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Python Software Engineer Jobs in Missouri (NOW HIRING)

Depending on your expertise, you may work with Rust, Go, Python, Flutter, C/C++, Linux distributions, packaging systems, or build automation. The position combines hands-on software engineering with ...

Systems Software Engineer

California, MO · On-site

$125 - $150/hr

Extensive experience with C, Rust, and Python * Advanced knowledge of SAS and NVMe protocols ... Python Programming * Software Systems Architecture * Software Systems Testing Methodology

Staff Software Engineer

Saint Louis, MO · On-site

$125 - $150/hr

This role is software engineering first, with a strong emphasis on designing reliable systems that ... Design, develop, and maintain scalable Python applications and backend services. * Build systems ...

Staff Software Engineer

Saint Louis, MO · On-site

$110K - $185K/yr

This role is software engineering first, with a strong emphasis on designing reliable systems that ... Design, develop, and maintain scalable Python applications and backend services. * Build systems ...

Our partner is looking for a Software Engineer - Solutions Engineering based in Netherlands. Join a ... The role combines hands-on Python and Go development with deep exposure to the Linux stack, from ...

Writing and debugging code in languages such as C#, Java, Python, or C++ * Participating on an ... Software Engineering, Biomedical Engineering (with computational focus), or related field

Writing and debugging code in languages such as C#, Java, Python, or C++ * Participating on an ... Software Engineering, Biomedical Engineering (with computational focus), or related field

Writing and debugging code in languages such as C#, Java, Python, or C++ * Participating on an ... Software Engineering, Biomedical Engineering (with computational focus), or related field

Job Title: Software Engineer Location: St. Louis, MO Security Clearance: Active TS/SCI (or SCI ... Hands-on experience with Python in production application development environments or building ...

Writing and debugging code in languages such as C#, Java, Python, or C++ * Participating on an ... Software Engineering, Biomedical Engineering (with computational focus), or related field

Showing results 21-40

Python Software Engineer information

See Missouri salary details

$21.6K

$131.3K

$189.9K

How much do python software engineer jobs pay per year?

As of Sep 8, 2026, the average yearly pay for python software engineer in Missouri is $131,293.00, according to ZipRecruiter salary data. Most workers in this role earn between $103,600.00 and $154,300.00 per year, depending on experience, location, and employer.

What is a Python software engineer?

A Python Software Engineer is a developer who designs, develops, and maintains software applications using the Python programming language. They work on a variety of tasks, including writing clean and efficient code, debugging, optimizing performance, and integrating third-party services or APIs. Python engineers often collaborate with teams to build web applications, data pipelines, machine learning models, or automation scripts, depending on the industry. Their role requires strong problem-solving skills and familiarity with software development best practices.

What does a Python software engineer do?

A typical workday for a Python Software Engineer involves writing and testing code, participating in team meetings to plan and review tasks, and collaborating with colleagues such as front-end developers, quality assurance engineers, and project managers. You may spend time troubleshooting bugs, reviewing pull requests, and improving existing software modules. Many teams use Agile or Scrum methodologies, so your day may include short stand-up meetings and iterative development cycles. Depending on the company, you might also have opportunities to contribute to design discussions or mentor junior developers.

What skills and qualifications are needed to be a Python software engineer?

To thrive as a Python Software Engineer, you need strong programming skills in Python, a solid understanding of algorithms and data structures, and a relevant degree in computer science or related fields. Experience with frameworks like Django or Flask, familiarity with version control systems such as Git, and optional certifications like PCEP or PCAP can be valuable assets. Problem-solving skills, teamwork, and effective communication help you navigate complex projects and collaborate efficiently. Mastering both technical and soft skills is crucial for building reliable software solutions and succeeding in dynamic development teams.

Are Python Software Engineers in demand?

Python Software Engineers are in high demand across various industries due to Python's versatility in web development, data analysis, machine learning, and automation. Employers seek professionals with strong programming skills, experience with frameworks like Django or Flask, and knowledge of data tools, making it a valuable skill set for many tech roles.

Can I be a Python Software Engineer with Python?

Yes, Python is the primary programming language used by Python Software Engineers. Proficiency in Python, along with knowledge of related tools like version control systems and frameworks, is essential for this role. Typically, a bachelor's degree in computer science or a related field and experience with software development are also required.

How much do Python software engineers make?

Python software engineers' salaries vary based on experience, location, and industry, but the median annual salary in many regions ranges from $80,000 to $130,000. Senior roles or those with specialized skills in frameworks like Django or data analysis can earn higher compensation, often exceeding $150,000 annually.

What are the most commonly searched types of Python Software Engineer jobs in Missouri?

The most popular types of Python Software Engineer jobs in Missouri are:

What are popular job titles related to Python Software Engineer jobs in Missouri?

For Python Software Engineer jobs in Missouri, the most frequently searched job titles are:

What job categories do people searching Python Software Engineer jobs in Missouri look for?

The top searched job categories for Python Software Engineer jobs in Missouri are:

What are popular job titles related to Python Software Engineer jobs in MO?

For Python Software Engineer jobs in MO, the most frequently searched job titles are:

Infographic showing various Python Software Engineer job openings in Missouri as of August 2026, with employment types broken down into 1% As Needed, 84% Full Time, 10% Part Time, and 5% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $131,293 per year, or $63.1 per hour.

Software Engineer

California, MO • On-site

$100 - $125/hr

Other

Medical, Retirement, PTO

Posted 10 days ago


Job description

Description

Leidos Defense is seeking a Senior Software Engineer to join our team in our San Diego facility, supporting the U.S. Navy’s AN/SQQ-89(V) Anti-Submarine Warfare (ASW) systems.

