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Python Bioinformatics Jobs in California (NOW HIRING)

Arc Institute

Scientist, Bioinformatics

Palo Alto, CA · On-site

... Python, git/GitHub, and Linux. • Strong statistical, mathematical, and data science skills ... bioinformatics software, including writing tests, documentation, and versioned releases. • ...

Natera

Senior Bioinformatics Scientist

San Carlos, CA · On-site

Strong Python programming skills, including fluency with the scientific computing stack (NumPy ... scalable bioinformatics pipelines. * Extensive experience in distributed computing and cloud ...

Roche

Sr. Manager, Bioinformatics

Santa Clara, CA · Hybrid

$170K - $316K/yr

... Python, R). * You have demonstrated experience in product commercialization, go-to-market execution, or technical customer enablement (similar to scaling platforms like DRAGEN). Preferred: * You have ...

Roche

Sr. Manager, Bioinformatics

San Diego, CA · Hybrid

$170K - $316K/yr

... Python, R). * You have demonstrated experience in product commercialization, go-to-market execution, or technical customer enablement (similar to scaling platforms like DRAGEN). Preferred: * You have ...

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All JobsPython Bioinformatics JobsPython Bioinformatics Jobs in California

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$13

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How much do python bioinformatics jobs pay per hour?

As of Jul 2, 2026, the average hourly pay for python bioinformatics in California is $57.85, according to ZipRecruiter salary data. Most workers in this role earn between $47.69 and $65.72 per hour, depending on experience, location, and employer.

What is a Python Bioinformatics job?

A Python Bioinformatics job involves using Python programming to analyze and interpret biological data, such as DNA sequences, protein structures, and genomic information. Professionals in this role develop algorithms, write scripts, and use bioinformatics libraries like Biopython to process large datasets efficiently. They often work in research institutions, pharmaceutical companies, or healthcare organizations to support scientific discoveries and advancements in medicine. Strong skills in Python, data analysis, and computational biology are essential for success in this field.

What does a typical workday look like for a Python Bioinformatics professional?

A typical workday for a Python Bioinformatics professional often involves developing and maintaining data analysis pipelines, processing large biological datasets, and interpreting results in collaboration with biologists and other researchers. You'll spend substantial time writing scripts, troubleshooting code, and integrating different bioinformatics tools to address specific research questions. Team meetings and presentations are common, as the role requires frequent interaction with cross-functional colleagues. This dynamic environment offers the opportunity to stay engaged with new technologies and make meaningful contributions to scientific discovery.

What are the key skills and qualifications needed to thrive in the Python Bioinformatics position, and why are they important?

To thrive as a Python Bioinformatics professional, you need a strong foundation in biological sciences, proficiency in Python programming, and experience analyzing complex biological datasets. Familiarity with bioinformatics tools such as Biopython, BEDtools, and databases like NCBI, as well as knowledge of cloud computing platforms and relevant certifications, is commonly expected. Strong problem-solving abilities, attention to detail, and effective communication skills help you collaborate with interdisciplinary teams. These competencies are vital for interpreting biological data accurately, developing reliable pipelines, and advancing research objectives.

What are popular job titles related to Python Bioinformatics jobs in California? For Python Bioinformatics jobs in California, the most frequently searched job titles are:
What job categories do people searching Python Bioinformatics jobs in California look for? The top searched job categories for Python Bioinformatics jobs in California are:
What cities in California are hiring for Python Bioinformatics jobs? Cities in California with the most Python Bioinformatics job openings:
Python Bioinformatics jobs near you
Infographic showing various Python Bioinformatics job openings in California as of June 2026, with employment types broken down into 89% Full Time, 7% Part Time, 1% Temporary, and 3% Contract. Highlights an 82% Physical, 5% Hybrid, and 13% Remote job distribution, with an average salary of $120,336 per year, or $57.9 per hour.
Principal Scientist, Bioinformatics

Principal Scientist, Bioinformatics

Nkarta, Inc.

South San Francisco, CA • Hybrid

Other

Posted 17 days ago

Job description

Overview

Nkarta is seeking a highly motivated, collaborative, detail-oriented Principal Scientist to join our Translational Medicine team. This is a high-impact, hands-on leadership role for a senior bioinformatics scientist. The successful candidate will have deep expertise in single-cell and spatial omics technologies, along with experience in functional genomics and leading computational biology and/or bioinformatics programs in a biotech or pharmaceutical setting.

This individual will work collaboratively within Translational Medicine and cross-functionally to advance, support, and execute biomarker discovery, mechanism-of-action (MOA) investigations, and translational data analysis from clinical samples. A central focus of this role is to drive and execute on Nkarta's strategy for single-cell and spatial transcriptomics, leveraging scRNA-seq, spatial, and functional genomics approaches to drive translational insights, biomarker development, and clinical decision-making in early development.

Responsibilities

  • Lead and actively participate in the design and execution of computational strategies and hands-on analysis of clinical and biological datasets to support go/no-go decisions
  • Hands-on development and application of computational methods for single-cell and spatial transcriptomics to generate actionable translational insights from clinical samples
  • Establish scalable pipelines for multi-modal data integration across programs
  • Integrate and analyze functional genomics datasets (e.g., bulk RNA-seq) to generate mechanistic insights that inform translational and clinical strategies
  • Provide high-impact analyses with direct influence on clinical decision-making and visibility to senior leadership
  • Collaborate with senior leadership to define priorities, allocate resouces, and establish timelines aligned with company objectives
  • Partner with experimental scientists to design studies leveraging advanced omics approaches and interpret results
  • Ensure reproducibility, scalability, and data quality across bioinformatics pipelines
  • Communicate complex findings effectively to scientific and non-scientific stakeholders, including senior leadership

Qualifications

  • Deep expertise in single-cell and spatial transcriptomics analysis, including scRNA-seq and related high-dimensional omics datasets
  • Strong experience analyzing functional genomics and transcriptomic data (e.g., bulk RNA-seq, WES) to derive biological and translational insights
  • Strong foundation in biological sciences, with experience or interest in immunology and disease biology
  • Deep understanding of modern statistical and computational methods for high-dimensional data analysis
  • Proficiency in Python and/or R, with experience using relevant bioinformatics frameworks
  • Experience developing and maintaining scalable data analysis pipelines and working with cloud-based infrastructure (e.g., AWS)
  • Excellent communication and presentation skills, with the ability to influence cross-functional stakeholders and translate complex data into clear, actionable insights
  • Demonstrated experience managing external CROs and bioinformatics vendors
  • Proven leadership experience, including mentoring and developing scientific teams
  • Strong cross-functional collaboration skills and ability to translate computational insights into biological and clinical impact
  • Ability to work both independently and collaboratively in a fast-paced environment, with strong organizational skills and attention to detail

Education/Background

  • PhD in Biological Sciences, Computational Biology, Biostatistics, Bioinformatics, Genomics, or a closely related discipline with 5+ years of industry experience.

The common requirements of an office environment (computers, computer screens, workstations, etc.) apply. This role is based in the South San Francisco office, with hybrid work arrangements possible.

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