Lab Specialist
Charlottesville, VA · On-site
... in protein design, nanobody development, and structural biology. The Bao Laboratory is advancing the development of engineered protein binders and nanobodies to dissect and modulate membrane ...
Lab Specialist
Charlottesville, VA · On-site
... in protein design, nanobody development, and structural biology. The Bao Laboratory is advancing the development of engineered protein binders and nanobodies to dissect and modulate membrane ...
Lab Specialist
Charlottesville, VA · On-site
... in protein design, nanobody development, and structural biology. The Bao Laboratory is advancing the development of engineered protein binders and nanobodies to dissect and modulate membrane ...
Lab Specialist
Charlottesville, VA · On-site
... in protein design, nanobody development, and structural biology. The Bao Laboratory is advancing the development of engineered protein binders and nanobodies to dissect and modulate membrane ...
Research Associate in Chemical Engineering
Charlottesville, VA · On-site
$57K - $60K/yr
Within this role, the selected candidate will learn to measure protein adsorption isotherms, protein transport parameters in chromatographic resin, design preparative and analytical chromatographic ...
Research Associate in Chemical Engineering
Charlottesville, VA · On-site
$57K - $60K/yr
Within this role, the selected candidate will learn to measure protein adsorption isotherms, protein transport parameters in chromatographic resin, design preparative and analytical chromatographic ...
Postdoctoral Researcher (Chemistry)
Amherst, VA · On-site
$63K - $65K/yr
... design - Familiarity with E. coli-based reporter assays - Next-Generation Sequencing (NGS) sample preparation and data analysis - Protein purification via FPLC - Enzymatic and biophysical assays ...
Postdoctoral Researcher (Chemistry)
Amherst, VA · On-site
$63K - $65K/yr
... design - Familiarity with E. coli-based reporter assays - Next-Generation Sequencing (NGS) sample preparation and data analysis - Protein purification via FPLC - Enzymatic and biophysical assays ...
Research Associate in Chemistry
Charlottesville, VA · On-site
$61K - $64K/yr
These include the development of molecular glues , targeted protein degraders , chemically induced ... The successful applicant will lead the design and synthesis of structurally complex small molecules ...
Research Associate in Chemistry
Charlottesville, VA · On-site
$61K - $64K/yr
These include the development of molecular glues , targeted protein degraders , chemically induced ... The successful applicant will lead the design and synthesis of structurally complex small molecules ...
Research Scientist Biochemistry & Molecular Genetics, Yang Lab
Charlottesville, VA · On-site
$63K - $70K/yr
We combine state-of-the-art cryo-EM, protein biochemistry, biophysics, and cell biology to ... Design and execute experiments, analyze and interpret data, and develop new experimental strategies.
Research Scientist Biochemistry & Molecular Genetics, Yang Lab
Charlottesville, VA · On-site
$63K - $70K/yr
We combine state-of-the-art cryo-EM, protein biochemistry, biophysics, and cell biology to ... Design and execute experiments, analyze and interpret data, and develop new experimental strategies.
Biochemistry Tutor
Leesburg, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Leesburg, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Charlottesville, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Charlottesville, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Alexandria, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Alexandria, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Norfolk, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Norfolk, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Fairfax, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Fairfax, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Blacksburg, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Blacksburg, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Salem, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Salem, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Virginia Beach, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Virginia Beach, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Richmond, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Biochemistry Tutor
Richmond, VA · Remote
$18 - $40/hr
... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...
Lab Research Professional 2 UVA Spiliotis Lab
Charlottesville, VA · On-site
$55K/yr
... a focus on protein biochemistry, and the purification of recombinant proteins using fast performance liquid chromatography (FPLC). * Design and execute molecular cloning projects, and the ...
Lab Research Professional 2 UVA Spiliotis Lab
Charlottesville, VA · On-site
$55K/yr
... a focus on protein biochemistry, and the purification of recombinant proteins using fast performance liquid chromatography (FPLC). * Design and execute molecular cloning projects, and the ...
Lab Research Professional 2 UVA Spiliotis Lab
Charlottesville, VA · On-site
$55K/yr
... a focus on protein biochemistry, and the purification of recombinant proteins using fast performance liquid chromatography (FPLC). * Design and execute molecular cloning projects, and the ...
Lab Research Professional 2 UVA Spiliotis Lab
Charlottesville, VA · On-site
$55K/yr
... a focus on protein biochemistry, and the purification of recombinant proteins using fast performance liquid chromatography (FPLC). * Design and execute molecular cloning projects, and the ...
