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Protein Design Jobs in Ohio (NOW HIRING)

Cargill

Process Engineer- Akron, Ohio

Akron, OH

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Understanding of PI (data historian), ACAD (auto CAD), MS Project Equal Opportunity Employer ...

Cargill

Project Engineer

Sidney, OH

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Help manufacturing plant and facilities engineers with facility planning and design. * Help conduct ...

Cargill

Process Engineer- Akron, Ohio

Akron, OH · On-site

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Understanding of PI (data historian), ACAD (auto CAD), MS Project Equal Opportunity Employer ...

Cargill

Project Engineer

Sidney, OH · On-site

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Help manufacturing plant and facilities engineers with facility planning and design. * Help conduct ...

Ohio State University

Post Doctoral Scholar

Columbus, OH · On-site

$62K - $65K/yr

Requirement Doctoral Degree in Biophysics, Chemistry, Biochemistry, or a related field with specialization in structural biology and ligand design. Strong experience in protein modeling using ...

Cargill

Process Engineer- Akron, Ohio

Akron, OH · On-site

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Understanding of PI (data historian), ACAD (auto CAD), MS Project Equal Opportunity Employer ...

Howard

Research Scientist

Chauncey, OH · On-site

$50K - $60K/yr

... the design of polymeric nanoparticles for the delivery of bioactive agents Drug-loaded ... protein analysis), LC/MS, Flow cytometry, scanning electron microscopy, transmission electron ...

Cargill

Project Engineer

Sidney, OH

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Help manufacturing plant and facilities engineers with facility planning and design. * Help conduct ...

Cargill

Process Engineer- Akron, Ohio

Akron, OH · On-site

Our portfolio includes poultry, beef, egg, alternative protein, salt, oils, starches, sweeteners ... Understanding of PI (data historian), ACAD (auto CAD), MS Project Equal Opportunity Employer ...

Ohio State University

Postdoc Fellow

Columbus, OH · On-site

$47K - $64K/yr

... design forviral diseasesand other diseases that affect both humans and animals. The successful ... Strong background in molecular biology, protein biochemistry, andothercharacterization methods.

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Protein Design information

What is protein design?

Protein design is the process of creating new proteins or modifying existing ones to have specific functions or properties. This can involve using computational tools, laboratory techniques, or a combination of both to predict and engineer amino acid sequences that will fold into desired three-dimensional structures. Protein design is used in various fields, including medicine, biotechnology, and research, to develop novel enzymes, therapeutics, or materials. The field requires a strong understanding of biology, chemistry, and computer science to achieve successful outcomes.

What are the key skills and qualifications needed to thrive as a protein design scientist, and why are they important?

To thrive as a Protein Design Scientist, you need a strong background in molecular biology, biochemistry, and computational modeling, typically supported by an advanced degree in a relevant field. Proficiency with tools such as Rosetta, PyMOL, and molecular dynamics simulation software, as well as experience with protein expression and purification techniques, is essential. Analytical thinking, problem-solving, and effective communication are important soft skills to drive innovation and collaborate with interdisciplinary teams. These skills are crucial for designing functional proteins, troubleshooting experiments, and advancing research goals in biotechnology and pharmaceutical development.

What are some typical challenges faced by professionals in protein design, and how are they addressed within a team setting?

Professionals in protein design often encounter challenges such as predicting accurate protein folding, ensuring stability, and achieving desired biological activity. These complexities are typically addressed through close collaboration with computational biologists, structural biologists, and experimental scientists. Teams frequently hold cross-functional meetings to troubleshoot issues, share findings, and iterate on design strategies based on laboratory results. This collaborative environment helps leverage diverse expertise and accelerates the development of novel proteins with desired functions.

What is the difference between Protein Design vs Protein Engineering?

