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Python Software Developer Jobs in Charleston, SC

Software/ Data Engineer

North Charleston, SC · Hybrid

$109K - $131K/yr

NET Application Developer to design, develop, and maintain console-based applications that ... Nice to have: experience with web development , Python , and Git (relevant for future initiatives)

Showing results 21-40

Python Software Developer information

See Charleston, SC salary details

$12

$54

$80

How much do python software developer jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for python software developer in Charleston, SC is $54.86, according to ZipRecruiter salary data. Most workers in this role earn between $45.19 and $62.31 per hour, depending on experience, location, and employer.

What is a python software developer?

Python Software Developers are professionals who design, develop, and maintain software applications using the Python programming language. They are responsible for writing efficient and reusable code, debugging and resolving software issues, and collaborating with other team members to deliver software solutions. Python Software Developers may work on web development, data analysis, automation, artificial intelligence, and more, depending on the needs of their employer or clients. Their expertise in Python allows them to build scalable and flexible software systems.

What are the key skills and qualifications needed to thrive as a python software developer?

To thrive as a Python Software Developer, you need strong programming skills in Python, a solid understanding of algorithms and data structures, and a relevant degree or equivalent experience. Familiarity with frameworks like Django or Flask, version control systems such as Git, and experience with databases and cloud platforms are typically required. Problem-solving ability, attention to detail, and effective communication help developers collaborate on complex projects and deliver robust solutions. These skills ensure the creation of efficient, maintainable code and successful teamwork in dynamic development environments.

What does collaboration typically look like for a python software developer within a development team?

As a Python Software Developer, you'll frequently collaborate with other developers, QA engineers, project managers, and sometimes UI/UX designers. This often involves participating in daily stand-ups, code reviews, and pair programming sessions to ensure code quality and alignment with project goals. Effective communication is key, as you'll need to discuss technical solutions, clarify requirements, and provide feedback. Additionally, you'll likely use tools like Git, Jira, and Slack to coordinate tasks and track progress within an agile workflow.

What is the difference between Python Software Developer vs Python Data Analyst?

AspectPython Software DeveloperPython Data Analyst
Required CredentialsBachelor's in CS or related field, programming certificationsBachelor's in Statistics, Data Science, or related field, data analysis certifications
Work EnvironmentSoftware development teams, tech companies, startupsData teams, business intelligence units, research departments
Employer & Industry UsageTech firms, finance, healthcare, e-commerceMarket research, finance, marketing, consulting
Common Search & ComparisonYesYes

Python Software Developers focus on building applications, APIs, and software solutions using Python, while Python Data Analysts analyze data sets to generate insights. Both roles require Python programming skills and often overlap in data handling, but their core responsibilities and industry applications differ.

Are Python software developers in demand?

Python software developers are in high demand across various industries due to the language's versatility, ease of use, and widespread adoption in web development, data analysis, machine learning, and automation. Employers seek professionals skilled in frameworks like Django and Flask, as well as proficiency with tools such as Git and cloud platforms. The demand is expected to grow as technology continues to evolve and reliance on Python-based solutions increases.

Is Python still in demand in 2026?

Python software developers remain in high demand in 2026 due to Python's widespread use in data science, machine learning, web development, and automation. Proficiency in frameworks like Django or Flask and knowledge of related tools continue to enhance job prospects in this field.

What jobs can a Python Software Developer get?

A Python Software Developer can pursue roles such as backend developer, data analyst, data scientist, machine learning engineer, automation engineer, or software engineer. These positions often require knowledge of frameworks like Django or Flask, and familiarity with databases, version control, and cloud platforms is beneficial.

Which Python Software Developer job is in demand?

Python Software Developer roles are in high demand across industries such as technology, finance, and healthcare, especially for positions requiring expertise in frameworks like Django or Flask, data analysis, and automation. Skills in cloud platforms, machine learning, and version control tools like Git can enhance job prospects in this field.

What are popular job titles related to Python Software Developer jobs in Charleston, SC?

For Python Software Developer jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Python Software Developer jobs in Charleston, SC look for?

The top searched job categories for Python Software Developer jobs in Charleston, SC are:

Infographic showing various Python Software Developer job openings in Charleston, SC as of August 2026, with employment types broken down into 85% Full Time, 10% Part Time, and 5% Contract. Highlights an 76% In-person, and 24% Remote job distribution, with an average salary of $114,107 per year, or $54.9 per hour.

Senior Software Engineer

Charles River Laboratories, Inc.

Charleston, SC • On-site

$128K - $133K/yr

Full-time

Medical, Retirement, PTO

This job post has expired 2 days ago. Applications are no longer accepted.


Charles River Laboratories rating

8.3

Company rating: 8.3 out of 10

Based on 95 frontline employees who took The Breakroom Quiz

23rd of 86 rated pharmaceutical


Job description

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.

Job Overview

The Senior Software Engineer serves as a technical lead role and is responsible for developing the design and architecture of the interaction between various subsystems and applications. This position is a combination ofadvisory and hands-on involvement on unique custom software development projects for both internal and commercial projects. The senior software engineer will work in conjunction with our System Integration and Software Development teams, responsible to build, improve key features that are integral to our customers,enhance architecture, design, scalability and performance of our existing and new platforms. Extensive knowledgeof .NET, C#, and React.js, PostgreSQL database is critical for the success of the senior software engineer.


Essential Duties and Responsibilities:
Design, develop, test, deploy, maintain, and enhance the internal and commercial software that controls and automates laboratory devices.
Conduct and participate in design, code, and test reviews
Participate in all phases of existing/new software development, including system requirement specification,design, implementation, software integration and testing.
Prepare appropriate documentation as required by internal product development processes and regulatory agencies (FDA and ISO regulations)

Qualifications

Education:
Bachelor's Degree in Computer Science or equivalent Engineering skillset and work experience in SoftwareEngineering
Experience:
5 years of extensive programming experience, including .NET/ASP.NET, C#, Python and GIT experience is required.
Understanding of how to translate complex systems into sub-components and optimizing the design of both.
Experience in a regulated software development environment is desirable.
Experience with cloud programming like Azure/AWS is desirable.
Knowledge of continuous integration system (Azure DevOps) to automate application builds, testing, anddeployments to web servers, is optional
Skills and Abilities:
Excellent critical systems integration thinking, attention to detail, ability to prioritize and work on multiple projectsin a fast-paced, changing environment
Highly motivated self-starter with a desire to help others and act
Possess a strong communication skill, including written, verbal and presentation in English
Knowledge in open-source software engineering

The pay range for this position is $128,000-$133,000. Please note that salaries vary within the range based onfactors including, but not limited to, experience, skills, education, certifications, and location.

About Microbial Solutions
Our Microbial Solutions business group has a comprehensive portfolio of endotoxin testing, microbial detection and microbial identification products and services is unlike any other, and has been purposefully designed to meet the complex and ever-changing needs of the industry. We help clients to ensure product safety and quality with easy-to-use yet robust testing solutions that satisfy regulatory requirements, support critical decision making and improve operational efficiencies.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increased to $2.62 billion.

At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 80% of the drugs approved by the FDA in the last five years.

We're committed to providing benefits that elevate your quality of life.  Based on your position these may include:  bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment Opportunity
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.

It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.


What Charles River Laboratories employees say

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Benefits

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About Charles River

Sourced by ZipRecruiter

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

Wilmington, MA, US

Year founded

1947