Utilities Project Engineer
Norfolk, VA · On-site
$90K - $130K/yr
This role focuses on system design, optimization, and compliance, while partnering closely with ... Experience in food or protein manufacturing is preferred * Electrical troubleshooting experience ...
Quick apply
Utilities Project Engineer
Norfolk, VA · On-site
$90K - $130K/yr
This role focuses on system design, optimization, and compliance, while partnering closely with ... Experience in food or protein manufacturing is preferred * Electrical troubleshooting experience ...
Lab Research Professional 2 UVA Spiliotis Lab
Charlottesville, VA · On-site
$55K/yr
... a focus on protein biochemistry, and the purification of recombinant proteins using fast performance liquid chromatography (FPLC). * Design and execute molecular cloning projects, and the ...
Lab Research Professional 2 UVA Spiliotis Lab
Charlottesville, VA · On-site
$55K/yr
... a focus on protein biochemistry, and the purification of recombinant proteins using fast performance liquid chromatography (FPLC). * Design and execute molecular cloning projects, and the ...
AI Scientist- Computational Chemistry at Nature Careers Ashburn, VA
Ashburn, VA · On-site
$180 - $296/hr
Apply AI and computational methods, including generative molecular design, molecular property ... protein engineers. * Adhere to the highest academic, scientific, and ethical standards in all ...
New
AI Scientist- Computational Chemistry at Nature Careers Ashburn, VA
Ashburn, VA · On-site
$180 - $296/hr
Apply AI and computational methods, including generative molecular design, molecular property ... protein engineers. * Adhere to the highest academic, scientific, and ethical standards in all ...
New
Protein Design information
What is protein design?
Protein design is the process of creating new proteins or modifying existing ones to have specific functions or properties. This can involve using computational tools, laboratory techniques, or a combination of both to predict and engineer amino acid sequences that will fold into desired three-dimensional structures. Protein design is used in various fields, including medicine, biotechnology, and research, to develop novel enzymes, therapeutics, or materials. The field requires a strong understanding of biology, chemistry, and computer science to achieve successful outcomes.
What are the key skills and qualifications needed to thrive as a protein design scientist, and why are they important?
To thrive as a Protein Design Scientist, you need a strong background in molecular biology, biochemistry, and computational modeling, typically supported by an advanced degree in a relevant field. Proficiency with tools such as Rosetta, PyMOL, and molecular dynamics simulation software, as well as experience with protein expression and purification techniques, is essential. Analytical thinking, problem-solving, and effective communication are important soft skills to drive innovation and collaborate with interdisciplinary teams. These skills are crucial for designing functional proteins, troubleshooting experiments, and advancing research goals in biotechnology and pharmaceutical development.
What are some typical challenges faced by professionals in protein design, and how are they addressed within a team setting?
Professionals in protein design often encounter challenges such as predicting accurate protein folding, ensuring stability, and achieving desired biological activity. These complexities are typically addressed through close collaboration with computational biologists, structural biologists, and experimental scientists. Teams frequently hold cross-functional meetings to troubleshoot issues, share findings, and iterate on design strategies based on laboratory results. This collaborative environment helps leverage diverse expertise and accelerates the development of novel proteins with desired functions.
What is the difference between Protein Design vs Protein Engineering?
| Aspect | Protein Design | Protein Engineering |
|---|---|---|
| Required Credentials | Biochemistry, Molecular Biology, Bioinformatics | Biochemistry, Molecular Biology, Bioinformatics |
| Work Environment | Research labs, biotech companies, academia | Research labs, biotech companies, academia |
| Industry Usage | Designing novel proteins, drug development, synthetic biology | Modifying existing proteins for improved function or stability |
Protein Design focuses on creating new proteins with specific functions, often using computational methods. Protein Engineering involves modifying existing proteins to enhance or alter their properties. Both roles require similar skills and are used in research, biotech, and pharmaceutical industries, but their goals differ: one designs from scratch, the other optimizes existing proteins.
What are popular job titles related to Protein Design jobs in Virginia?
For Protein Design jobs in Virginia, the most frequently searched job titles are:
- Molecular Laboratory Technologist
- Entry Level Mining Laboratory Technician
- Laboratory Scientist
- Plant Tissue Culture Lab Technician
- Freelance Clinical Data Scientist
- Chemistry Lab Technician
- Capital One Data Scientist
- Entry Level Clinical Laboratory Scientist
- Associate Environmental Scientist
- Work From Home Medical Laboratory Scientist
What job categories do people searching Protein Design jobs in Virginia look for?
