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Remote Ai Prompt Engineer Jobs in Minnesota (NOW HIRING)

Senior AI-ML Engineer

Rochester, MN · On-site +1

$106K - $145K/yr

AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer ... This position is a combination of remote and on-site work; individual must live within a 100 mile ...

Senior AI-ML Engineer

Rochester, MN · On-site +1

$106K - $145K/yr

AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer ... This position is a combination of remote and on-site work; individual must live within a 100 mile ...

Senior Data Engineer

Eden Prairie, MN · Remote

$108K - $146K/yr

Knowledge on building Generative AI/LLM solutions, including RAG pipelines, prompt engineering, and integration with enterprise data platforms *All Telecommuters will be required to adhere to ...

Showing results 41-60

Remote Ai Prompt Engineer information

What is a remote AI prompt engineer?

A Remote AI Prompt Engineer designs, refines, and optimizes prompts to improve AI-generated responses in various applications, such as chatbots, content generation, and automation tools. They work remotely to test AI models, analyze outputs, and develop strategies to enhance AI performance. This role requires strong language skills, creativity, and an understanding of AI model behavior. Their work helps ensure AI systems generate accurate, relevant, and high-quality responses.

What does a remote AI prompt engineer do?

A typical day for a Remote AI Prompt Engineer involves designing, testing, and refining prompts for various AI models to improve their outputs based on project goals. You may collaborate with product managers, data scientists, and software engineers through digital communication tools to align prompt strategies with business needs. Reviewing model responses, analyzing results, and documenting prompt performance are regular tasks. Additionally, you may participate in virtual team meetings and training sessions to stay updated on new AI developments. This role offers a diverse mix of technical problem-solving and creative experimentation within a flexible remote work environment.

What are the key skills and qualifications needed to thrive in the remote AI prompt engineer position, and why are they important?

To thrive as a Remote AI Prompt Engineer, you should have a strong grasp of natural language processing, prompt engineering techniques, and a background in computer science or related fields. Familiarity with AI platforms (such as OpenAI's GPT or similar LLMs), version control systems, and experience with relevant programming languages like Python are highly valuable, and certifications in AI or machine learning are a plus. Exceptional analytical thinking, clear written communication, creativity, and the ability to work independently are key soft skills for this role. These capabilities enable prompt engineers to develop effective prompts, collaborate remotely, and drive high-quality AI-driven outcomes.

What are the most commonly searched types of Ai Prompt Engineer jobs in Minnesota?

The most popular types of Ai Prompt Engineer jobs in Minnesota are:

What are popular job titles related to Remote Ai Prompt Engineer jobs in Minnesota?

For Remote Ai Prompt Engineer jobs in Minnesota, the most frequently searched job titles are:

What job categories do people searching Remote Ai Prompt Engineer jobs in Minnesota look for?

The top searched job categories for Remote Ai Prompt Engineer jobs in Minnesota are:

What cities in Minnesota are hiring for Remote Ai Prompt Engineer jobs?

Cities in Minnesota with the most Remote Ai Prompt Engineer job openings:

Infographic showing various Remote Ai Prompt Engineer job openings in Minnesota as of August 2026, with employment types broken down into 4% Internship, 70% Full Time, 12% Part Time, and 14% Contract. Highlights an 100% Remote job distribution.

Senior AI-ML Engineer

Mayo Clinic

Rochester, MN • On-site, Remote

$106K - $145K/yr

Full-time

Medical, Dental, Vision, Retirement

Posted 9 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 699 frontline employees who took The Breakroom Quiz

127th of 889 rated healthcare providers


Job description

AI/ML Engineers at Mayo Clinic play a pivotal role in the union of data, systems, and computer sciences. They work closely with a multidisciplinary team, including clinicians, user experience designers, product managers, IT professionals, and external partners, to develop and deploy effective, efficient, and ethical AI/ML solutions into clinical practice to enhance patient care and operational efficiency.
 

