Remote Downstream Process Development Scientist Jobs in California

Labcorp is a global leader in laboratory services, providing the insights and answers that help healthcare providers, patients, researchers, pharmaceutical companies and health systems make confident decisions and improve outcomes. Through our unparalleled science, data, technology and laboratory network, we advance diagnostics, accelerate innovation and help address some of the world's most important health challenges. As we shape the future of healthcare, we are leveraging advanced technologies, intelligent digital solutions and data-driven innovation across our operations to enhance how work gets done and deliver greater value to customers and patients. With our global scale and deep expertise, you'll have the opportunity to do meaningful work, grow your career and make a real impact on people's health around the world. Together, we're improving health and improving lives.

Labcorp is seeking a US based remote Lead Bioinformatics Scientist to join our team!

Job Responsibilities:

The SampletoAnswer Center of Excellence (CoE) within the LabCorp Information Technology department manages a wide range of diagnostic tests using advanced technologies such as nextgeneration sequencing and microarrays. This position provides a unique opportunity to interact with CoE personnel and gain handson experience solving realworld problems in data science and bioinformatics. The role also contributes directly to LabCorp's research and development efforts by addressing complex data science challenges and accelerating critical production development initiatives.

Produce innovative solutions driven by exploratory data analysis from complex and high-dimensional datasets. Apply knowledge of statistics, data modeling, data sciences and artificial intelligence to recognize patterns, identify opportunities and make valuable discoveries. Use a flexible, analytical approach to design, develop, and evaluate predictive models for single-gene non-invasive Fetal Screening (NIFS). Generate and test hypotheses and be involved from ideation through delivery.

Key Responsibilities

• Collaborates with R&D scientists on the development of new assays, measurement technologies, and tests for evaluating clinical conditions.

• Perform sophisticated analysis of genomic, transcriptomic, or proteomic datasets using state-of-the-art bioinformatics tools and NGS pipelines.

• Performs statistical and bioinformatics analyses of experimental data produced by clinical testing instruments such as DNA sequencers and other molecular instruments.

• Conducts data mining over internally produced and publicly available data sets.

• Provides analysis information to management to aid in decision making on the development of new laboratory developed tests.

• Develop statistical classifiers and decision trees integrating spanning read support, flanking-read ratios, allele dropout indicators, and confidence intervals.

• Apply a wide range of bioinformatics algorithms and develop novel computational approaches.

• Investigate assay limitations at the molecular level and define boundaries of clinical reporting.

• Develop and optimize complex analysis pipelines based on deep knowledge of bioinformatics algorithms.

• Architect production-grade Nextflow pipelines for whole-genome sequencing, including caller selection, annotation strategy (AnnotSV, Nirvana), and QC threshold design.

• Lead bioinformatics proof-of-concept for sequencer transitions, including concordance analysis, metric comparison, GIAB benchmarking, and cost-benefit recommendations.

• Drive improvements in accuracy, cost of goods sold (COGS), and turnaround time across the pipeline portfolio.

• Establish quality control metrics and procedures to ensure data integrity across production pipelines.

• Guide result interpretation and reporting standards in collaboration with clinical and commercial stakeholders.

• Set QC thresholds for new sample metrics and make production-impacting recommendations.

Minimum Qualifications

• Ph.D. in bioinformatics, computational biology, genetics, or computer science.

• 3 or more years of experience in biotechnology

• 5 or more years of experience in programming languages in bioinformatics, such as Python, R, Perl, or Java.

Preferred Qualifications

• 5 or more years of experience with high-throughput sequencing data and bioinformatics tools like BLAST, GATK, or Bowtie.

• 5 or more years of experience with Linux/Unix environments and high-performance computing (HPC) or cloud platforms.

Additional Job Standards

• Ability to effectively provide guidance to junior team members, sharing your expertise and contributing to a collaborative learning environment.

• Ability to demonstrate success in technical proficiency, scientific creativity, collaboration with others and independent thought.

• Ability to provide evidence of relevant research expertise in the form of presentations, software, technical publications, and knowledge of applications.

• Ability to demonstrate proficiency in data analysis and statistical learning.

• Ability to exercise independent judgment in developing methods, techniques and evaluation criteria for obtaining results.

Application window open through: 08/27/2026

Pay Range: $120k - $150k (USD)

All job offers will bebased on a candidate's skills and prior relevant experience, applicabledegrees/certifications,as well as internal equity and market data. The position is also eligible for an annual bonus under the Labcorp Bonus Plan.Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.

Labcorp is a global leader in diagnostic testing and drug development solutions, helping healthcare providers, researchers, and patients make informed decisions that advance care. We are dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. We are leading the transformation of the genetics industry, by making clinical-grade genetic information affordable and accessible to guide health decisions across all stages of life.Join us in our mission to improve health and improve lives.

Benefits:Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan.Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan.Employees who are regularly scheduled toworka 7 on/7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO. For more detailed information, pleaseclick here.

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.

We encourage all to apply

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