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Remote Principal Investigator Jobs (NOW HIRING)

Care Access

Travel Sub-Investigator

$47K - $48K/yr

Work closely with the Principal Investigator to oversee the execution of study protocols ... Remote within the United States. This is an on-site mixed with remote tele-medicine work position.

Merjent

Staff Archaeologist - Remote

Milwaukee, WI · Remote

$72K - $94K/yr

The Staff Archaeologist/Principal Investigator is responsible for performing common tasks ... Merjent has staff located across the United States who may choose a remote, in-office, or hybrid ...

Merjent

Staff Archaeologist - Remote

Milwaukee, WI · On-site +1

$72K - $94K/yr

The Staff Archaeologist/Principal Investigator is responsible for performing common tasks ... Merjent has staff located across the United States who may choose a remote, in-office, or hybrid ...

Emory University

Post Doctoral Fellow - Dr. Yan Sun

Atlanta, GA · On-site +1

$47K - $64K/yr

Prepares and publishes scientific manuscripts under the direction of the Principal Investigator ... Emory reserves the right to change remote work status with notice to employee. Additional Details ...

Emory University

Post Doctoral Fellow - Epidemiology

Atlanta, GA · On-site +1

$47K - $64K/yr

Work closely with the Principal Investigator in all aspects of the research. * Lead and collaborate ... Emory reserves the right to change remote work status with notice to employee. Additional Details ...

The Pennsylvania State University

Approval of remote and hybrid work is not guaranteed regardless of work location.For additional ... Engage with Principal Investigators (PIs) and engineering and technical task teams to translate ...

Yale University

Senior Regulatory Analyst - Yale IRB

$118K - $119K/yr

... serve as a Principal Investigator for studies submitted for review. 6. Evaluate and analyze ... Remote Background Check Requirements All candidates for employment will be subject to pre ...

USAA

SIU Investigator Intermediate - Field

Los Angeles, CA · On-site +1

$77K - $147K/yr

USAA roles may offer remote or hybrid flexibility for active-duty military spouses consistent with ... The above description reflects the details considered necessary to describe the principal functions ...

USAA

SIU Investigator Intermediate - Field

Los Angeles, CA · On-site +1

$77K - $147K/yr

USAA roles may offer remote or hybrid flexibility for active-duty military spouses consistent with ... The above description reflects the details considered necessary to describe the principal functions ...

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All JobsRemote Principal Investigator Jobs

Remote Principal Investigator information

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$19.5K

$142.7K

$260.5K

How much do remote principal investigator jobs pay per year?

As of Jun 17, 2026, the average yearly pay for remote principal investigator in the United States is $142,668.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,000.00 and $200,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Remote Principal Investigator, and why are they important?

To thrive as a Remote Principal Investigator, you need advanced research expertise, a relevant doctoral degree (such as a PhD or MD), and a track record in leading scientific studies. Familiarity with research management software, electronic data capture systems, and regulatory compliance tools (like IRB submission platforms) is typically required. Strong leadership, project management, and effective communication skills help you coordinate distributed teams and stakeholders remotely. These capabilities ensure rigorous, compliant research execution and successful project outcomes across virtual environments.

What is a Remote Principal Investigator?

A Remote Principal Investigator is a lead researcher who oversees and manages scientific studies or research projects from a remote location, rather than being physically present at the study site. They are responsible for designing the research, ensuring compliance with regulations, managing data collection, and supervising team members virtually. This role has become more common with the advancement of digital collaboration tools, allowing PIs to effectively conduct and monitor research projects from anywhere. Remote PIs still maintain accountability for the integrity and outcomes of their studies.

What is the difference between Remote Principal Investigator vs Remote Research Coordinator?

AspectRemote Principal InvestigatorRemote Research Coordinator
Required credentialsAdvanced degrees (PhD, MD), research experience, often certificationsBachelor's or Master's degree, research training
Work environmentLeads research projects, oversees study design, data analysisSupports project logistics, manages schedules, assists with data collection
Employer and industry usageUniversities, research institutions, pharmaceutical companiesResearch organizations, clinical trial sites, academic labs
Search and comparison intentUnderstanding leadership roles in researchSupporting research activities and coordination

The Remote Principal Investigator typically leads research projects, requiring advanced credentials and overseeing study execution. In contrast, a Remote Research Coordinator supports the research process by managing logistics and data collection. Both roles are essential in research settings but differ in responsibilities and qualifications.

What are the unique challenges of managing a research team as a Remote Principal Investigator?