The top searched job categories for Protein Design jobs in Virginia are:
What cities in Virginia are hiring for Protein Design jobs?
Cities in Virginia with the most Protein Design job openings:
University Of Virginia rating
7.9
Based on 35 frontline employees who took The Breakroom Quiz
208th of 620 rated colleges and universities
Job description
The Bao Laboratory in the Department of Molecular Physiology and Biological Physics at the University of Virginia School of Medicine is seeking a Laboratory Specialist to support research in protein design, nanobody development, and structural biology.
The Bao Laboratory is advancing the development of engineered protein binders and nanobodies to dissect and modulate membrane-associated signaling and protein aggregation processes relevant to neurodegeneration and cancer. The new Lab Specialist will be responsible for designing, expressing, and purifying recombinant proteins and nanobodies, as well as assisting with biophysical and structural characterization using techniques such as cryo-electron microscopy (cryo-EM), X-ray crystallography, and fluorescence spectroscopy.
This position is essential to sustain the technical innovation, reproducibility, and productivity of our multidisciplinary efforts integrating protein engineering, membrane biochemistry, and structural biology.
Minimum Qualifications:
Preferred Qualifications:
Physical Demands: This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other benchwork and animal procedures requiring fine finger manipulation.
This is a restricted position; continuation is dependent on funding and satisfactory performance.
This position is located in Charlottesville, Virginia. This is a full-time benefited position. For more information on the benefits at UVA, visit www.hr.virginia.edu/benefits .
Compensation: The anticipated hiring range is commensurate with education and experience.
The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.
Application Process:
Please apply online , and search for R0082650. Internal applicants may search and apply for jobs on the UVA Internal Careers website . Complete an application online with the following documents:
Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all the required documents will not receive full consideration. This position is open until filled.
References will be completed via UVA's standardized process SkillSurvey. A total of five references will be requested via SkillSurvey during the final phase of the interview process. A minimum of three are required.
For information regarding the position or the application process, please contact Jessica Speth, Academic Recruiter, js9rk@virginia.edu.
The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA's commitment to non-discrimination and equal opportunity employment .
The Bao Laboratory is advancing the development of engineered protein binders and nanobodies to dissect and modulate membrane-associated signaling and protein aggregation processes relevant to neurodegeneration and cancer. The new Lab Specialist will be responsible for designing, expressing, and purifying recombinant proteins and nanobodies, as well as assisting with biophysical and structural characterization using techniques such as cryo-electron microscopy (cryo-EM), X-ray crystallography, and fluorescence spectroscopy.
This position is essential to sustain the technical innovation, reproducibility, and productivity of our multidisciplinary efforts integrating protein engineering, membrane biochemistry, and structural biology.
Minimum Qualifications:
- Education: Bachelor's degree; may accept combination of experience/education/certification in lieu of degree.
- Experience: 1+ year of relevant lab experience required.
Preferred Qualifications:
- Bachelor's degree in biological sciences
- 3+ years of relevant experience in a research laboratory
Physical Demands: This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other benchwork and animal procedures requiring fine finger manipulation.
This is a restricted position; continuation is dependent on funding and satisfactory performance.
This position is located in Charlottesville, Virginia. This is a full-time benefited position. For more information on the benefits at UVA, visit www.hr.virginia.edu/benefits .
Compensation: The anticipated hiring range is commensurate with education and experience.
The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.
Application Process:
Please apply online , and search for R0082650. Internal applicants may search and apply for jobs on the UVA Internal Careers website . Complete an application online with the following documents:
- CV/Resume
- Cover Letter
Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all the required documents will not receive full consideration. This position is open until filled.
References will be completed via UVA's standardized process SkillSurvey. A total of five references will be requested via SkillSurvey during the final phase of the interview process. A minimum of three are required.
For information regarding the position or the application process, please contact Jessica Speth, Academic Recruiter, js9rk@virginia.edu.
The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA's commitment to non-discrimination and equal opportunity employment .
What University Of Virginia employees say
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About University of Virginia
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The University of Virginia is distinctive among institutions of higher education. Founded by Thomas Jefferson in 1819, the University sustains the ideal of developing, through education, leaders who are well-prepared to shape the future of the nation.
Industry
Colleges, universities, and professional schools
Company size
10,000+ Employees
Headquarters location
Charlottesville, VA, US
Year founded
1819