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Protein Engineer Jobs in Madison, WI (NOW HIRING)

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Protein Engineer information

See Madison, WI salary details

$23.3K

$89.3K

$162.1K

How much do protein engineer jobs pay per year?

As of Jul 27, 2026, the average yearly pay for protein engineer in Madison, WI is $89,346.00, according to ZipRecruiter salary data. Most workers in this role earn between $61,169.00 and $112,629.00 per year, depending on experience, location, and employer.

What are the typical daily tasks and projects for a Protein Engineer?

Protein Engineers typically spend their days designing and conducting experiments to modify and improve protein characteristics, analyzing data from assays, and collaborating with cross-functional teams such as molecular biologists and biochemists. Their work often involves using specialized laboratory equipment, computational modeling tools, and maintaining detailed records of their experimental results. Projects may include developing enzymes for industrial processes, optimizing therapeutic proteins, or engineering innovative biomaterials. The pace can be dynamic, with a mix of independent bench work and group meetings to discuss progress, troubleshoot challenges, and plan next steps. This collaborative environment offers opportunities to learn from peers and contribute to cutting-edge scientific advancements.

What are the key skills and qualifications needed to thrive in the Protein Engineer position, and why are they important?

To thrive as a Protein Engineer, you need expertise in molecular biology, biochemistry, and protein structure-function analysis, often supported by an advanced degree in a relevant scientific field. Familiarity with tools such as protein modeling software, high-throughput screening systems, and genetic engineering techniques is commonly required. Attention to detail, strong analytical thinking, and effective teamwork are valuable soft skills in this role. These abilities are crucial for designing, optimizing, and testing proteins with desired properties, ensuring impactful contributions to research or product development.

What does a Protein Engineer do?

A Protein Engineer designs and modifies proteins for specific functions in fields like medicine, biotechnology, and bioengineering. They use computational modeling, molecular biology techniques, and biochemical assays to improve protein stability, activity, or binding properties. Their work is crucial for developing new therapeutics, enzymes, and biomaterials for various industries.

What are popular job titles related to Protein Engineer jobs in Madison, WI? For Protein Engineer jobs in Madison, WI, the most frequently searched job titles are:
What job categories do people searching Protein Engineer jobs in Madison, WI look for? The top searched job categories for Protein Engineer jobs in Madison, WI are:
Infographic showing various Protein Engineer job openings in Madison, WI as of July 2026, with employment types broken down into 89% Full Time, 8% Part Time, and 3% Contract. Highlights an 86% Physical, 4% Hybrid, and 10% Remote job distribution, with an average salary of $89,346 per year, or $43 per hour.
Reliability Engineer

$104K - $131K/yr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 2 hours ago


Job description

Join our team at Scientific Protein Laboratories (SPL), a world leader in biosourced pharmaceuticals, located just outside of Madison, Wisconsin in Waunakee!  SPL is an innovative biopharmaceutical leader with unique products and services supporting the pharmaceutical industry globally.  For over 40 years, SPL specializes in the development and cGMP compliant manufacturing of Active Pharmaceutical Ingredients (APIs).  

 The primarily function of the Reliability Engineer is reliability analysis, PM optimization, failure elimination, asset lifecycle technical support.  This position will also provide technical leadership to experienced mechanical maintenance technicians driving reliability initiatives into daily work.  The Reliability Engineer will eliminate repeat failures and optimize maintenance strategies so that production equipment operates reliably, PM resources are focused on what matters most, and unplanned downtime is continuously reduced.

 Responsibilities include:

  • Reliability analysis and failure elimination (RCA, FMEA, Bad Actor analysis)
  • PM program technical ownership (categorization, task optimization, interval management)
  • Predictive maintenance program development and oversight (vibration, thermography, oil analysis, ultrasound)
  • Asset lifecycle management (LCAM) technical support for new/modified installations
  • Direct supervision of Engineering Technicians; daily work coordination supported by 1st Shift Maintenance Supervisor
  • Identification and leadership of reliability-driven capital projects
  • Change control leadership for reliability improvements on GMP equipment
  • Own PM categorization assessments using risk-based methodology (severity, occurrence, detection); coordinate Quality-critical PM reviews with QA
  • Lead Root Cause Analysis (RCA) for significant/repeat failures; drive CAPA implementation to closure
  • Conduct FMEA on critical assets to identify failure modes and optimize PM strategies
  • Identify and manage "Bad Actors" (chronic problem equipment); develop and track elimination plans
  • Develop and refine predictive maintenance (PdM) program; analyze trends and recommend interventions before failure
  • Provide reliability input to capital projects (design reviews, acceptance criteria, commissioning plans) per LCAM process
  • Identify, propose, and lead capital projects that improve equipment reliability or eliminate chronic failure modes
  • Lead change control efforts to implement reliability improvements on GMP equipment
  • Partner with Maintenance Planning to ensure PM task content and intervals are technically sound and value-added
  • Supervise and develop Engineering Technicians; provide technical guidance on complex troubleshooting and reliability best practices
  • Provide technical support to Production, Maintenance, and other technical personnel as needed
  • Analyze CMMS data for reliability trends, downtime drivers, and improvement priorities, report findings to Maintenance, Facilities & Asset Systems Manager Utilizes good housekeeping 

Job Requirements and Qualifications:

  • Experience: Required- 2+years, Preferred-10+years

 

  • Education: Required- Associate’s degree or above in Engineering (Chemical, Electrical, Mechanical, Industrial, Reliability) or related discipline, or equivalent experience.  Preferred- Bachelor’s degree or above in Engineering (Chemical, Electrical, Mechanical, Industrial, Reliability) or related discipline.

Schedule:

  • 1st shift

 WHY JOIN SPL?

Our employees are our success!  We recruit motivated people, recognize their contributions, and support their development to reach their full potential. 

 Perks include: competitive compensation; excellent benefits package - including Medical, Dental and Vision on Day 1; Life and AD&D Insurance, and Short and Long-term Disability; Health and Flexible Saving Account options; Employee Assistance Program, generous vacation; paid Holidays; 401k; advancement opportunities; team-oriented environment; community involvement; company events and more!

SPL is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, color, creed, disability, gender identity, national origin, protected veteran status, race, religion, sex, sexual orientation, and any other status protected by applicable local, state or federal law.