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Process Engineer Jobs in Fishers, IN (NOW HIRING)

INCOG

Senior Process Validation Engineer

Fishers, IN · On-site

$97K - $125K/yr

TSMS - Senior Process Validation Engineer The Senior Process Validation Engineer - Technical Services and Manufacturing Sciences (TSMS) will be responsible for leading all facets of Process ...

Eli Lilly and Company

Process Safety Lead

Indianapolis, IN · On-site

$98K - $128K/yr

The Engineering Technology Center (ETC) is a group of skilled engineering practitioners who possess deep technical expertise. The primary role of this position is to provide process safety related ...

Novartis

Process Expert - Comecer Lines

Indianapolis, IN · On-site

$84K - $126K/yr

Bachelor's degree in Engineering, Pharmacy, Pharmaceutical Technology, Chemistry or other science ... process, or to perform the essential functions of a position, please send an e-mail to us ...

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Process Engineer information

See Fishers, IN salary details

$46.3K

$86.1K

$133.4K

How much do process engineer jobs pay per year?

As of Jul 7, 2026, the average yearly pay for process engineer in Fishers, IN is $86,129.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,700.00 and $96,400.00 per year, depending on experience, location, and employer.

What engineers make $500,000 a year?

Highly experienced engineers in specialized fields such as petroleum engineering, aerospace engineering, or certain senior roles in software engineering can earn $500,000 or more annually, often including bonuses and stock options. These positions typically require advanced skills, extensive experience, and often involve leadership or executive responsibilities.

What are some common challenges Process Engineers face when implementing process improvements, and how can they overcome them?

Process Engineers often encounter challenges such as resistance to change from team members, integrating new technologies with existing systems, and ensuring process changes meet regulatory standards. Overcoming these obstacles typically involves clear communication, involving stakeholders early in the process, thorough documentation, and piloting changes before full-scale implementation. Building strong cross-functional relationships and continuously gathering feedback also help ensure that improvements are effective and sustainable.

What are Process Engineers?

Process Engineers are professionals who design, implement, and optimize industrial processes to improve efficiency, quality, and safety in manufacturing or production environments. They analyze workflows, troubleshoot process issues, and develop solutions to enhance productivity and reduce costs. Process Engineers often work in industries such as chemicals, pharmaceuticals, food and beverage, and energy, ensuring processes are compliant with environmental and safety regulations. Their work is vital for maintaining smooth operations and achieving organizational goals.

What are the key skills and qualifications needed to thrive as a Process Engineer, and why are they important?

To thrive as a Process Engineer, you need a solid background in chemical, mechanical, or industrial engineering, often supported by a relevant bachelor's degree and understanding of process optimization principles. Familiarity with process simulation software (such as Aspen Plus or AutoCAD), Six Sigma methodologies, and quality management systems is typically required. Strong analytical thinking, problem-solving abilities, and effective communication skills set candidates apart in this role. These skills and qualifications are essential to improve efficiency, ensure safety, and drive continuous improvement in industrial and manufacturing processes.

What is the role of a process engineer?

A process engineer designs, develops, and optimizes manufacturing processes to improve efficiency, quality, and safety. They analyze production data, troubleshoot issues, and implement process improvements using tools like Six Sigma and CAD software, often working in industrial or manufacturing environments. Certification such as a Professional Engineer (PE) license can enhance career prospects.

What is the difference between Process Engineer vs Manufacturing Engineer?

AspectProcess EngineerManufacturing Engineer
CredentialsBachelor's in Engineering, certifications like Six SigmaBachelor's in Engineering, certifications like Lean Manufacturing
Work EnvironmentDesigning and optimizing processes, R&D settingsOverseeing production lines, factory floors
Industry UsageManufacturing, chemical, aerospaceAutomotive, electronics, consumer goods

Process Engineers focus on designing and improving manufacturing processes, often working in R&D or engineering departments. Manufacturing Engineers concentrate on implementing and managing production on the factory floor. Both roles require similar technical skills and certifications but differ mainly in their scope and work environment.

What engineers make $200,000 a year?

Senior engineers in fields such as petroleum, software, aerospace, and chemical engineering often earn $200,000 or more annually, especially with extensive experience, advanced skills, and in high-demand industries. These roles typically require specialized knowledge, advanced degrees, and sometimes professional certifications like PE or PMP.

What Is a Process Engineer?

As a process engineer, often called a chemical engineer, you are responsible for creating efficient manufacturing processes in the manufacturing industry. You will evaluate current chemical processes and modify them as needed to ensure efficiency and profitability are maximized. You will also monitor processes for safety and environmental impact and seek to improve them whenever possible. Your responsibilities may vary depending on the particular industry in which you work and specialized skills sets may be required.

What do process engineers actually do?

