ZipRecruiter

Log In

2

Remote Downstream Process Development Scientist Jobs in San Jose, CA

Nokia

Staff PIC Process Engineer

Sunnyvale, CA · On-site +1

As a Staff PIC Process Development Engineer , you will be a senior individual contributor within ... Proven ability to work effectively with remote fabs and crosssite teams Preferred Qualifications

Formfactor

Research & Development Intern

Livermore, CA · On-site +1

$37.15 - $48.77/hr

Contribute to earlystage process development and improvement efforts. * Collaborate with other ... Candidates with a bachelor's degree or master's degree in engineering, physics, materials science ...

Apex Systems

Data Scientist 1

Fremont, CA · On-site +1

Have a remote spot that can fall in the scientist or analyst realm with heavy work in Microsoft ... process discipline. * Experience analyzing, filtering, and preparing data for downstream use.

next page

Showing results 1-20

People also search for

All JobsRemote Downstream Process Development Scientist JobsRemote Downstream Process Development Scientist Jobs in San Jose, CA

Remote Downstream Process Development Scientist information

See San Jose, CA salary details

$24

$45

$72

How much do remote downstream process development scientist jobs pay per hour?

As of May 28, 2026, the average hourly pay for remote downstream process development scientist in San Jose, CA is $45.31, according to ZipRecruiter salary data. Most workers in this role earn between $33.22 and $54.09 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Remote Downstream Process Development Scientist, and why are they important?

To thrive as a Remote Downstream Process Development Scientist, you need a strong background in biochemistry, chemical engineering, or a related field, often supported by an advanced degree and experience in bioprocessing. Familiarity with chromatography systems, filtration technologies, and data analysis software, as well as knowledge of regulatory standards like GMP, is typically required. Exceptional problem-solving, project management, and cross-functional communication skills are crucial for remote collaboration and effective process optimization. These competencies ensure the efficient development, scale-up, and transfer of purification processes critical to biopharmaceutical manufacturing success.

How does a Remote Downstream Process Development Scientist typically collaborate with onsite laboratory teams?

As a Remote Downstream Process Development Scientist, collaboration with onsite laboratory teams is essential to ensure the smooth transfer of process knowledge, data interpretation, and troubleshooting. Communication is often facilitated through regular video meetings, shared digital lab notebooks, and project management tools. While you may not be physically present for hands-on experiments, you play a crucial role in designing studies, analyzing results, and providing guidance on process optimization. Building strong virtual relationships and maintaining clear, timely communication are key to overcoming challenges related to distance and ensuring project success.

What is a Remote Downstream Process Development Scientist?

A Remote Downstream Process Development Scientist is a professional who designs, optimizes, and scales processes for purifying and isolating biological products, such as proteins or antibodies, often in the biotechnology or pharmaceutical industries. They work remotely, leveraging digital tools to collaborate with teams, analyze data, and guide laboratory operations. Their responsibilities include developing protocols, troubleshooting purification steps, and ensuring that processes meet quality and regulatory standards. This role is critical for transforming lab-scale discoveries into commercially viable products.

What is the difference between Remote Downstream Process Development Scientist vs Remote Upstream Process Development Scientist?

AspectRemote Downstream Process Development ScientistRemote Upstream Process Development Scientist
Required CredentialsBachelor's or Master's in Biochemistry, Chemical Engineering, or related field; experience in chromatography and purification techniquesBachelor's or Master's in Biochemistry, Chemical Engineering, or related field; experience in cell culture and bioreactor operations
Work EnvironmentLaboratory and pilot plant settings, often collaborative teamsLaboratory and bioreactor environments, often collaborative teams
Industry UsagePharmaceutical and biotech companies focusing on drug purificationPharmaceutical and biotech companies focusing on bioprocessing

The main difference between a Remote Downstream Process Development Scientist and a Remote Upstream Process Development Scientist lies in their focus areas. Downstream scientists specialize in purification and separation techniques, while upstream scientists focus on cell culture and bioreactor processes. Both roles require similar educational backgrounds and are vital in biopharmaceutical development, but they target different stages of the production process.

What are the most commonly searched types of Downstream Process Development Scientist jobs in San Jose, CA? The most popular types of Downstream Process Development Scientist jobs in San Jose, CA are:
What are popular job titles related to Remote Downstream Process Development Scientist jobs in San Jose, CA? For Remote Downstream Process Development Scientist jobs in San Jose, CA, the most frequently searched job titles are:
What job categories do people searching Remote Downstream Process Development Scientist jobs in San Jose, CA look for? The top searched job categories for Remote Downstream Process Development Scientist jobs in San Jose, CA are:
What cities near San Jose, CA are hiring for Remote Downstream Process Development Scientist jobs? Cities near San Jose, CA with the most Remote Downstream Process Development Scientist job openings:
Remote Downstream Process Development Scientist jobs near you
Infographic showing various Remote Downstream Process Development Scientist job openings in San Jose, CA as of May 2026, with employment types broken down into 81% Full Time, 10% Part Time, and 9% Contract. Highlights an 3% In-person, and 97% Remote job distribution, with an average salary of $94,251 per year, or $45.3 per hour.

