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Remote Typescript Developer Jobs in Massachusetts

Lead Software Engineer

Watertown, MA · On-site +1

$150K - $180K/yr

Our tech stack includes React, React Native, Typescript, Python, Django, Postgres, Docker, and AWS ... Our office is in Watertown, Massachusetts, but we've developed a robust remote working structure to ...

$133K - $175K/yr

With JavaScript systems (Redux, React, TypeScript, Next.js, etc.). * Experience with networked ... Generate is remote work first, but we are also willing to discuss relocation to Boston ...

Senior Solutions Architect

Boston, MA · Remote

$130K - $160K/yr

Remote - United States Job Type: Full-Time, Permanent About Exemplar Companies Exemplar Companies ... Proficiency with JavaScript, TypeScript, React, Next.js, and Node.js. * Experience integrating ...

Senior Full Stack Engineer

Boston, MA · On-site +1

$120K - $160K/yr

JavaScript → TypeScript) to improve reliability, safety, and long-term maintainability. * Own ... Equity Owl Labs is a hybrid company, we are over 40% remote, and our headquarters is based in ...

Senior Full Stack Engineer

Somerville, MA · On-site +1

$120K - $160K/yr

JavaScript → TypeScript) to improve reliability, safety, and long-term maintainability. * Own ... Equity Owl Labs is a hybrid company, we are over 40% remote, and our headquarters is based in ...

Senior Full Stack Engineer

Cambridge, MA · On-site +1

$120K - $160K/yr

JavaScript → TypeScript) to improve reliability, safety, and long-term maintainability. * Own ... Equity Owl Labs is a hybrid company, we are over 40% remote, and our headquarters is based in ...

Senior Software Engineer

Boston, MA · On-site +1

$120K - $150K/yr

You know modern front-end tools (HTML, CSS, JavaScript/Typescript, React/Svelte/Solid, etc.) and ... Flexible work environment with remote opportunities * Hybrid work schedule * Company provided ...

Senior Staff Software Engineer, Platform

Boston, MA · On-site +1

$133K - $175K/yr

... Typescript, Node, GraphQL, and SQL (amongst others), while leveraging full CI and CD to iterate ... US - Remote Compensation & Benefits * Base Salary: The range listed above reflects our standard pay ...

Showing results 41-59

Remote Typescript Developer information

What are the key skills and qualifications needed to thrive as a remote Typescript developer, and why are they important?

To thrive as a Remote Typescript Developer, you need strong proficiency in Typescript, JavaScript, and web development frameworks, typically supported by a degree in computer science or related experience. Familiarity with version control systems like Git, cloud platforms such as AWS or Azure, and modern development tools like Node.js and React is usually expected. Excellent problem-solving skills, self-motivation, and effective remote communication are standout soft skills in this role. These capabilities are crucial for delivering reliable, scalable software solutions and collaborating efficiently in distributed teams.

What does a remote Typescript developer do?

A Remote Typescript Developer is a software engineer who specializes in using the TypeScript programming language to build and maintain web applications, often from a location outside of a traditional office. Their responsibilities typically include writing clean, scalable code, collaborating with other team members via online tools, debugging, and ensuring applications are robust and maintainable. They may work on both front-end and back-end technologies, often using frameworks like React, Angular, or Node.js. Communication, self-management, and proficiency in remote collaboration tools are essential skills for this role.

How does a remote Typescript developer typically collaborate with distributed teams on large-scale projects?

Remote Typescript Developers usually work closely with cross-functional teams through digital collaboration tools such as Slack, Jira, and GitHub. Communication is key, as developers participate in daily stand-ups, code reviews, and sprint planning meetings to ensure alignment on project goals and coding standards. Effective remote collaboration also involves maintaining clear documentation, proactively sharing updates, and using version control systems to manage code contributions. This structure supports teamwork and helps resolve challenges like time zone differences and asynchronous communication.
What are the most commonly searched types of Typescript Developer jobs in Massachusetts? The most popular types of Typescript Developer jobs in Massachusetts are:
What job categories do people searching Remote Typescript Developer jobs in Massachusetts look for? The top searched job categories for Remote Typescript Developer jobs in Massachusetts are:
What cities in Massachusetts are hiring for Remote Typescript Developer jobs? Cities in Massachusetts with the most Remote Typescript Developer job openings:
Infographic showing various Remote Typescript Developer job openings in Massachusetts as of August 2026, with employment types broken down into 82% Full Time, 4% Part Time, and 14% Contract. Highlights an 80% Physical, 6% Hybrid, and 14% Remote job distribution.

Principal Software Engineer

eClinical Solutions

Mansfield, MA • On-site, Remote

$142K - $191K/yr

Full-time

Re-posted 5 days ago


Job description

About eClinical Solutions
eClinical Solutions is transforming clinical development with elluminate®, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle-accelerating innovation that ultimately improves patient outcomes.
Our engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you're excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.
You will make an impact:
As a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team. You'll help design and build the core services and user experiences of a next-generation clinical data and analytics platform-while influencing architecture, engineering standards, and technical direction.
This role is ideal for an experienced engineer who enjoys hands-on development, mentoring others, and bringing modern capabilities-including AI-assisted and agentic workflows-into production-grade systems.
Your day to day:
  • Design, develop, test, and deploy scalable, secure, and highly interactive web applications
  • Own and evolve core platform modules, from concept through release and support
  • Influence application and system architecture with a focus on performance, reliability, security, and maintainability
  • Lead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions
  • Collaborate closely with Product Management, QA, and other engineers throughout the SDLC
  • Provide technical mentorship and guidance to other engineers on the team
  • Diagnoses and resolves complex production issues across distributed systems
  • Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations
  • Contribute to technical documentation including design specs, acceptance criteria, and release notes

AI & Modern Engineering Focus
We're actively incorporating AI-powered capabilities into our platform, and you'll help shape how this is done responsibly and effectively in an enterprise environment. This includes:
  • Integrating LLMs and AI services into .NET- and Python-based systems
  • Designing and implementing AI-assisted workflows, copilots, or intelligent automation features
  • Working with agentic AI patterns (e.g., task orchestration, tool-using agents, workflow automation)
  • Applying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance
  • Collaborating with data and platform teams to operationalize AI-not just prototype it

Deep ML expertise is not required-we're looking for strong engineers who understand how to apply AI capabilities in real products.
Take the first step toward your dream career. Here is what we are looking for in this role.
Qualifications:
  • Bachelor's or Master's degree in Computer Science or equivalent practical experience
  • 10+ years in software design and development using the Microsoft technology stack preferred
  • Expert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs)
  • Strong experience building full-stack web applications (Angular, TypeScript, HTML, CSS)
  • Solid understanding of software design principles, patterns, and best practices
  • Experience across the full Software Development Lifecycle (Agile preferred)
  • Proven ability to work independently while collaborating effectively in a fast-paced environment
  • Excellent communication, documentation, and technical leadership skills

AI & Platform Experience
  • Hands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications
  • Experience using Python and/or .NET alongside AI/LLM workflows
  • Familiarity with agent-based or workflow-driven AI architectures is a strong plus
  • Understanding of secure and responsible AI usage in enterprise systems

Nice to Have
  • Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning
  • Experience with microservices, distributed systems, and cloud platforms (AWS preferred)
  • Secure development experience, including awareness of common vulnerabilities and mitigations
  • Experience with clinical trial data, life sciences, or regulated SaaS environments
  • Experience building data visualizations or analytics-driven user experiences

Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!
eClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: https://topworkplaces.com/company/eclinical-solutions/
eClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here!
We are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.
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Pay Range
US Pay Ranges
$152,000-$190,000 USD