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Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Principal Scientist

Duties:Lead analytical method development, validation andtrouble-shootingfor drug substances and drug products and in-process testing for synthetic small molecules and/or synthetic peptide testing and characterization. Define analytical control strategies and implement methodologies fordevelopmentof late phase clinical programs. Collaborate closely with drug substance and drug product process development colleagues to achieve projectobjectives. Lead and mentor a group of analysts in supporting process development.Providecareer development guidance to the team members. Provideconcisesummary to cross-functional leadership for endorsement of key decisions. Oversee activities at contract manufacturing and testing sites. Author technical reports and analytical Chemistry, Manufacturing and Controls (CMC) sections in regulatory documents. Address analytical and product quality inquiries from health authorities. Supervises direct reports.

Requirements:PHD degree or (foreign equivalent) in analytical chemistry, chemistry, or related field & 3 years of experience in the job offered or in a process development-related occupation. Position requires 3 years of experience in the following:

1. Mass spectrometry knowledge inmechanismof different ionization techniques, configuration of mass spectrometry platforms by different vendors including Waters,ThermoFisher, or Agilent, and gas-phase ion chemistry for structuralelucidation;

2. Sample preparation including liquid-liquid extraction and solid phase microextraction for qualitative and quantitative analysis of both small molecules and largemolecules;

3. Analytical techniques including FT-IR (Fourier-transform infrared spectroscopy), NMR (nuclear magnetic resonance), and UV (ultraviolet-visible spectroscopy);

4. Chromatography and related separation techniques including RP-HPLC (reversed phase high-performance liquid chromatography) and GC (gas chromatography);

5. High-throughput analysis in processing multidimensional mass spectrometry-based data and implementing statistical analysis and interpreting statistical results; and

6. Software applications includingChemDraw,Xcalibur, orChemStationand programming language for data processing including Python orMatlab..

Contact:Interested candidatesplease apply viahttps://careers.amgen.com/en/search-jobsandsearch for job#R-243910

Job type:Full Time position. The annual salary for this position in the U.S. is$148,363.00- $171,657.00per year. Also, this position offers stock, retirement, medical, life and disability insurance and eligibility for an annual bonus or for sales roles, otherincentive compensation. For more detailsvisithttps://careers.amgen.com/life-at-amgen/benefits/

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.