Head of Chemistry, Manufacturing & Controls (CMC)

Braveheart Bio

San Francisco, CA • On-site, Remote

Full-time

Posted 26 days ago

Job description

About us:
Braveheart Bio is a Bay Area-based biopharmaceutical company pioneering best-in-class therapies for cardiovascular disease. Our lead program is a next-generation myosin inhibitor, licensed from Hengrui Pharma, being developed to transform the treatment of hypertrophic cardiomyopathy (HCM)-the most common inherited cardiac disease.
Currently in Phase 3 clinical development in China for the more common obstructive form of HCM, our candidate has demonstrated a compelling clinical profile that may position it as a best-in-class therapy with meaningful differentiation.
With a proven leadership team, a strong financial foundation, and a high-value late-stage asset, Braveheart Bio represents an outstanding opportunity for ambitious, mission-driven professionals to make a tangible impact in a high-profile and rapidly evolving therapeutic area.
The role:
As Braveheart Bio advances its lead small molecule program toward late-stage development, the Head of CMC will serve as a key technical and operational leader, responsible for all Chemistry, Manufacturing, and Controls (CMC) activities across development and supply.
Reporting to the executive team, this individual will lead drug substance and drug product process development, manufacturing strategy, and external supply chain execution, while partnering closely with internal cross-functional teams and a network of global CDMOs and CROs. The Head of CMC will play a critical role in ensuring regulatory readiness, technical excellence, and scalable, compliant manufacturing to support clinical development and eventual commercialization. A central focus of the role will be driving commercial readiness and supporting a successful global launch, including process validation, scale-up to commercial volumes, qualification of a robust commercial supply network, and delivery of the launch CMC package to support NDA/MAA approval and market entry.
Key responsibilities:
  • Direct all aspects (DS/DP) of process development and supply chain operational activities for the company's programs; work closely with external CROs/CDMOs, collaborators, and/or partners to rapidly advance programs to key decision points.
  • Develop and direct strategies for upstream and downstream process development, analytical development, and formulation development (including management of associated external CDMOs/CROs).
  • Author and review technical sections for company's global regulatory submissions (INDs, CTAs, IMPDs, NDAs, MAAs, meeting requests, briefing documents, responses to health authority questions, etc.) related to assigned programs.
  • Collaborate with team members to efficiently evaluate, select, and manage contract service providers (CDMOs and CROs), including technology transfer, process scale-up, design of validation strategies, packaging development, and technical expertise with regards to routine/non-routine development and cGMP activities (e.g., deviations/investigations, process improvements, change controls, CAPAs, etc.).
  • Lead end-to-end commercial CMC readiness, including process performance qualification (PPQ), process validation, analytical method validation, and stability programs required to support NDA/MAA filings and global launch.
  • Build and qualify the commercial supply network, including launch and post-launch demand planning, inspection readiness for pre-approval inspections (PAI), serialization and packaging strategy, and partnership with Commercial, Quality, and Regulatory to ensure on-time product availability across launch markets.
  • Oversee the development and maintenance of the budget for assigned program activities, including the preparation of cost estimates for new work.
  • Develop and/or provide technical review of development documents (batch records, experimental data, protocols, reports, analytical methods, SOPs, etc.).
  • Play a leadership role in the creation, maintenance, improvement, and compliance with quality system.
  • Contribute to the generation and protection of company intellectual property.
  • Lead, develop, and mentor direct reports.
  • Demonstrate success in a dynamic, interactive, fast-paced, and entrepreneurial environment.

Required experience & skills:
  • Ph.D. (or equivalent) in Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or a closely related field; exceptionally strong master's candidates will be considered
  • Fifteen-plus years' experience in the pharmaceutical or biotech industry, with five-plus years' demonstrated leadership in small molecule process development
  • Experience with global pharmaceutical/biotech development and manufacturing operations for development-stage small molecule assets, including upstream/downstream process development, formulation development, analytical development, and device development
  • Leadership experience in managing diverse project activities with contract CDMO facilities
  • Direct experience with successful registrations and commercial launch of novel assets
  • Hands-on experience leading commercial readiness activities, including PPQ, process and analytical method validation, pre-approval inspection (PAI) readiness, and qualification of commercial-scale supply for global launch
  • Experience with clinical supply management, process scale-up and technology transfer, cGMPs, and ICH guidelines, as well as the CMC content of global regulatory submissions
  • Experience with small molecule development programs, from early stage through commercial
  • Knowledge of cGMP regulations
  • Hands-on, roll-up-your-sleeves approach, with high sense of urgency and drive for results
  • Demonstrated communication, problem-solving, and negotiation/decision-making skills
  • Ability to think outside of the box and challenge the status quo
  • Natural entrepreneurial spirit with unrelenting dedication to delivering results
  • Desire to work in a fast-paced, innovative environment
  • Natural collaborator who enjoys working on a cross-functional team
  • Ability to travel 10-20%, domestic and/or international

Base Salary Range: $300K - $375K
Braveheart participates in the federal E-Verify program to confirm employment authorization for all new hires. To learn more about E-Verify please review this poster.
We are an equal opportunity employer.
We are committed to inclusion and diversity, and we do not discriminate on the basis of race, gender, religion, gender, sexual orientation, age, color, marital status, veteran status, disability status, national origin, or any characteristic protected under applicable law.
Braveheart participates in the federal E-Verify program to confirm employment authorization for all new hires. To learn more about E-Verify please review this poster.

Apply