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Research Associate Downstream Process Development Jobs in Portland, OR

The Research Associate will provide professional, substantive, technical, and administrative ... Manage data collection, transfers, and quality control processes. * Ensure data integrity and ...

Research Associate

Portland, OR · On-site

$60 - $80/hr

Assists with non-AIRC Research Faculty study protocol development. Assists with instrument ... Work with AIRC faculty/staff to process and analyze data. * Help with user communication and ...

The Research Associate will provide professional, substantive, technical, and administrative ... Manage data collection, transfers, and quality control processes. * Ensure data integrity and ...

The Research Associate will provide professional, substantive, technical, and administrative ... Manage data collection, transfers, and quality control processes. * Ensure data integrity and ...

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Research Associate Downstream Process Development information

See Portland, OR salary details

$20

$35

$52

How much do research associate downstream process development jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for research associate downstream process development in Portland, OR is $35.72, according to ZipRecruiter salary data. Most workers in this role earn between $29.33 and $43.85 per hour, depending on experience, location, and employer.

What is a research associate downstream process development?

A Research Associate in Downstream Process Development works within biotechnology or pharmaceutical companies to optimize and scale up the purification and recovery of biological products, such as proteins or antibodies, after initial production. They focus on processes like filtration, chromatography, and centrifugation to ensure product quality and yield. These professionals design experiments, analyze data, and support the transfer of processes from laboratory scale to manufacturing. Their work is crucial for developing efficient, reproducible, and regulatory-compliant methods for producing biopharmaceuticals.

What are the key skills and qualifications needed to thrive as a research associate in downstream process development?

To thrive as a Research Associate in Downstream Process Development, you need a solid background in biochemistry, molecular biology, or chemical engineering, often demonstrated by a bachelor's or master's degree in a related field. Familiarity with chromatography systems (such as AKTA), filtration technologies, and Good Manufacturing Practice (GMP) standards, along with data analysis software, is typically required. Strong problem-solving skills, attention to detail, and effective teamwork and communication abilities help individuals excel in this role. These competencies are crucial for ensuring efficient, scalable purification processes and maintaining product quality in biopharmaceutical development.

What are the typical challenges faced by a research associate in downstream process development, and how can they be addressed?

A Research Associate in Downstream Process Development often encounters challenges such as optimizing purification processes for new biologics, troubleshooting equipment issues, and ensuring scalability from laboratory to production scale. Effective communication with cross-functional teams, such as upstream scientists and analytical specialists, is essential to resolve issues quickly. Staying current with new purification technologies and maintaining meticulous documentation can also help address these challenges and support successful process development.

What is the difference between Research Associate Downstream Process Development vs Research Associate Upstream Process Development?

AspectResearch Associate Downstream Process DevelopmentResearch Associate Upstream Process Development
Primary FocusPurification, filtration, chromatography of bioproductsCell culture, media optimization, bioreactor operation
Skills & CertificationsProtein purification, chromatography techniques, GMP complianceCell culture, aseptic techniques, bioreactor handling
Work EnvironmentLaboratory, manufacturing, quality controlLaboratory, bioprocessing facilities
Industry UsageBiopharmaceutical manufacturing, biotech researchBiopharmaceutical development, biotech research

While both roles support bioprocess development, Research Associate Downstream Process Development focuses on purification and filtration of bioproducts, whereas Research Associate Upstream Process Development emphasizes cell culture and bioreactor processes. Understanding these differences helps candidates align their skills with the appropriate role in biopharmaceutical production.

Infographic showing various Research Associate Downstream Process Development job openings in Portland, OR as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 79% Full Time, 17% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $74,300 per year, or $35.7 per hour.

Advanced Packaging Photolithography Development Engineer

Hillsboro, OR • Hybrid

Intel
Manufacturing • 10K+ employees

$133K - $188K/yr

Full-time

Medical, Retirement, PTO

Posted 28 days ago


Intel rating

8.7

Company rating: 8.7 out of 10

Based on 147 frontline employees who took The Breakroom Quiz

19th of 162 rated electronics manufacturers


Job description

Job Details:Job Description: 

We are seeking a highly skilled and motivated Lithography Process Development Engineer to join our Advanced Packaging Technology Development team. In this role, you will be driving lithography process development at the forefront of next-generation semiconductor packaging technology, including hybrid bonding applications. You will work in a dynamic, cross-functional environment collaborating with process integration, equipment, metrology, and design teams to enable industry-leading interconnect density and yield.
Key Responsibilities


