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Remote Director Clinical Data Management Jobs (NOW HIRING)

Sumitomo Pharma

Clinical Data Manager

$130K - $163K/yr

This position reports to the Executive Director, Clinical Data Management, Oncology and is part of ... Primarily remote role with periodic on-site meetings in office. Must be able to travel domestically ...

Faeth Therapeutics

Clinical Data Manager

Austin, TX · Remote

$125K - $175K/yr

We are a small, focused team where every person has direct impact -- united by a shared commitment ... Remote (U.S.) Responsibilities: * Lead day-to-day data management activities for assigned clinical ...

Faeth Therapeutics

Clinical Data Manager

Austin, TX · Remote

$125K - $175K/yr

We are a small, focused team where every person has direct impact - united by a shared commitment ... Remote (U.S.) Responsibilities: * Lead day-to-day data management activities for assigned clinical ...

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Remote Director Clinical Data Management information

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$51.5K

$100.1K

$167K

How much do remote director clinical data management jobs pay per year?

As of Jul 27, 2026, the average yearly pay for remote director clinical data management in the United States is $100,124.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,000.00 and $109,000.00 per year, depending on experience, location, and employer.

What is the difference between Remote Director Clinical Data Management vs Remote Clinical Data Manager?

AspectRemote Director Clinical Data ManagementRemote Clinical Data Manager
ResponsibilitiesOversees entire clinical data management operations, strategic planning, team leadershipHandles data collection, entry, validation, and reporting tasks
Required CredentialsBachelor's/Master's in life sciences, extensive experience, leadership skillsBachelor's in life sciences, experience in data management, technical skills
Work EnvironmentSenior management, cross-functional teams, strategic meetingsData entry teams, clinical sites, data analysis tasks

The main difference lies in scope and seniority. The Remote Director Clinical Data Management focuses on strategic oversight and leadership, while the Remote Clinical Data Manager handles day-to-day data tasks. Both roles require relevant credentials and industry experience, but the director position involves higher-level decision-making and team management.

More about Remote Director Clinical Data Management jobs
What cities are hiring for Remote Director Clinical Data Management jobs? Cities with the most Remote Director Clinical Data Management job openings:
What states have the most Remote Director Clinical Data Management jobs? States with the most job openings for Remote Director Clinical Data Management jobs include:
What job categories do people searching Remote Director Clinical Data Management jobs look for? The top searched job categories for Remote Director Clinical Data Management jobs are:
Remote Director Clinical Data Management jobs near you
Infographic showing various Remote Director Clinical Data Management job openings in the United States as of July 2026, with employment types broken down into 2% As Needed, 73% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $100,124 per year, or $48.1 per hour.
Senior Director, Clinical Data Management

Senior Director, Clinical Data Management

Amylyx Pharmaceuticals

Cambridge, MA • Remote

Other

Posted 2 days ago

Job description

The Opportunity

Amylyx Pharmaceuticals is seeking a strategic and experienced Senior Director, Clinical Data Management to lead the evolution of our Clinical Data Management function during a critical stage of company growth. This role will define and execute the long-term vision for data management across the clinical development portfolio, ensuring the delivery of high-quality data to support regulatory submissions and key business decisions.

The Senior Director will build and scale internal capabilities while transitioning from a predominantly outsourced model, establishing the systems, processes, and organizational infrastructure necessary to support late-stage development programs and future commercial operations. This individual will serve as a key leader within the Biometrics organization and collaborate closely with cross-functional stakeholders to drive operational excellence and innovation in data management.

Responsibilities

  • Establish and execute the Clinical Data Management strategy aligned with Amylyx's development and growth objectives
  • Build and scale an internal Clinical Data Management organization and the operational roadmap for bringing selected Data Management activities in-house while maintaining effective oversight of CRO partnerships
  • Provide leadership and accountability for all Clinical Data Management activities across Amylyx-sponsored clinical trials
  • Ensure high-quality data collection, integration, and delivery to support regulatory submissions and business decision-making
  • Oversee end-to-end data management deliverables, including study start-up, database design, edit check strategy, reconciliation, database lock, and submission readiness
  • Lead the evaluation and implementation of data management technologies, systems, and process improvements
  • Develop and manage vendor and CRO relationships, including governance, performance metrics, and quality oversight
  • Establish and maintain departmental SOPs, work instructions, governance structures, and operating models
  • Ensure compliance with GCP, ICH, and applicable regulatory standards, and lead inspection readiness activities

Required Qualifications

  • 12-15 years and BA/BS, 10-12 years and MA/MS, or 5+ years and PhD
  • 6+ years of leadership experience managing Clinical Data Management teams and functions
  • Demonstrated success supporting Phase 2 and Phase 3 clinical programs
  • Experience building, scaling, or transforming Clinical Data Management organizations
  • Strong knowledge of EDC systems, clinical data standards, medical coding, and data reconciliation processes
  • Experience supporting major regulatory submissions, such as NDA, BLA, or MAA
  • Proven ability to influence cross-functional stakeholders and senior leadership

Preferred Requirements

  • Experience transitioning data management activities from outsourced to in-house models
  • Familiarity with risk-based methodologies, automation, and advanced data management technologies
  • Track record of driving process optimization and operational excellence initiatives

Work Location and Conditions

  • At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii Michigan and Tennessee. 
    You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
    You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

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