AspectProtein DesignProtein Engineering
Required CredentialsBiochemistry, Molecular Biology, BioinformaticsBiochemistry, Molecular Biology, Bioinformatics
Work EnvironmentResearch labs, biotech companies, academiaResearch labs, biotech companies, academia
Industry UsageDesigning novel proteins, drug development, synthetic biologyModifying existing proteins for improved function or stability

Protein Design focuses on creating new proteins with specific functions, often using computational methods. Protein Engineering involves modifying existing proteins to enhance or alter their properties. Both roles require similar skills and are used in research, biotech, and pharmaceutical industries, but their goals differ: one designs from scratch, the other optimizes existing proteins.

What are popular job titles related to Protein Design jobs in Ohio?

For Protein Design jobs in Ohio, the most frequently searched job titles are:

What job categories do people searching Protein Design jobs in Ohio look for?

The top searched job categories for Protein Design jobs in Ohio are:

What cities in Ohio are hiring for Protein Design jobs?

Cities in Ohio with the most Protein Design job openings:

Protein Design jobs near you
Infographic showing various Protein Design job openings in Ohio as of August 2026, with employment types broken down into 91% Full Time, 6% Part Time, and 3% Contract. Highlights an 82% Physical, 5% Hybrid, and 13% Remote job distribution.

Postdoctoral Fellow in Structural Biology and Enzyme Dynamics, College of Arts and Sciences

University of Cincinnati

Cincinnati, OH

$47K - $63K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 2 days ago

University Of Cincinnati rating

7.4

Company rating: 7.4 out of 10

Based on 42 frontline employees who took The Breakroom Quiz

339th of 631 rated colleges and universities

Job description

Current UC employees must apply internally via SuccessFactors 

Next Lives at the University of Cincinnati

Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to more than 53,600 students, 12,000 faculty and staff, and over 360,000 living alumni, UC, a Carnegie 1 institution, combines research prowess with a physical setting The New York Times has called “the most ambitious campus design program in the country." UC's momentum has never been stronger as the anchor of the Cincinnati Innovation District, the oldest cooperative education (co-op) program in the country with students earning $94 million annually through paid experiences, an academic health system, and as a member of the Big 12 Conference. The university contributes $10.6 billion in economic impact to the city and $22.7 billion to the state of Ohio. At UC, next is all of us. Learn more at uc.edu. 

UC is a mission-driven organization where we are committed to student success and positively transforming the community through scholarship and service.  We thrive on innovation, making an impact, and fostering an environment where staff and faculty are key contributors to UC’s success. 

Job Overview

The McLeod Lab (www.mcleodlab.com) at the University of Cincinnati in the Department of Chemistry is seeking a highly motivated postdoctoral fellow to investigate enzyme structure, function, and dynamics using advanced structural biology techniques. Our lab focuses on understanding protein conformational landscapes and enzymatic mechanisms through integrative biophysical approaches.

In particular, a successful applicant will be using cutting-edge approaches unique to the McLeod lab, including multi-temperature (doi: 10.1016/j.str.2025.02.013) & time-resolved crystallography (MMQX; doi: 10.1107/S205225252500288X) on new enzyme systems. The overall goal is to characterize non-model systems using new methodological approaches, with emphasis on describing the temperature dependence of enzyme activity. This unique and highly marketable training will likely help candidates differentiate themselves from peers.

In addition to gaining experience in multi-temperature and time-resolved crystallography, applicants will have the opportunity to learn and use small-angle X-ray scattering, cryo-electron microscopy, and enzyme kinetics.

The applicant will be responsible for experimental design, structural data collection and analysis, and collaboration with interdisciplinary teams. X-ray scattering and diffraction experiments will be conducted remotely and/or on-site at national synchrotron facilities (for ex. Advanced Photon Source & Cornell High-Energy Synchrotron Source). Opportunities for 

mentoring students, grant & scholarship/fellowship writing, independent project development, manuscript preparation, conference presentations, and some classroom teaching will be available.