Our program helps modernize Navy ships by replacing outdated sonar systems with updated AN/SQQ-89(V)15 systems, supporting the installation, logistics, quality checks, and training needed to prepare ship personnel to operate the new systems.

In this role, you will focus on modernizing the AN/SQQ-89(V) ASW Training System by transitioning Tactical Insertion (TI) hardware-based solutions to a scalable, virtualized Linux training platform. You’ll work with Red Hat Enterprise Linux (RHEL), KVM, Open vSwitch, Python, Ansible, and hardware passthrough technologies to support complex Navy training and simulation environments.

What You'll Do
  • Design, deploy, and maintain virtualized environments supporting AN/SQQ-89(V)15 training capabilities.

  • Migrate software and services from Tactical Insertion hardware platforms to virtualized environments using KVM, libvirt, virsh, and VirtIO.

  • Build and maintain RHEL 7/8 system images, templates, and repositories.

  • Develop automated deployment and configuration solutions using Ansible.

  • Create Python utilities and scripts for system administration, testing, monitoring, and data management.

  • Configure and maintain Open vSwitch environments supporting multiple networks and high-throughput virtual machine communications.

  • Integrate physical and virtual networking within tactical training environments.

  • Troubleshoot complex virtualization, Linux, networking, storage, hardware, and application integration issues.

  • Support performance tuning and optimization of virtualized systems, networking, storage, and compute resources.

  • Support software integration, system verification, validation, and acceptance testing.

  • Collaborate with software developers, systems engineers, cybersecurity personnel, and training system stakeholders.

  • Support cybersecurity compliance activities, including STIG implementation, vulnerability remediation, and RMF activities.

  • Develop and maintain architecture diagrams, deployment guides, standard operating procedures, and automation documentation.

  • Support modernization efforts focused on improving the portability, scalability, and maintainability of training environments.

What We're Looking For
  • Bachelor's degree with 4–8 years of relevant experience, or a Master's degree with 2–6 years of relevant experience.

  • Experience with Linux systems engineering, virtualization, software development, or platform engineering.

  • Experience administering Red Hat Enterprise Linux (RHEL) environments.

  • Strong experience with KVM, libvirt, and virsh.

  • Experience implementing and troubleshooting Open vSwitch (OVS).

  • Experience with hardware passthrough technologies, including PCIe passthrough, VFIO, SR-IOV, and IOMMU configuration.

  • Experience developing infrastructure automation using Ansible.

  • Experience developing software and automation tools using Python.

  • Strong understanding of Linux networking concepts, including VLANs, bridges, routing, bonding, and virtual switching.

  • Experience troubleshooting integration issues across hardware, operating systems, networking, and applications.

  • Ability to obtain and maintain a DoD security clearance.

Preferred Qualifications
  • Experience supporting AN/SQQ-89(V)15 or AEGIS combat systems.

  • Red Hat Certified Engineer (RHCE).

  • Experience with high-performance networking and low-latency virtualized environments.

  • Experience supporting GPU, FPGA, capture card, or other specialized hardware passthrough to virtual machines.

  • Familiarity with distributed storage, NFS, iSCSI, and SAN technologies.

  • Experience with FreeIPA, LDAP, Kerberos, and enterprise Linux identity management.

  • Experience supporting RMF, STIG implementation, ACAS, and cybersecurity compliance initiatives.

  • Active Secret or Top Secret clearance.

If you have a strong Linux and virtualization background and are interested in applying those skills to modernize U.S. Navy training systems,

If you're looking for comfort, keep scrolling. At Leidos, we outthink, outbuild, and outpace the status quo — because the mission demands it. We're not hiring followers. We're recruiting the ones who disrupt, provoke, and refuse to fail. Step 10 is ancient history. We're already at step 30 — and moving faster than anyone else dares.

Pay Range

Pay Range $87,100.00 - $157,450.00

The Leidos pay range for this job level is a general guideline onlyand not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law.

About Leidos

Leidos is an industry and technology leader serving government and commercial customers with smarter, more efficient digital and mission innovations. Headquartered in Reston, Virginia, with 47,000 global employees, Leidos reported annual revenues of approximately $16.7 billion for the fiscal year ended January 3, 2025. For more information, visit www.Leidos.com.

Pay and Benefits

Pay and benefits are fundamental to any career decision. That's why we craft compensation packages that reflect the importance of the work we do for our customers. Employment benefits include competitive compensation, Health and Wellness programs, Income Protection, Paid Leave and Retirement. More details are available at www.leidos.com/careers/pay-benefits.

Securing Your Data

Beware of fake employment opportunities using Leidos’ name. Leidos will never ask you to provide payment-related information during any part of the employment application process (i.e., ask you for money), nor will Leidos ever advance money as part of the hiring process (i.e., send you a check or money order before doing any work). Further, Leidos will only communicate with you through emails that are generated by the Leidos.com automated system – never from free commercial services (e.g., Gmail, Yahoo, Hotmail) or via WhatsApp, Telegram, etc. If you received an email purporting to be from Leidos that asks for payment-related information or any other personal information (e.g., about you or your previous employer), and you are concerned about its legitimacy, please make us aware immediately by emailing us at LeidosCareersFraud@leidos.com.

If you believe you are the victim of a scam, contact your local law enforcement and report the incident to the U.S. Federal Trade Commission.

Commitment to Non-Discrimination

All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.

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