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Protein Engineering Scientist Jobs in Madison, WI

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Protein Engineering Scientist information

See Madison, WI salary details

$40.8K

$99.5K

$157.7K

How much do protein engineering scientist jobs pay per year?

As of Aug 30, 2026, the average yearly pay for protein engineering scientist in Madison, WI is $99,512.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,600.00 and $116,900.00 per year, depending on experience, location, and employer.

What is a protein engineering scientist?

A Protein Engineering Scientist designs and optimizes proteins for specific applications using techniques like directed evolution and computational modeling. They work in biotechnology, pharmaceuticals, or academic research to develop enzymes, antibodies, or therapeutic proteins. Their role includes molecular biology, structural analysis, and laboratory experimentation to improve protein function, stability, or specificity.

What are the typical day-to-day responsibilities of a protein engineering scientist?

As a Protein Engineering Scientist, your daily responsibilities often include designing and executing experiments to modify protein structures, analyzing biochemical data, and troubleshooting experimental results. You’ll regularly use both laboratory techniques and computational tools to optimize protein properties, document your findings, and present data to project teams. Collaboration is a key part of the role, so you’ll frequently interact with colleagues from molecular biology, bioinformatics, and downstream process development groups. This dynamic environment keeps the work intellectually stimulating and offers ongoing opportunities to learn from multidisciplinary teams.

What are the key skills and qualifications needed to thrive as a protein engineering scientist?

To thrive as a Protein Engineering Scientist, you need a strong background in molecular biology, biochemistry, and protein design, typically demonstrated through an advanced degree (MSc or PhD) in a life science field. Experience with techniques such as site-directed mutagenesis, protein expression and purification, and familiarity with analytical tools like HPLC, mass spectrometry, and relevant bioinformatics software is essential. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills set top candidates apart. Mastery of these areas is crucial for efficiently designing, optimizing, and characterizing proteins that meet organizational and research goals.

What are the most commonly searched types of Protein Engineering Scientist jobs in Madison, WI?

The most popular types of Protein Engineering Scientist jobs in Madison, WI are:

What are popular job titles related to Protein Engineering Scientist jobs in Madison, WI?

For Protein Engineering Scientist jobs in Madison, WI, the most frequently searched job titles are:

What job categories do people searching Protein Engineering Scientist jobs in Madison, WI look for?

The top searched job categories for Protein Engineering Scientist jobs in Madison, WI are:

Infographic showing various Protein Engineering Scientist job openings in Madison, WI as of August 2026, with employment types broken down into 86% Full Time, 9% Part Time, 2% Temporary, 2% Contract, and 1% Nights. Highlights an 83% Physical, 4% Hybrid, and 13% Remote job distribution, with an average salary of $99,512 per year, or $47.8 per hour.

Process Development Engineer

Waunakee, WI • On-site

$85 - $125/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 7 hours ago


Job description

Job DetailsJob Location: Scientific Protein Laboratories - Waunakee, WI 53597Position Type: Full TimeEducation Level: 4 Year DegreeJob Shift: DayJob Category: EngineeringJOB SUMMARY

Join our team at Scientific Protein Laboratories (SPL), a world leader in biosourced pharmaceuticals, located just outside of Madison, Wisconsin in Waunakee!SPL is an innovative biopharmaceutical leader with unique products and services supporting the pharmaceutical industry globally. For over 40 years, SPL specializes in the development and cGMP compliant manufacturing of Active Pharmaceutical Ingredients (APIs).SPL has an exciting opportunity to join the team as a Process Development Engineer.

Responsibilities
  • Lead the scale-up and technology transfer of new product manufacturing processes from laboratory and pilot-scale development to commercial manufacturing.
  • Implement, and optimize commercial manufacturing processes to ensure product quality, process robustness, and operational efficiency.
  • Identify process equipment and operating parameters for new manufacturing processes. Collaborate with Engineering and external equipment vendors to evaluate and implement manufacturing technologies.
  • Prepare process flow diagrams (PFDs), mass balances, process analyses, expected yield calculations, and manufacturing instructions.
  • Design, coordinate, and execute engineering batches to support process development, process optimization, and technology transfer activities.
  • Prepare technical reports, development protocols, SOPs, equipment operating instructions, and other engineering and manufacturing documentation.
  • Analyze manufacturing and production data to identify trends, improve process performance, maximize yields, and proactively prevent manufacturing issues.
  • Provide technical support for manufacturing operations, including troubleshooting, deviation investigations, root cause analysis, and implementation of corrective and preventive actions (CAPAs).
  • Support the qualification and validation of manufacturing equipment and processes, including IQ, OQ, and PQ activities.
  • Train Operations personnel on new manufacturing processes, process improvements, and equipment.
  • Participate as a technical representative on cross-functional project teams supporting internal initiatives and customer programs.
  • Serve as a technical interface with CDMO clients by supporting process development, technology transfer, and project execution activities.
  • Ensure all activities are conducted in compliance with cGMP requirements, company procedures, and applicable regulatory standards.
Job Requirements and Qualifications
  • Bachelor’s degree in chemical engineering or related engineering disciple.
  • Minimum of 3 years of relevant industrial experience, 5+ years of process development experience in pharmaceutical, biotechnology or CDMO environments is preferred.
  • Hands-on experience with process design, process development, scale-up, technology transfer, and manufacturing equipment.
  • Strong knowledge of process engineering principles and engineering methods used in pharmaceutical or biotechnology manufacturing.
  • Experience in pharmaceutical manufacturing, biologics, or related research and development environments is preferred.
  • Excellent analytical, problem-solving, technical writing, and communication skills.
  • Ability to work effectively in cross-functional teams and manage multiple priorities in a fast-paced manufacturing environment.
Why join SPL?
  • Perks include: competitive compensation; excellent benefits package - including Medical, Dental and Vision on Day 1; Life and AD&D Insurance, and Short and Long-term Disability; Health and Flexible Saving Account options; Employee Assistance Program, generous vacation; paid Holidays; 401k; advancement opportunities; team-oriented environment; community involvement; company events and more!

SPL is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, color, creed, disability, gender identity, national origin, protected veteran status, race, religion, sex, sexual orientation, and any other status protected by applicable local, state or federal law. Qualifications

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