The University of Cincinnati provides state-of-the-art research facilities, including:

  • A dedicated cryo-EM core facility featuring:
    • Thermo Talos L120C (120 kV TEM)
    • Thermo Glacios (200 kV TEM) with Falcon 4i detector
    • Vitrobot Mark IV for plunge freezing
  • Centralized high-performance computing
  • Custom time-resolved crystallography instrumentation
  • CaryUV-VIS 3500 multicell spectrophotometer
  • BioRad NGC fPLC
  • Formulatrix NT8 crystal setting robot
  • Other equipment and core facilities include: qPCR, SDS-PAGE, ITC, CD spectrometer, NMR/Mass spectroscopy core facilities

NOTE: Sponsorship for H-1 B visas is not available at this time.

Essential Functions
  • Independently conduct research experiments with rigor
  • Interpret data from biophysical and structural experiments
  • Familiarize yourself with relevant literature to develop novel ideas for new research directions for both the lab and your future independent career
  • Lead the production of manuscripts and presentations for which you will be the first author. Support the production of manuscripts, presentations, and reports for which you will be an author.
  • Mentor undergraduate and graduate students in scientific methodology, presentations, & writing.
  • Help maintain lab equipment and safety protocols
Required Education

Doctoral Degree in the appropriate field or discipline, or the recognized terminal degree

Required Experience
  • In-depth knowledge of specialized field, process or discipline.
  • May require experience with specialized software programs. 
Additional Qualifications Considered
  • Ph.D. in Structural Biology, Biochemistry, Biophysics, or a related field
  • Extensive experience in protein expression and purification (E. coli)
  • Extensive experience with at least X-ray crystallography or cryo-electron microscopy including sample preparation, data collection, and processing.
  • Excellent problem-solving skills and ability to work independently
  • Experience preparing manuscripts for peer review
Application Process

Interested candidates should submit the following to mcleodmw@ucmail.uc.edu:

  1. A cover letter detailing research interests and relevant experience
  2. A curriculum vitae
  3. Contact information for three references

Review of applications will begin immediately and continue until the position is filled.

The expected start date is September 2026, but it is flexible.

Physical Requirements/Work Environment
  • Office environment/no specific unusual physical or environmental demands.

Compensation and Benefits

UC offers an exceptional benefits package designed to support your well-being, financial security, and work-life balance. (UC Benefits) Eligibility may vary by position and FTE status. Highlights include:

Salary/Hourly Pay Rate Information: 56,697

Comprehensive Tuition Remission

UC provides tuition remission for you and your eligible dependents, covering tuition costs for nearly all undergraduate and graduate programs offered by the university.

Robust Retirement Plans

As a UC employee, you won’t contribute to Social Security (except Medicare). Instead, you’ll choose between state pension plans (OPERS, STRS) or an Alternative Retirement Plan (ARP), with UC contributing 14–18% of your salary based on position.

Real Work-Life Balance

UC prioritizes work-life balance with a generous time-off policy, including:

Vacation and sick time

11 paid holidays and additional end-of-year paid time off (Winter Season Days)

6 weeks of paid parental leave for new parents

Additional Benefits Include:

  • Competitive salary of $56,697 based on qualifications and experience
  • Comprehensive health coverage (medical, dental, vision, prescription)
  • Flexible spending accounts & wellness programs
  • Professional development & mentorship opportunities

To learn more about why UC is a great place to work, please visit our Careers Page.

UC is an E-Verify employer.  If hired into this position, you will be required to provide satisfactory proof of employment eligibility by providing acceptable, original forms of identification for employment verification via the Federal I-9 employment verification process. Click here for a list of acceptable documents.  

Important: To apply you must create a profile and submit a complete job application through the UC applicant portal. We are unable to consider “easy apply” applications submitted via other websites. For questions about the UC recruiting process or to request accommodations with the application, please contact UC HR at jobs@uc.edu.

Equal Opportunity Employer.  Building a workplace where all qualified applicants will receive consideration for employment, including Individuals with Disabilities and Protected Veterans.

REQ: 102134

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