As a Senior AI/ML Engineer, you may work on the full spectrum of the AI life cycle from ideation to production. You understand the clinical environment well, including workflows, challenges, and requirements of healthcare providers and patients. You will leverage advanced techniques in AI/ML to analyze vast amounts of healthcare data, including patient records, medical imaging, and genomic information, to develop AI solutions that meet clinical needs and are integrated smoothly into clinical processes. You will develop, integrate, and standardize software components and create, maintain, and follow quality system procedures. You will guide the engineering of systems that are pivotal to developing and deploying these solutions, which encompass everything from design requirements, development, component creation, verification, non-clinical validation, and risk mitigation to ensure our digital health technology products meet and exceed regulatory requirements and setting new benchmarks for safety and effectiveness in clinical settings. Your expertise will also extend to facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines. 
This role is instrumental in providing consultative services to departments and divisions, offering insights into complex business problems. Your ability to communicate complex findings in easily understandable terms to non-technical users will bridge the gap between sophisticated AI technologies and clinical applications.

   Leading component design, development, integration, and standardization to create AI-driven solutions that seamlessly integrate into clinical practice to enhance patient care and clinic operations.
   Collaborating with a multidisciplinary team, including clinicians, user experience designers, product managers, and IT professionals, to understand user needs, workflows, and clinical requirements and assess feasibility. Translating user feedback and requirements into design concepts and usability specifications for AI solutions.
   Leveraging machine learning techniques such as deep learning, natural language processing, computer vision, large language models, etc., to lead the design, development, and deployment of end-to-end AI solutions for healthcare applications.
   Establishing evaluation methodologies and performance metrics to assess AI solutions' effectiveness, usability, and impact in real-world healthcare settings.
   Explaining data analysis results to guide strategic choices and clarify complex insights for non-technical users to connect AI technologies and clinical applications. 
   Overseeing the engineering of systems crucial for developing and deploying AI solutions.
   Facilitating consistent and automated AI software solution development and releases through the design, testing, and maintenance of tools and associated CI/CD pipelines.
   Contributing to implementing the best practices and standards for AI development and deployment methodologies, tools, and platforms.
   Providing mentorship, guidance, and technical leadership to junior engineers within the AI enablement team. 
   Providing consultative services on areas of expertise to clinical work units or AI product teams, offering insights and strategies to address complex business problems.
   Providing training and education to healthcare staff on AI tools and technologies.
   Contributing to developing new AI methods and technologies that can advance the state-of-the-art in healthcare AI. 

This position is a combination of remote and on-site work; individual must live within a 100 mile driving distance to the Arizona, Jacksonville or Rochester Mayo Clinic campus.

**Visa sponsorship is not available for this position.  Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

  A master's degree in engineering, computer science, mathematics, health science, or a related field with 4 years of experience, a bachelor's degree with 6 years of experience. 
  Extensive experience applying AI and machine learning in production healthcare environments or similar highly regulated or technology focused industries, showcasing an understanding of healthcare technology.
  Demonstrated leadership in managing complex projects, with a proven ability to navigate intricate project requirements and deliver successful outcomes.
  Proficiency in fostering collaboration across diverse teams and effectively communicating complex technical concepts to non-technical stakeholders.
  Demonstrated expertise in cloud infrastructure environment and software development tools.
  Experience working with large, complex, and heterogeneous data sets, preferably in healthcare. 
  Skilled in AI/ML techniques and frameworks.
  Familiarity with best practices in data engineering, data science, AI Engineering, and the MLOps communities.
  Demonstrated initiative in administration, education, software development, and technical reporting. 
  A commitment to mentoring and training less-experienced team members, coupled with strong interpersonal, communication, and time management skills.


Preferred Qualifications: 
  A Ph.D. or other doctorate is preferred. 
  Strong expertise in AI/ML techniques and frameworks, such as deep learning, natural language processing, and Generative AI, with proficiency in tools like Python, TensorFlow, PyTorch, sci-kit-learn, Keras, etc.
  Knowledge of the healthcare domain, including clinical workflows, electronic health records, medical terminologies, regulatory requirements, and industry standards.
  Familiarity with systems or quality engineering best practices, regulatory standards, and compliance frameworks, with the ability to adapt these effectively to different project scenarios.
  Demonstrated experience leading technical/quantitative teams in a regulated environment.
  Demonstrated experience creating risk management files and verification/validation strategies for digital health technology products within the healthcare industry.
  Strong expertise in user-centered design, human factors engineering, usability testing methodologies, and evaluation across AI product development. Ability to conduct expert reviews using established usability practices and methods. Presents findings in easy-to-understand terms for the business or clinical practice.


What Mayo Clinic employees say

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919