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Python Jobs in St Louis, MO (NOW HIRING)

The Timberline Group

Openstack Developer

Saint Louis, MO · On-site

$125 - $150/hr

Strong development background in Python and GoLang Position's most critical responsibilities - * Strong development background on Python * Experience on Kubernetes or Dockers Desirable qualifications

Stellar IT Group

Data Analyst

Saint Louis, MO · On-site

We are seeking a Data Analyst with strong SQL and Python expertise to support data validation, data quality, and exploratory data analysis. This role focuses on ensuring data is accurate, reliable ...

GRVTY

Data Scientist, Expert

Arnold, MO · On-site

Maintain Legacy Python codebase, integrate codebase new security requirements and future Source dissemination solutions. * Collaborate with GEOINT content teams to integrate automated quality checks ...

GRVTY

Data Scientist, Mid

Arnold, MO · On-site

Maintain Legacy Python codebase, integrate codebase new security requirements and future Source dissemination solutions. * Collaborate with GEOINT content teams to integrate automated quality checks ...

Stellar IT Group

Data Scientist

Saint Louis, MO · On-site

Advanced SQL + Python (core requirement); Joins, CTEs, window functions, analytical queries * Hands-on with data quality, validation, and reconciliation * Strong in backend data modeling ...

GRVTY

Data Scientist, Expert

Arnold, MO · On-site

Maintain Legacy Python codebase, integrate codebase new security requirements and future Source dissemination solutions. * Collaborate with GEOINT content teams to integrate automated quality checks ...

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All JobsPython JobsPython Jobs in St. Louis, MO

Python information

See St Louis, MO salary details

$12

$56

$83

How much do python jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for python in St. Louis, MO is $56.99, according to ZipRecruiter salary data. Most workers in this role earn between $46.97 and $64.76 per hour, depending on experience, location, and employer.

What is Python?

Python is a programming language used to write or develop a variety of programs and applications. The software developer community uses Python for programming because it is a simple language that is easy to test and debug. Large internet companies such as Facebook, Google, Reddit, and Amazon use Python, and so do government agencies such as NASA. Programmer professionals have used Python to help build popular software such as Autodesk Maya and other visual design applications. Financial professionals and stock traders use Python when scripting algorithms for economic predictions or computerized trading.

What is a Python developer?

A Python developer is a software programmer who specializes in writing, testing, and maintaining code using the Python programming language. They can work on a variety of projects, including web development, data analysis, machine learning, automation, and scripting. Python developers often collaborate with other team members to design solutions and ensure the functionality and performance of applications. Their responsibilities may also include debugging programs, integrating third-party services, and writing documentation.

What are the key skills and qualifications needed to thrive as a Python developer?

To thrive as a Python Developer, you need strong programming skills in Python, knowledge of software development principles, and typically a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and experience with databases are highly valued, along with certifications like PCEP or PCAP. Effective problem-solving, communication, and teamwork are essential soft skills to excel in collaborative and dynamic environments. These skills collectively ensure the delivery of robust, maintainable code and efficient project outcomes in technology-driven organizations.

What are some common challenges Python developers face when working on large-scale projects?

Python developers often encounter challenges such as managing dependencies, ensuring code scalability, and maintaining performance on large-scale projects. Collaboration with cross-functional teams can add complexity, especially when integrating with systems written in other languages. Adopting best practices like modular code structure, thorough documentation, and automated testing can help mitigate these challenges and streamline teamwork.

What is the difference between Python developer vs Java developer?

AspectPython DeveloperJava Developer
Required CredentialsBachelor's in CS or related field, Python certifications (optional)Bachelor's in CS or related field, Java certifications (optional)
Work EnvironmentWeb development, data science, automationEnterprise applications, Android development, backend systems
Industry UsageTech startups, data analysis firms, automation companiesFinancial services, large enterprise software, mobile app companies

Python developers focus on scripting, data analysis, and web development, often working in startups or data-driven fields. Java developers typically work on large-scale enterprise applications and Android apps. While both roles require programming skills and similar educational backgrounds, their industry applications and project types differ significantly.

