry UsageBiopharmaceutical manufacturing, biotech researchBiopharmaceutical development, biotech research

While both roles support bioprocess development, Research Associate Downstream Process Development focuses on purification and filtration of bioproducts, whereas Research Associate Upstream Process Development emphasizes cell culture and bioreactor processes. Understanding these differences helps candidates align their skills with the appropriate role in biopharmaceutical production.

What cities in Oregon are hiring for Research Associate Downstream Process Development jobs?

Cities in Oregon with the most Research Associate Downstream Process Development job openings:

Research Associate Downstream Process Development jobs near you
Infographic showing various Research Associate Downstream Process Development job openings in Oregon as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 78% Full Time, 18% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution.

Research Associate

Portland, OR • On-site

Oregon Health & Science University
Colleges, Universities, and Professional Schools • 10K+ employees
Learn more about Oregon Health & Science Universityexternal

Full-time

Re-posted 10 days ago

Oregon Health & Science University rating

8.1

Company rating: 8.1 out of 10

Based on 95 frontline employees who took The Breakroom Quiz

Job description

Department OverviewFunction/Duties of Position

The lab of Stephen Back, M.D., Ph.D. at Oregon Health & Science University is seeking a Research Associate for studies of the effects of fetal and neonatal intermittent cerebral hypoxemia on brain development.  The lab currently has NIH funding for studies to explore the sequelae of maternal sleep apnea on fetal and postnatal brain development.  Despite the fact that maternal sleep apnea commonly occurs in roughly 20-40% of human pregnancies, the long-term impact on brain development and neurobehavior is unknown.  Studies are currently underway in a fetal sheep model to understand the effects of maternal intermittent hypoxia using a multidisciplinary approach that utilizes high field ex vivo MRI, hippocampal electrophysiology and neurona morphology.  All of these approaches are well established in the lab (see for example: Sci Transl Med 5(168):168ps2, 2013; Journal of Neuroscience, 39(40):7853-7871, 2019). 

This ideal candidate for this position will have direct experience with sheep including monitoring the health and well-being of the animals. Some maternal or fetal surgical experience is ideal but is not required. The project will involve two phases.  Experimental studies involve the delivery of a well-tolerated maternal mild hypoxia protocol in pregnant ewes, which is established in the lab, and includes monitoring of maternal oxygenation by pulse oximetry to validate the physiological response to hypoxia. Experience with the computer assisted acquisition and analysis of physiological data is preferred.

Required Qualifications
  • Master's Degree in relevant field AND 3 years of relevant experience OR Bachelor's Degree in relevant field AND 5 years of relevant experience.
  • Direct experience with sheep including monitoring the health and well-being of the animals.
  • The successful candidate will work in a lab setting and must have good communication skills, excellent recordkeeping and computer skills; and possess the ability to work independently while functioning within a team environment.
  • Excellent organizational skills, be enthusiastic about their work, and be highly motivated to succeed in a multi-disciplinary/multi-collaborator setting that provides a wealth of opportunities in one of the major universities for neuroscience research in the U.S.
Preferred Qualifications
  • Maternal or fetal surgical experience is ideal.
  • Experience with the computer assisted acquisition and analysis of physiological data is preferred.
Additional Details

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Upload cover letter and resume.  Please be sure to include months and years (MM/YYYY format) to the resume for jobs/work experience.

*OHSU Employees be sure to apply using your OHSU email*

Why apply to OHSU?We are Oregon's only public academic health center. In addition to caring for patients, we lead groundbreaking research. We also train the next generation of health care professionals. As Portland's largest employer, we give you opportunities to learn and advance in a system of hospitals and clinics across Oregon and Southwest Washington. All are welcome. OHSU welcomes people of all ages, ethnicities, genders, national origins, religions and sexual orientations. We are striving to build an anti-racist, multicultural institution and encourage people with diverse backgrounds to apply. To request reasonable accommodation, contact askhr@ohsu.eduEmployment Type: OTHER

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About Oregon Health & Science University

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Oregon Health & Science University (OHSU) is a distinguished institution under the industry of higher education and healthcare, specifically in the field of medical science. Based in Portland, Oregon, US, it maintains a reputation for promoting research, teaching, patient care, and outreach. Established in 1887, OHSU has continually sought to redefine the parameters of healthcare delivery and biomedical discovery through its expansive catalog of programs and initiatives. A galvanizing mission drives OHSU: to improve the health and quality of life for all Oregonians through excellence, innovation, and leadership in health care, education, and research.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Portland, OR, US

Year founded

1887

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