As a Remote Principal Investigator, one of the key challenges is maintaining effective communication and collaboration among team members who may be working from different locations and time zones. Coordinating virtual meetings, ensuring alignment on research objectives, and fostering a sense of team cohesion can require more proactive effort than in traditional in-person settings. Additionally, overseeing project progress and ensuring compliance with research protocols remotely demands strong organizational and leadership skills. Utilizing collaboration tools and establishing clear communication protocols are vital for success in this role.
What cities are hiring for Remote Principal Investigator jobs? Cities with the most Remote Principal Investigator job openings:
What are the most commonly searched types of Principal Investigator jobs? The most popular types of Principal Investigator jobs are:
What states have the most Remote Principal Investigator jobs? States with the most job openings for Remote Principal Investigator jobs include:
Remote Principal Investigator jobs near you
Travel Sub-Investigator

Travel Sub-Investigator

Care Access

Remote

$47K - $48K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 4 days ago

Job description

About Care Access
Care Access is working to make the future of health better for all. With hundreds of research locations, mobile clinics, and clinicians across the globe, we bring world-class research and health services directly to communities that often face barriers to care. We are dedicated to ensuring that every person has the opportunity to understand their health, access the care they need, and contribute to the medical breakthroughs of tomorrow.
With programs like Future of Medicine, which makes advanced health screenings and research opportunities accessible to communities worldwide, and Difference Makers, which supports local leaders to expand their community health and wellbeing efforts, we put people at the heart of medical progress. Through partnerships, technology, and perseverance, we are reimagining how clinical research and health services reach the world. Together, we are building a future of health that is better and more accessible for all.
To learn more about Care Access, visit www.CareAccess.com.
How This Role Makes a Difference
The Sub-Investigator will be responsible for travel mixed with remote tele-medicine work to support our clinical research studies. Additionally, our Sub-Investigator will be skilled in administering investigational products (IV, SC, TD, IM, PO administration), performing physical examinations, monitoring for investigational product related reactions, among other duties beyond the standard clinical research Sub-Investigator role. Care Access is looking for highly motivated Nurse Practitioners or Physician's Assistants to support clinical trial related activities in states throughout the USA.
How You'll Make An Impact
  • Work closely with the Principal Investigator to oversee the execution of study protocols, delegating study related duties to site staff, as appropriate, and ensuring site compliance with study protocols, study-specific laboratory procedures, standards of Good Clinical Practice (GCP), Standard Operating Procedures (SOPs), quality (QA/QC) procedures, OSHA guidelines, and other state and local regulations as applicable.
  • Attends and participates in meetings with the director, other managers, and staff as necessary.
  • Complies with regulatory requirements, policies, procedures, and standards of practice.
  • Read and understand the informed consent form, protocol, and investigator's brochure.
  • Be available to see subjects virtually or in-person as dictated by project design, answer their questions, and resolve medical issues during the study visit.
  • Sign and ensure that the study documentation for each study visit is completed.
  • Perform all study responsibilities in compliance with the IRB approved protocol.
  • Administration of Investigational Products (via subcutaneous, transdermal, intramuscular, intravenous, or oral routes).
  • Proficiency in starting, monitoring, and maintaining intravenous lines.
  • Proficiency in phlebotomy, proper blood collection practices, and laboratory processing practices (can be learned)
  • Contribute as an active member of clinician team involved in the management of infusion or other investigational product related reactions.
  • Maintain a clean, efficient clinical area to assure the highest standards of patient care.
  • Follow safety and PPE procedures as well as maintain proper documentation of infusion procedures.
  • Timely communications with internal teams, investigators, review boards, and study subjects
  • Perform trial procedures as per delegation which can include the following but not limited to:
  • Prescreen study candidates by telephone and review exclusionary conditions or medications prior to scheduling screening appointment.
  • Obtain informed consent per SOP.
  • Administer delegated study questionnaires, as appropriate.
  • Collect and evaluate medical records.
  • Complete visit procedures and ensure proper specimen collection, processing, and shipment in accordance with protocol.
  • Train others and complete basic clinical procedures, such as blood draws, vital signs, ECGs, etc.
  • Review screening documentation and approves subjects for admission to study.
  • Review admission documentation and approves subject for randomization.
  • Provide ongoing assessment of the study subject/patient to identify Adverse Events.
  • Ensure that serious and unexpected adverse events are reported promptly to the Pl.
  • Review and evaluates all study data and comments to the clinical significance of any out-of-range results.
  • Perform physical examinations as part of screening evaluation and active study conduct.
  • Provide medical management of adverse events as appropriate.
  • Dispense study medication per protocol and/or IVRS systems. Educate patient on proper administration and importance of compliance.
  • Monitor patient progress on study medication.
  • Other duties as assigned.

