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Remote Modeling Simulation Engineer Jobs in Boston, MA

The work may involve both in-house "hands-on" development of models (de novo programming) as well ... Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be ...

System Concepts Engineer

Cambridge, MA · On-site +1

$82.30K - $220K/yr

Roles may require proficiency with modeling and simulation, computer language coding, descriptive modeling (e.g. SysML), STPA, and/or other engineering analysis tools * Knowledge of GN&C, avionics ...

System Concepts Engineer

Cambridge, MA · On-site +1

$82.30K - $220K/yr

Roles may require proficiency with modeling and simulation, computer language coding, descriptive modeling (e.g. SysML), STPA, and/or other engineering analysis tools Knowledge of GN&C, avionics ...

Mechanical Engineering Technical Leader

Boston, MA · On-site +1

$168.80K - $241.20K/yr

Meet the Team We are seeking a highly experienced and driven ASIC Mechanical Engineer to join the ... Define and establish simulation methodologies, modeling best practices, and correlation strategies ...

Lead Model-Based Systems Engineer

Woburn, MA · On-site +1

$157K - $224K/yr

The ideal candidate will be experienced in Systems Engineering processes and techniques, Modeling and Simulation, software-based systems, Digital Engineering/MBSE and be excited about opportunities ...

Lead Model-Based Systems Engineer

Woburn, MA · On-site +1

$157K - $224K/yr

The ideal candidate will be experienced in Systems Engineering processes and techniques, Modeling and Simulation, software-based systems, Digital Engineering/MBSE and be excited about opportunities ...

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Remote Modeling Simulation Engineer information

See Boston, MA salary details

$42.4K

$134.1K

$207K

How much do remote modeling simulation engineer jobs pay per year?

As of May 30, 2026, the average yearly pay for remote modeling simulation engineer in Boston, MA is $134,061.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,900.00 and $159,200.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Remote Modeling Simulation Engineer, and why are they important?

To thrive as a Remote Modeling Simulation Engineer, you need a solid background in engineering or computer science, strong mathematical modeling skills, and experience with simulation methodologies. Familiarity with tools like MATLAB, Simulink, Python, and simulation software, along with relevant certifications such as Certified Systems Engineering Professional (CSEP), is often required. Exceptional problem-solving, self-motivation, and clear communication are crucial soft skills, especially when collaborating remotely with diverse teams. These skills ensure accurate model development, effective virtual teamwork, and the delivery of reliable simulation results for complex engineering challenges.

How does a Remote Modeling Simulation Engineer typically collaborate with cross-functional teams despite working remotely?

Remote Modeling Simulation Engineers frequently work with multidisciplinary teams, including software developers, project managers, and subject matter experts. Collaboration is typically facilitated through virtual meetings, shared simulation platforms, and cloud-based project management tools. Regular communication and thorough documentation are essential to ensure alignment on project goals and simulation requirements. While remote work offers flexibility, it also requires proactive engagement to stay connected and effectively contribute to team-driven problem solving.

What are Remote Modeling Simulation Engineers?

Remote Modeling Simulation Engineers are professionals who use computer-based models and simulations to analyze, design, and optimize systems or products, often working from a location outside of a traditional office. They leverage specialized software to create virtual prototypes and run simulations, which helps in testing and improving designs without the need for physical experiments. These engineers collaborate with teams online, and their work is crucial in industries such as aerospace, automotive, energy, and manufacturing. Their remote setup allows companies to tap into a wider talent pool and offers professionals greater flexibility.

What is the difference between Remote Modeling Simulation Engineer vs Remote Data Analyst?

AspectRemote Modeling Simulation EngineerRemote Data Analyst
Required CredentialsBachelor's or higher in engineering, computer science, or related fields; experience with simulation softwareBachelor's or higher in statistics, mathematics, or related fields; proficiency in data analysis tools
Work EnvironmentEngineering teams, simulation labs, software development settingsBusiness, finance, healthcare, or tech companies analyzing data sets
Industry UsageManufacturing, aerospace, automotive, defenseFinance, marketing, healthcare, technology
Common Search/ComparisonYesYes

The Remote Modeling Simulation Engineer focuses on creating and running simulations to predict system behaviors, often in engineering or manufacturing contexts. In contrast, the Remote Data Analyst interprets data to inform business decisions across various industries. While both roles require analytical skills and technical knowledge, their tools, applications, and industry focus differ significantly.

What are the most commonly searched types of Modeling Simulation Engineer jobs in Boston, MA? The most popular types of Modeling Simulation Engineer jobs in Boston, MA are:
What are popular job titles related to Remote Modeling Simulation Engineer jobs in Boston, MA? For Remote Modeling Simulation Engineer jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Remote Modeling Simulation Engineer jobs in Boston, MA look for? The top searched job categories for Remote Modeling Simulation Engineer jobs in Boston, MA are:
What cities near Boston, MA are hiring for Remote Modeling Simulation Engineer jobs? Cities near Boston, MA with the most Remote Modeling Simulation Engineer job openings:

HEOR Modeling Director (Remote-Eligible)

Vrtx

Boston, MA • On-site, Remote

$204K - $306K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 7 days ago


Job description

Job Description

Job Summary:

Vertex is seeking a talented and motivated individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. The role is as a Director within the Modeling Center of Excellence (CoE), a designated group within the HEOR team that provides strategic and technical modeling support to HEOR, Market Access & Pricing, and the broader commercial organization. The main responsibility of the Director will be to lead the team that supports the HEOR disease/asset teams in developing health economic models, including models that will provide the foundations for HTA submissions, as well as early models to inform evidence generation needs. The Director will set the direction for modeling strategy across one or more therapeutic areas or pipeline assets. The Director will provide input into global product value strategy and tactics as well as input to design and interpretation of post-hoc clinical trial analyses and evidence generation studies that relate to economic models. The role has flexibility to be in-person, hybrid, or remote.

Key Responsibilities:

  • Set the direction for modeling strategy across one or more therapeutic areas or pipeline assets

  • Provide leadership and support to the HEOR Modeling team as they develop and roll out economic models to support product value strategy

  • Lead the development of global cost-effectiveness and budget impact models, and associated materials. The work may involve both in-house "hands-on" development of models (de novo programming) as well as management and quality assurance and validation of work conducted by external vendors

  • Conduct model trainings and provide support to regional teams in local adaptation process and development of HTA submissions, as well as continued support during negotiations with reimbursement authorities

  • Provide thought leadership on economic modeling to support development of strategic plans and evidence generation activities

  • Provide input into design and interpretation of evidence generation studies needed to support economic models

  • Provide subject matter expertise/knowledge to cross-functional partners to support understanding and appropriate application of relevant HEOR evidence in support of access/reimbursement

  • Present research findings at scientific congresses, participate in development of high-quality publications for peer-review

Minimum Qualifications:

  • Advanced degree in health economics or a related discipline (such as mathematics, statistics, economics, epidemiology)

  • Typically requires 10 years of relevant experience in health economics and outcomes research, or the equivalent combination of education and experience

  • Preference for previous supervisory/management experience

  • Extensive experience designing and developing health economic models; preferred experience in modeling work to support HTA submissions and negotiations

  • Excellent communication skills, strong oral/written presentation skills

  • Ability to manage complexity and ambiguity in a highly matrixed work environment

  • Ability to navigate and be successful in a fast-paced environment

Pay Range:

$204,000 - $306,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Remote-Eligible

Flex Eligibility Status:

In this Remote-Eligible role, you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Remote

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com