Qualify scanner/stepper platforms and Track system for backend and hybrid bonding lithography applications
Develop, characterize, and optimize photolithography processes for back-end applications, including Cu damascene pad patterning, dielectric via and trench lithography, bonding interface layer patterning, and alignment mark / overlay target design and optimization
Evaluate and implement underlayer stacks to address topography challenges inherent in far backend and packaging substrates
Develop and optimize overlay metrology and control strategies critical for advanced packaging nodes
Implement advanced process control (APC) including run-to-run (R2R) and lot-to-lot overlay feedback/feedforward control loops
Work closely with integration and other modules to develop fully integrated process flows, ensuring lithography compatibility with upstream and downstream process steps
Support yield learning by performing systematic defect analysis, root cause investigation, and implementing corrective actions for lithography-related yield detractors
Contribute to technology roadmap planning for next-generation node and engage with equipment and material suppliers to evaluate next-generation tools and materials

Qualifications:

Minimum qualifications are required to be initially considered for this position. Preferred qualifications are in addition to the minimum requirements and are considered a plus factor in identifying top candidates.

Minimum Qualifications


- Master's degree in Materials Science and Engineering, Mechanical Engineering, Chemical Engineering, Electrical Engineering, Physics, Chemistry, or related fields with 3+ years of relevant experience
- PhD degree in the same fields with 2+ years of relevant experience

Experience listed above should be a combination of the following:


- Hands-on lithography process development experience with i-line, KrF or ArF lithography process development in a semiconductor fab
- Hands-on experience with photoresist process development, including coat/bake/develop optimization, resist profile engineering, and process window characterization
- Strong understanding of optical lithography fundamentals: aerial image formation, resist chemistry, focus-exposure matrix (FEM), depth of focus (DOF), and exposure latitude (EL)
- Proficiency in Statistical Process Control (SPC) and Design of Experiments (DOE) principles.
Preferred Qualifications


- Strong analytical and problem-solving skills with ability to perform systematic root cause analysis on complex, multi-variable process issues
- Experience with packaging processes, equipment automation development, or project management in technology development.
- Experience in advanced packaging lithography environments (Foveros, Foveros Direct, fan-out WLP, 2.5D/3D IC, CoWoS, SoIC, or equivalent)

- Experience with overlay metrology and control, and familiarity with CDSEM and OCD/scatterometry for process monitoring and control
We look forward to welcoming passionate and driven individuals who want to work on transformative projects and play a crucial role in shaping the future of semiconductor technology. Take this opportunity to bring your unique skills to Intel and make an impact-apply today.

Job Type:Experienced HireShift:Shift 1 (United States of America)Primary Location: US, Oregon, HillsboroAdditional Locations:Posting Statement:All qualified applicants will receive consideration for employment without regard to race, color, religion, religious creed, sex, national origin, ancestry, age, physical or mental disability, medical condition, genetic information, military and veteran status, marital status, pregnancy, gender, gender expression, gender identity, sexual orientation, or any other characteristic protected by local law, regulation, or ordinance.Position of TrustN/ABenefits

We offer a total compensation package that ranks among the best in the industry. It consists of competitive pay, stock bonuses, and benefit programs which include health, retirement, and vacation. Find out more about the benefits of working at Intel.

Annual Salary Range for jobs which could be performed in the US: $133,800.00-188,890.00 USDThe range displayed on this job posting reflects the minimum and maximum target compensation for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. Your recruiter can share more about the specific compensation range for your preferred location during the hiring process.

Work Model for this Role

This role will require an on-site presence. * Job posting details (such as work model, location or time type) are subject to change.

*

ADDITIONAL INFORMATION: Intel is committed to Responsible Business Alliance (RBA) compliance and ethical hiring practices. We do not charge any fees during our hiring process. Candidates should never be required to pay recruitment fees, medical examination fees, or any other charges as a condition of employment. If you are asked to pay any fees during our hiring process, please report this immediately to your recruiter.

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About Intel

Sourced by ZipRecruiter

Intel strives to make every facet of semiconductor manufacturing state-of-the-art -- from semiconductor process development and manufacturing, through yield improvement to packaging, final test and optimization, and world class Supply Chain and facilities support. Employees in the Technology and Manufacturing Group are part of a worldwide network of design, development, manufacturing, and assembly/test facilities, all focused on utilizing the power of Moore's Law to bring smart, connected devices to every person on Earth

Industry

Manufacturing

Company size

10,000+ Employees

Headquarters location

Santa Clara, CA, US

Year founded

1968