Can I get a job with just Python?

A Python developer role typically requires proficiency in Python programming, along with knowledge of related tools like frameworks, libraries, and version control. While Python skills are essential, employers often prefer candidates with experience in problem-solving, data structures, and sometimes additional skills such as databases or web development. Certifications or practical projects can also enhance job prospects, but having only Python may limit opportunities for more advanced or specialized positions.

Does Python have good job opportunities?

Python developers have strong job prospects across various industries such as technology, finance, and data science. Proficiency in frameworks like Django or Flask and knowledge of data analysis tools can enhance employability, with many roles requiring experience in version control and problem-solving skills.

What jobs can I do with Python?

Python is used in a variety of roles including software developer, data analyst, data scientist, machine learning engineer, web developer, automation engineer, and cybersecurity specialist. These jobs often require knowledge of frameworks, libraries, and tools like Django, Flask, Pandas, and TensorFlow, and may involve working in teams or on specific platforms. Python skills are valuable across industries such as technology, finance, healthcare, and research.

Which Python job is in demand?

Python developer roles are highly in demand across industries such as technology, finance, and data science. Skills in frameworks like Django or Flask, along with knowledge of data analysis tools like Pandas and NumPy, enhance job prospects. Certifications and experience with cloud platforms can also improve employability.
More about Python jobs

What are the most commonly searched types of Python jobs in St. Louis, MO?

The most popular types of Python jobs in St. Louis, MO are:

What are popular job titles related to Python jobs in St. Louis, MO?

For Python jobs in St. Louis, MO, the most frequently searched job titles are:

What job categories do people searching Python jobs in St. Louis, MO look for?

The top searched job categories for Python jobs in St. Louis, MO are:

What cities near St. Louis, MO are hiring for Python jobs?

Cities near St. Louis, MO with the most Python job openings:

Python jobs near you
Infographic showing various Python job openings in St. Louis, MO as of September 2026, with employment types broken down into 2% Internship, 86% Full Time, 7% Part Time, and 5% Contract. Highlights an 80% Physical, 4% Hybrid, and 16% Remote job distribution, with an average salary of $118,546 per year, or $57 per hour.

MSS Developers (Various Locations)

O Fallon, IL • On-site

Agile Defense
IT Services • 201 - 500 employees
Learn more about Agile Defenseexternal

$135K - $165K/yr

Full-time

Posted 5 days ago

Job description

About Agile Defense
 
At Agile Defense we know that action defines the outcome and new challenges require new solutions. That’s why we always look to the future and embrace change with an unmovable spirit and the courage to build for what comes next.
 
Our vision is to bring adaptive innovation to support our nation's most important missions through the seamless integration of advanced technologies, elite minds, and unparalleled agility—leveraging a foundation of speed, flexibility, and ingenuity to strengthen and protect our nation’s vital interests.

