Remote Principal Engineer Jobs in Boston, MA (NOW HIRING)

Staff / Principal Engineer
Department: Advisory
Employment Type: Full Time
Location: US
Compensation: $163,547 - $185,000 / year
Description
Newfire Global Partners is a leading technology firm that specializes in building transformative software solutions for some of the world's most innovative companies. With a presence across four continents, Newfire Global brings deep expertise in digital healthcare, AI-driven analytics, and enterprise technology. The firm's track record of delivering scalable, high-impact solutions has made it a trusted partner for organizations seeking to drive meaningful change through technology.
We are passionate about the purpose-driven mission to help improve the quality of care for patients and are building a collaborative, innovative, and inclusive culture. We are a fully funded company founded by serial entrepreneurs with a stable client base.
Opportunity for impact
Newfire Global Partners, a leader in developing disruptive healthcare technology, collaborates with Fortune 500 companies and start-ups to drive transformation.
We are seeking an exceptional Staff or Principal Engineer to join our client's engineering leadership team. This is a senior individual contributor role for a technologist who thrives at the intersection of modern software engineering and artificial intelligence. The ideal candidate will bring deep full-stack expertise across C#, React, and Python, paired with a demonstrated ability to lead and champion AI-assisted development practices-spanning LLM integration, MLOps, prompt engineering, and AI-powered product features. Based in the US with a strong preference for East Coast availability, this engineer will set the technical direction for how AI amplifies our engineering teams and shapes our healthcare platform
Role & responsibilities
• Serve as a technical leader and trusted authority on AI-assisted engineering, driving adoption of Copilot, code generation, and LLM-powered tooling across the engineering organization.
• Architect and deliver AI-powered product features that improve healthcare outcomes-spanning intelligent automation, clinical decision support, and member-facing experiences.
• Design and implement LLM workflows and prompt engineering patterns, ensuring reliable, safe, and scalable AI integrations in production environments.
• Lead MLOps initiatives including model deployment pipelines, monitoring, versioning, and lifecycle management in collaboration with data science teams.
• Build and maintain full-stack solutions using C# (.NET), React, and Python, with a strong focus on scalability, security, and maintainability.
• Define and evangelize engineering best practices for AI integration, code quality, and system design across Staff and Senior engineers.
• Collaborate with product, data, and clinical teams to identify high-impact opportunities for AI and machine learning in the healthcare domain.
• Conduct design reviews, architecture discussions, and hands-on code reviews to raise the technical bar across the organization.
• Mentor and grow senior engineers, fostering a culture of experimentation, ownership, and continuous learning.
• Stay at the forefront of rapidly evolving AI/ML tooling, evaluating and recommending emerging technologies relevant to the client
You're a Perfect Match If You Have:
• Deep proficiency in C# and .NET - including API design, microservices architecture, and enterprise-grade backend systems.
• Strong hands-on experience with React and modern front-end development patterns (TypeScript, component architecture, state management).
• Solid Python skills with practical experience in scripting, automation, data pipelines, or ML model integration.
• Proven experience integrating LLMs (e.g., OpenAI, Azure OpenAI, Anthropic) into production applications via APIs, SDKs, or orchestration frameworks such as LangChain or Semantic Kernel.
• Strong understanding of prompt engineering principles, RAG (Retrieval-Augmented Generation) patterns, and LLM evaluation strategies.
• Hands-on experience with MLOps tooling and practices - model versioning, deployment, monitoring, and retraining pipelines.
• Experience with AI-assisted development tools such as GitHub Copilot, Cursor, or equivalent, with the ability to coach teams on effective usage.
• Solid understanding of cloud infrastructure (Azure preferred) and how to architect scalable, secure AI-integrated systems.
• Strong command of software design principles - SOLID, clean architecture, domain-driven design, and API-first development.
• Experience with CI/CD pipelines, infrastructure as code, and DevOps practices in a cloud-native environment.
Optional / Plus
• Experience in healthcare technology, including knowledge of HL7, FHIR, or clinical data standards.
• Familiarity with vector databases (e.g., Pinecone, Weaviate, Azure AI Search) for embedding-based retrieval systems.
• Exposure to fine-tuning or customizing foundation models for domain-specific use cases.
• Knowledge of responsible AI practices, model explainability, and bias mitigation in healthcare contexts.
• Experience with data platforms such as Databricks, Snowflake, or Azure Synapse.
The Offer
Newfire Global is committed to consistent compensation practices across our organization. Total compensation for this role is market driven, with a salary of $163,547 - $185,000. Base pay is ultimately determined based on a candidate's skills, expertise, and experience. We also offer a comprehensive benefits package including medical, dental & vision coverage, health spending accounts, voluntary benefits, leave of absence policies, Employee Assistance Program, 401(k) program with employer contribution, Flexible work schedules and time-off policy, as well as company equipment for all new full-time US-based remote employees.
Offers are contingent upon successful completion of a background screening. Background screenings will be conducted in compliance with applicable laws and will not be initiated without your consent.
Newfire Global is an Equal Employment Opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, national origin, protected veteran status, disability status, sexual orientation, gender identity or expression, marital status, genetic information, or any other characteristic protected by law.