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Remote Clinical Operations Analyst Jobs in Colorado

Partner with Analytics and Finance to define and monitor clinical KPIs tied to value-based ... Fully-remote work environment available * Full benefits package * A collaborative and transparent ...

The Clinical & Endpoint Research Associate supports site operations with a primary focus on ... Remote candidates are welcome to apply. In this position you will: * Contact study sites and ...

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Remote Clinical Operations Analyst information

What is the difference between Remote Clinical Operations Analyst vs Remote Clinical Research Coordinator?

AspectRemote Clinical Operations AnalystRemote Clinical Research Coordinator
Required CredentialsBachelor's in life sciences, clinical research experience, knowledge of regulationsBachelor's in health sciences, clinical research experience, familiarity with protocols
Work EnvironmentData analysis, project management, cross-functional teamsParticipant coordination, site management, protocol adherence
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsResearch sites, hospitals, academic institutions

The Remote Clinical Operations Analyst primarily focuses on data analysis, project management, and supporting clinical trial operations remotely. In contrast, the Remote Clinical Research Coordinator handles participant recruitment, site coordination, and protocol compliance. Both roles require clinical research knowledge and often overlap in industry usage, but they differ in daily responsibilities and focus areas.

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Infographic showing various Remote Clinical Operations Analyst job openings in Colorado as of July 2026, with employment types broken down into 1% Locum Tenens, 1% Internship, 83% Full Time, 9% Part Time, 1% Temporary, and 5% Contract. Highlights an 81% Physical, 6% Hybrid, and 13% Remote job distribution.
Director, Clinical Operations

Director, Clinical Operations

Karoo Health

Denver, CO • On-site, Remote

Full-time

Re-posted 13 days ago


Job description

An Industry Defining Company
Karoo is a venture-backed startup on a mission to transform cardiovascular care. Our platform is designed to empower large provider groups and health systems to succeed in value-based care contracts with payers by improving patient outcomes and reducing cost of care through better coordination, analytics, and disease management. We are currently live in multiple VBC contracts across more than ten states with significant growth plans for 2026 and beyond. While our initial focus is cardiology, we are building a scalable operating system for managing complex conditions across the healthcare spectrum.
This is a rare opportunity to join a mission-driven founding team at a pivotal stage and help define the future of healthcare technology, with the power to improve the lives of patients with cardiovascular disease, the number one cause of death in America today.
The Role
The Director of Clinical Operations will lead the development, refinement, and execution of Karoo's clinical care model. This leader will translate clinical strategy into scalable workflows, protocols, staffing models, and operational playbooks to ensure high-quality, compliant, and efficient care delivery across markets.
This role is ideal for a clinically trained operator with cardiology experience who understands value-based care and thrives in early-stage environments where building and iterating are core to the job.
This role will directly shape how care is delivered at Karoo, from the patient experience to clinical outcomes to financial performance under value-based contracts.
What You'll Do
Clinical Model Implementation & Iteration
  • Own the implementation and ongoing refinement of Karoo Health care model, including risk stratification, and condition based care protocol development.
  • Translate evidence-based cardiology guidelines into practical and scalable care protocols.
  • Test, iterate, and standardize care protocols to meet the needs of individual markets and payer arrangements.
  • Ensure the Karoo Health care model supports value-based care (full upside and downside risk) through alignment of patient, provider, and payer specific outcomes.

Clinical Operations Execution
  • Operationalize the clinical model across care teams, developing SOPs, staffing models, role definitions, and training materials.
  • Identify operational bottlenecks or clinical variation and drive continuous improvement initiatives.
  • Support market launches by ensuring clinical readiness, workflows, and staffing are in place.

Care Team Leadership
  • Provide operational support to Karoo's clinical team (RNs, LCSW, MAs, etc.)
  • Support hiring, onboarding, training, and performance management of clinical staff.
  • Foster a culture of patient-centered, data-informed, high-quality care delivery.

Value-Based Care & Performance Management
  • Partner with Analytics and Finance to define and monitor clinical KPIs tied to value-based contracts (e.g., patient engagement, clinical outcomes, utilization, and financial outcomes).
  • Use data to assess clinical effectiveness and identify opportunities to improve outcomes and reduce avoidable utilization.
  • Support shared savings performance by aligning clinical workflows with payer and provider incentives.

Provider Partnership Enablement
  • Collaborate with partner cardiology practices to ensure smooth integration of Karoo's clinical model into existing workflows.
  • Serve as a key operational liaison to practice leaders, addressing day-to-day clinical process questions and improvement opportunities.
  • Support provider onboarding, clinical training, and ongoing adoption of Karoo protocols.

Quality, Safety & Compliance
  • Ensure clinical operations meet regulatory, licensure, and quality standards across states and care settings.
  • Partner with the CMO and clinical leaders on quality oversight, incident review, and continuous quality improvement efforts.
  • Maintain up-to-date clinical policies and documentation standards.

Cross-Functional Collaboration
  • Work closely with Product to inform clinical requirements for tools, workflows, and dashboards.
  • Partner with Market Ops, and Growth teams to align clinical delivery with expansion goals.
  • Provide clinical-operations input into payer discussions and new market planning.

What We're Looking For
  • Clinical background in cardiology. NP, PA, or MD degree is considered a strong plus.
  • 5+ years operational and people management experience.
  • Experience in value-based care provider organizations. Experience with participation in full upside and downside risk arrangements is a plus.
  • Experience building or scaling clinical programs in a startup or established health system.
  • Experience in a value-based provider startup organization is a plus.
  • Strong systems thinker who can translate clinical strategy into operational reality.
  • Comfortable operating in ambiguity and iterating quickly as the organization grows.
  • Collaborative, pragmatic leader with excellent communication skills.

Why Join Us
  • Competitive salary and equity
  • Fully-remote work environment available
  • Full benefits package
  • A collaborative and transparent company culture that values creativity and ownership