Job Title: MSS Developer
Location: On-Site, Various Locations (see below)
  • Peterson Space Force Base, CO
  • Stuttgart, Germany: Patch Barracks, Kelley Barracks
  • Falls Church, VA
  • Arlington, VA Pentagon
  • Ft. Meade, MD
  • Tampa, FL: MacDill AFB
  • Doral (Miami), FL: SOUTHCOM HQ
  • O'Fallon (St. Louis), IL: Scott AFB
  • Omaha, NE: Offutt AFB
  • Colorado Springs, CO: Peterson SFB
  • Honolulu, HI: Camp H.M. Smith
Clearance Level: This position requires candidates to be U.S. citizens and to possess, at minimum, an active Secret security clearance. Roles under this requisition may require higher-level clearances, including TS/SCI, which candidates must be able to obtain and maintain based on project assignment. 
Job Description
Build Mission-Critical Analytics and Applications 
  • Build and maintain operator-facing dashboards, applications, and decision surfaces aligned to J7 mission workflows
  • Create intuitive, self-service capabilities that empower operators to explore data independently
  • Build automated workflows that deliver timely insights to stakeholders across the directorate 
  • Ensure data accuracy and consistency across all MSS deliverables 
Drive Hands-On Platform Engineering 
  • Develop and maintain data pipelines, ontology, and access controls on MSS and the underlying Palantir stack
  • Integrate external data sources into a well-modeled data foundation
  • Ensure AI/AIP workflows have a well-modeled data foundation and that model outputs are surfaced in operationally useful ways
  • Partner with mission leaders to understand analytical needs and translate requirements into technical solutions 
Enable Data-Driven Decision Making 
  • Create compelling data visualizations that communicate complex insights to diverse audiences 
  • Build interactive tools that allow operators to drill down into data and explore different scenarios
  • Design alerting and monitoring systems that proactively identify mission opportunities and risks
  • Collaborate with teams to establish KPIs and success metrics that drive mission performance
Optimize Platform Performance 
  • Develop efficient data models and query optimization strategies for fast, reliable reporting Implement caching and aggregation strategies to ensure optimal dashboard and application performance 
  • Build scalable MSS solutions that can handle growing data volumes and user bases
  • Provide day-to-day operator support and escalate complex platform issues to senior engineers as appropriate
Foster Analytics Excellence 
  • Contribute reusable platform content, including ontology patterns, dashboard templates, and integration recipes, to support continuous curriculum refresh Document data sources, metrics definitions, and analytical methodologies for organizational knowledge
  • Support validation of the FDE&T model for potential extension to additional Combatant Commands, Service components, and functional commands
  • Stay current with MSS/Palantir technologies and advocate for new tools and approaches that improve mission analytics 
Required Skills
  • Bachelor's degree in computer science, engineering, or a quantitative discipline; extensive Palantir experience will substitute. 
  • 4+ years of software or data engineering experience (data analysis or data science experience considered), including 1.5+ years hands-on with Palantir Foundry, Gotham, AIP, or MSS
  • Demonstrated experience building dashboards, applications, or pipelines for operational end users 
  • Working proficiency in ontology design, pipeline authoring using PySpark, Code Repositories, or Pipeline Builder 
  • Active US government security clearance
Preferred Skills
  • Prior Palantir FDE/FDSE or comparable customer-embedded role
  • Hands-on MSS experience AIP agent or large language model workflow exposure
  • Familiarity with DoD data environments and classified networks
  • Prior Combatant Command support
  • Solid Python and SQL skills with familiarity in JavaScript/TypeScript 
Working Conditions
Must be able to work onsite in a SCIF
Our Core Values
 
Employees of Agile Defense are our number one priority, and the importance we place on our culture here is fundamental. Our culture is alive and evolving, but it always stays true to its roots. Here, you are valued as a family member, and we believe that we can accomplish great things together. Agile Defense has been highly successful in the past few years due to our employees and the culture we create together. 
 
What makes us Agile? We call it the 6Hs, the values that define our culture and guide everything we do. Together, these values infuse vibrancy, integrity, and a tireless work ethic into advancing the most important national security and critical civilian missions. It's how we show up every day. It's who we are.
 
  • Happy - Be Infectious. Happiness multiplies and creates a positive and connected environment where motivation and satisfaction have an outsized effect on everything we do.
  • Helpful - Be Supportive. Being helpful is the foundation of teamwork, resulting in a supportive atmosphere where collaboration flourishes, and collective success is celebrated.
  • Honest - Be Trustworthy. Honesty serves as our compass, ensuring transparent communication and ethical conduct, essential to who we are and the complex domains we support.
  • Humble - Be Grounded. Success is not achieved alone, humility ensures a culture of mutual respect, encouraging open communication, and a willingness to learn from one another and take on any task.
  • Hungry - Be Eager. Our hunger for excellence drives an insatiable appetite for innovation and continuous improvement, propelling us forward in the face of new and unprecedented challenges.
  • Hustle - Be Driven. Hustle is reflected in our relentless work ethic, where we are each committed to going above and beyond to advance the mission and achieve success.
 
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.