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Protein Design Jobs in Ohio (NOW HIRING)

Ohio State University

Post Doctoral Scholar

Columbus, OH · On-site

$62K/yr

Responsibilities include molecular cloning, protein purification and biochemical characterization ... design principles of biological timekeeping. The successful candidate will play a leading role in ...

Varsity Tutors

Biochemistry Tutor

Cincinnati, OH · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Varsity Tutors

Biochemistry Tutor

Columbus, OH · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Varsity Tutors

Biochemistry Tutor

Akron, OH · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

Varsity Tutors

Biochemistry Tutor

Cleveland, OH · Remote

$18 - $40/hr

... protein purification strategies, and interpreting gel electrophoresis results. Emphasizes molecular-level reasoning and connects biochemistry to drug design, clinical diagnostics, and genetic disease ...

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Protein Design information

What is protein design?

Protein design is the process of creating new proteins or modifying existing ones to have specific functions or properties. This can involve using computational tools, laboratory techniques, or a combination of both to predict and engineer amino acid sequences that will fold into desired three-dimensional structures. Protein design is used in various fields, including medicine, biotechnology, and research, to develop novel enzymes, therapeutics, or materials. The field requires a strong understanding of biology, chemistry, and computer science to achieve successful outcomes.

What are the key skills and qualifications needed to thrive as a protein design scientist, and why are they important?

To thrive as a Protein Design Scientist, you need a strong background in molecular biology, biochemistry, and computational modeling, typically supported by an advanced degree in a relevant field. Proficiency with tools such as Rosetta, PyMOL, and molecular dynamics simulation software, as well as experience with protein expression and purification techniques, is essential. Analytical thinking, problem-solving, and effective communication are important soft skills to drive innovation and collaborate with interdisciplinary teams. These skills are crucial for designing functional proteins, troubleshooting experiments, and advancing research goals in biotechnology and pharmaceutical development.

What are some typical challenges faced by professionals in protein design, and how are they addressed within a team setting?

Professionals in protein design often encounter challenges such as predicting accurate protein folding, ensuring stability, and achieving desired biological activity. These complexities are typically addressed through close collaboration with computational biologists, structural biologists, and experimental scientists. Teams frequently hold cross-functional meetings to troubleshoot issues, share findings, and iterate on design strategies based on laboratory results. This collaborative environment helps leverage diverse expertise and accelerates the development of novel proteins with desired functions.

What is the difference between Protein Design vs Protein Engineering?

AspectProtein DesignProtein Engineering
Required CredentialsBiochemistry, Molecular Biology, BioinformaticsBiochemistry, Molecular Biology, Bioinformatics
Work EnvironmentResearch labs, biotech companies, academiaResearch labs, biotech companies, academia
Industry UsageDesigning novel proteins, drug development, synthetic biologyModifying existing proteins for improved function or stability

Protein Design focuses on creating new proteins with specific functions, often using computational methods. Protein Engineering involves modifying existing proteins to enhance or alter their properties. Both roles require similar skills and are used in research, biotech, and pharmaceutical industries, but their goals differ: one designs from scratch, the other optimizes existing proteins.

What are popular job titles related to Protein Design jobs in Ohio?

For Protein Design jobs in Ohio, the most frequently searched job titles are:

What job categories do people searching Protein Design jobs in Ohio look for?

The top searched job categories for Protein Design jobs in Ohio are:

What cities in Ohio are hiring for Protein Design jobs?

Cities in Ohio with the most Protein Design job openings:

Protein Design jobs near you
Infographic showing various Protein Design job openings in Ohio as of August 2026, with employment types broken down into 91% Full Time, 6% Part Time, and 3% Contract. Highlights an 82% Physical, 5% Hybrid, and 13% Remote job distribution.

Postdoctoral Scholar

Case Western Reserve University

Cleveland, OH • On-site

$55K - $62K/yr

Full-time

Medical, Life

Re-posted 17 days ago

Case Western Reserve University rating

8.3

Company rating: 8.3 out of 10

Based on 24 frontline employees who took The Breakroom Quiz

127th of 631 rated colleges and universities

Job description

Description
The successful candidate will participate in DOD-funded research projects focused on elucidating the molecular mechanisms of metabolic dysregulation in neurodegenerative diseases and developing potential therapeutics. The lab employs an integrated experimental approach, including in vitro cell culture systems, in vivo transgenic animal models, and patient-derived iPSC neurons and glial cells, to investigate disease pathogenesis. In parallel, the laboratory pursues therapeutic development, using rationally designed peptide inhibitors of protein-protein interactions and high-throughput screening strategies to identify nvel treatment approaches for neurological disorders. Other responsibilities include:
  • Design, execute, and analyze experiments in models of neurodegenerative disease
  • Perform and optimize molecular, biochemical, and cell-based assays, including work with cell lines, primary cultures, and iPSC-derived neurons and glia.
  • Conduct in vivo studies using transgenic animal models, including tissue collection and downstream analyses, as appropriate
  • Analyze and interpret experimental data, maintain detailed records, and prepare figures and reports.
  • Work on preparation of manuscripts for research findings
  • Collaborate with other lab members and interdisciplinary partners within and ouside the University
  • Particpate in the general scientific activities of the laboratory, inclduing mentoring junior trainees when appropriate

Qualifications
  • Doctorate in neuroscience, molecular biology, cell biology, pharmacology, or a related field
  • 4 years experience with cellular and molecular biology and animal models of disease
  • must be able to work in the United States

In compliance with the City of Cleveland's Pay Transparency Ordinance, the annual starting base salary for this position is $55,000-$62,652. CWRU considrs factors such as (but not limited o) the specific grant funding and the terms of the reseach grant when extending an offer. Postdocs receive individual and family healthcare benefits, life insurance, and employe assistance
Application Instructions
Interested parties should send a cover letter, CV, PhD certificate, and the names/phone numbers of three people who could provide letters of refernce by e-mail. https://apply.interfolio.com/183552

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