Protein Purification Jobs in Virginia (NOW HIRING)

The Brayman Lab in the Department of Surgery at the University of Virginia is seeking a Laboratory Specialist Intermediate or Senior to perform and a ssist with studies investigating the underlying mechanisms of type 1 diabetes and recurrence of diabetes in various murine models of diabetes. The position will also support human pancreatic islet i solations in the GMP islet isolation facility.
Responsibilities
Research responsibilities include working with mice and performing/ assisting with in vitro and in vivo experiments related to ongoing studies, including:

• Working with murine models of diabetes, including mouse islet isolation and transplantation

• Surgical procedures

• Isolating islets

• Measuring mouse blood glucose levels

• Collection of mouse tissue, serum, and blood, including collection of mouse tissue and blood for proteomic studies

• Assistance with collection and entry of data in electronic media

• Supporting daily lab activities, maintenance, and general laboratory upkeep

• Ordering/ purchasing materials and supplies, including purchasing through the procurement system

• Other duties as assigned

The ideal candidate is an enthusiastic team-oriented individual with a willingness to learn, collaborate, and take on new challenges . Candidates must be able to:

• Perform routine laboratory data analysis and research procedures

• Independently prepare solutions and reagents

• Perform or learn to work with animal models (including surgical techniques; training provided if necessary)

• Work diligently with strong attention to detail

• Analyze and organize work procedures; plan and execute tasks/experiments; interpret and report findings, writing skills

• Work a flexible schedule when required

• Train in and comply with BSL-2 procedures

• Demonstrate reproducibility and strong critical thinking skills

Minimum Qualifications

• Education: Bachelor's degree required .

• Experience: 3+ years of relevant experience.

Preferred Qualifications

• Experience working actively in a research laboratory; experience in standard cell biology techniques and murine work

• Flow cytometry and CyTOF

• Protein purification (including immunoglobulins such as IgM) and chromatography

• Experience with Akta go FPLC system

• Proteomics

• Experience with mass spectroscopy (LC-MS), glycan preparation, data analysis

• Immunoassays, including ELISAs

• Electrophoresis and Western blot

• PCR, RT-PCR

• DNA and RNA extractions for NGS, RNAseq / scRNAseq / cfRNAseq

• Tissue culture / in vitro cell culture

• Histology analysis and immunostaining of tissue sections to back up imaging mass cytometry

• Immunohistochemistry, Immunofluorescence, Immunocryohistochemistry .

• Stem cells and organoids

• Imaging mass cytometry

• Confocal

• Experience in R and Python, with additional experience in downstream pipeline analysis and additional expertise in statistical and data analysis software

Physical Demands
This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.
Salary Range

• Salary will be commensurate with education and experience.

Position Type & Work Location

• This is an exempt-leve l, benefited position. Learn more about UVA benefits .

• This is a restricted position, which is dependent on funding and is contingent upon funding availability.

• This position has a term limit of 1 year after which continued employment will depend on department need and funding.

• This position is based in Charlottesville, VA, and must be performed fully on-site.

About UVA and the Community
To learn more about UVA and in the Charlottesville area, visit UVA Life and Embark CVA .
Application Timeline
Application review will begin after April 27, 2026.
Additional Requirements

• Background checks and pre-employment health screenings will be conducted on all new hires prior to employment.

• This p osition will not consider candidates who require immigration sponsorship now or in the future.

How to Apply
Please apply online , by searching for requisition number R0082626 .
Internal applicants may search and apply for jobs on the UVA Internal Careers website .
Complete an application with the following documents:

• Resume

• Cover Letter

Upload all materials into the resume submission field . You can submit multiple documents into this one field or combine them into one PDF . Applications without all required documents will not receive full consideration.
Reference Check Process
Reference checks will be completed by UVA's third-party partner, SkillSurvey, during the final phase of the interview. Five references will be requested, with at least three responses required .
Contact

• For q uestions about the application process, please contact Jon Freeman, jf2sw@virginia.edu.

The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA's commitment to non-discrimination and equal opportunity employment .
Each agency within the Commonwealth of Virginia is dedicated to recruiting, supporting, and maintaining a competent and diverse work force. Equal Opportunity Employer