The Expertise Required
  • Ability to check, perform, and document vitals as well as EKG (ECG)
  • Phlebotomy and expert IV skills
  • Excellent working knowledge of medical and research terminology
  • Excellent working knowledge of federal regulations, good clinical practices (GCP)
  • Ability to communicate and work effectively with a diverse team of professionals.
  • Strong organizational skills: Able to prioritize, support, and follow through on assignments with good understanding of medical terminology.
  • Communication Skills: Strong verbal and written communication skills as evidenced by positive interactions with coworkers, management, clients and vendors.
  • Communication Skills: Strong verbal and written communication skills as evidenced by positive interactions with coworkers, management, clients and vendors.
  • Team Collaboration Skills: Work effectively and collaboratively with other team members to accomplish mutual goals. Bring positive and supportive attitude to achieving these goals.
  • Strong computer skills with demonstrated abilities using clinical trials database, IVR systems, electronic data capture, MS word and excel.
  • Ability to balance tasks with competing priorities.
  • Critical thinker and problem solver.
  • Curiosity and passion to learn, innovative, and able to take thoughtful risks while communicating concerns and mitigations.
  • Good management and organizational skills, understanding of medical procedures.
  • Exceptional interpersonal skills, willingness to the ability to work independently.
  • Ability to lift a minimum of 50 pounds.
  • Command of professional and Business English (written and spoken).
  • You must have the authorization to work in the US for any employer.
  • You must not need visa sponsorship, either now or in the future.
  • You must live in the USA and be willing and able to travel with 24-36-hour notice

Certifications/Licenses, Education, and Experience:
  • At least Master's Level Science Degree. Nurse Practitioner or Physician Assistant with 5+ years of clinical experience.
  • Clinical practice experience desired with infusion skillset.
  • Currently licensed in good standing in one or more states.
  • A minimum of 1 year of relevant work experience as Sub-Investigator (preferred) in a Clinical Research setting.
  • Preferred at least one (1) year of experience as a Clinical Research Coordinator or willingness to learn.

How We Work Together
  • Location: Remote within the United States. This is an on-site mixed with remote tele-medicine work position.
  • Travel: Regional and nationwide travel requirements up to 100% dependent on project design and business need. Regularly planned travel will be required as part of the role.
  • Physical demands associated with this position Include: The ability to use keyboards and other computer equipment.

The expected salary range for this role is $130,000 - $165,000 USD per year for full time team members.
Benefits & Perks (US Full Time Employees)
  • Paid Time Off (PTO) and Company Paid Holidays
  • 100% Employer paid medical, dental, and vision insurance plan options
  • Health Savings Account and Flexible Spending Accounts
  • Bi-weekly HSA employer contribution
  • Company paid Short-Term Disability and Long-Term Disability
  • 401(k) Retirement Plan, with Company Match

Diversity & Inclusion
We work with and serve people from diverse cultures and communities around the world. We are stronger and better when we build a team representing the communities we support. We maintain an inclusive culture where people from a broad range of backgrounds feel valued and respected as they contribute to our mission.
We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to, and will not be discriminated against on the basis of, race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.
Care Access is unable to sponsor work visas at this time.
If you need an accommodation to apply for a role with Care Access, please reach out to: TalentAcquisition@careaccess.com
Mandatory Employer Disclosures:
Notice to Illinois applicants: Applicants are not obligated to disclose expunged juvenile records or adjudication, arrest, or conviction.
Notice to Connecticut applicants: Care Access may require applicants to submit to a urinalysis drug test in connection with an application for employment.
Notice to Arizona, Georgia, Indiana, and North Dakota applicants: Care Access complies with applicable laws prohibiting smoking in and around places of employment.
Notice to Massachusetts applicants: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Notice to Rhode Island applicants: Care Access complies with Rhode Island law prohibiting smoking in enclosed areas within places of employment. Care Access is also subject to is subject to Chapters 29-38 of Title 28 of the Rhode Island General Laws.
Notice to Maryland applicants: UNDER MARYLAND LAW, AN EMPLOYER MAY NOT REQUIRE OR DEMAND, AS A CONDITION OF EMPLOYMENT, PROSPECTIVE EMPLOYMENT, OR CONTINUED EMPLOYMENT, THAT AN INDIVIDUAL SUBMIT TO OR TAKE A LIE DETECTOR OR SIMILAR TEST. AN EMPLOYER WHO VIOLATES THIS LAW IS GUILTY OF A MISDEMEANOR AND SUBJECT TO A FINE NOT EXCEEDING $100.

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