Process engineers design, develop, and optimize manufacturing processes to improve efficiency, quality, and safety. They analyze production data, troubleshoot issues, and implement process improvements using tools like process flow diagrams and control systems, often working closely with production teams and utilizing industry standards. Their role ensures that manufacturing operations run smoothly and meet quality and safety standards.
More about Process Engineer jobs
What are the most commonly searched types of Process Engineer jobs in Fishers, IN? The most popular types of Process Engineer jobs in Fishers, IN are:
What cities near Fishers, IN are hiring for Process Engineer jobs? Cities near Fishers, IN with the most Process Engineer job openings:
Process Engineer jobs near you
Infographic showing various Process Engineer job openings in Fishers, IN as of July 2026, with employment types broken down into 80% Full Time, 5% Part Time, and 15% Contract. Highlights an 100% In-person job distribution, with an average salary of $86,129 per year, or $41.4 per hour.
Principal Process Engineer - API External Manufacturing (Large Molecule)

Principal Process Engineer - API External Manufacturing (Large Molecule)

Eli Lilly and Company

Indianapolis, IN • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 23 days ago

Eli Lilly and Company rating

8.8

Company rating: 8.8 out of 10

Based on 62 frontline employees who took The Breakroom Quiz

10th of 73 rated pharmaceutical

Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Position Brand Description:
The position of Principle Process Engineer - API EM Large Molecule reports to the API EM Engineering Director and provides technical leadership and expertise in conjunction with API EM contract manufacturer personnel in the reliable supply and commercialization of medicines with safety first and quality always by:
  • Developing and sustaining process knowledge in order to ensure the execution of the appropriate product, process, and operational control strategy at a number of Contract Manufacturers (CMs)
  • Assessment of the suitability of proposed equipment sets to ensure success of process validations
  • Direct and Indirect interaction with CM personnel to ensure reliable supply via the CM execution of the operational control strategy
  • FUME assessment to ensure an understanding of risk presented to the operational control strategy
  • Participation with internal or CM resources in the equipment specification, procurement, and IQ/OQ/PQ
  • Participation with internal and CM resources to assess the HSE and PSM elements of the CM that impact Lilly products
  • Engaged with internal and external resources in developing capabilities with new or evolving technologies that may impact delivery of internal or external portfolio assets.
  • Adherence to the expectations of the Lilly Red Book when carrying out interactions with API EM's CMs.

Key Objectives/Deliverables:
Coach and Mentor Process Team Members
  • Utilize past experiences with unit operation control to provide insight and feedback to members of the CM Joint Process Team (JPT).
  • Champion the application of statistical thinking and use of data to monitor process performance and make engineering decisions with CM members of the JPT.
  • Support and peer review root cause analysis around FUME and operational incidents.
  • Peer review documentation of learning points, technical studies, and incident investigations.

Scale-Up & Tech Transfer
  • Lead/support tech transfers and scale-up from development through PV and commercial supply.
  • Translate process intent into operating strategies, equipment fit/gap, batch documentation, and PV readiness at CMs.
  • Support engineering runs and PV readiness through parameter optimization and performance trending.

Develop and Sustain Process Knowledge
  • Identify process knowledge gaps that impact equipment and process capability.
  • Develop or support the capture of key process knowledge (examples include material and energy balances, kinetics, chemistry, process modeling, and equipment design basis).
  • Enable the development and maintenance of process knowledge. infrastructure such as key models, report history, lab models, and literature.
  • Utilize optimization resources and tools for process analysis and process improvement studies.
  • Review and track key process engineering metrics.

Provide Process & Equipment Support:
  • Identify systemic issues affecting production and reliable supply from CMs
  • Lead or participate in root cause analysis and countermeasure development and implementation for major safety, quality, or throughput incident investigations. Perform reviews of incident documentation for technical accuracy.
  • Review and approve documentation and engineering decisions.

Process Optimization & Continuous Improvement:
  • Support development and technical analysis for on-going continuous improvement activities.
  • Review and identify cost reduction opportunities, as well as process capacities and bottlenecks. Assist in prioritization of opportunities with respect to overall business objectives.
  • Work with the CMs to ensure the application of statistical thinking and methods to understand process variability and capability.
  • Perform and promote optimization of unit operation cycle time, loading, and yield performance.
  • Engage with late phase development and Engineering Technical Center resources to ensure staying contemporary with key engineering disciplines and developing portfolio platforms (e.g. continuous manufacturing operations).

Equipment Capability and Asset Management:
  • Create an appropriate methodology to ensure visibility of the ongoing state of qualification of key FUME systems at the CMs.
  • Review equipment and process system user requirements and qualification plans to ensure that the equipment and systems are appropriate for the intended purpose.
  • Act as customer representative for review of Contact Manufacturer (CM) requests for capital projects targeted at both short- and long-term needs.

Oversight of HSE and PSM:
  • Serve as the liaison for API EM and Global HSE on health, safety, and environmental (HSE) and process safety management (PSM) oversight at the relevant contract manufacturing sites.
  • Leverage internal Lilly experts in HSE and PSM to ensure appropriate risk reduction at CMs.
  • Participate in Lilly HSE and PSM audits of contract manufacturing sites as applicable.
  • Maintain key HSE and PSM metrics for review within API EM.

Adherence to Business, Quality, and Financial Systems:
  • Understand and follow all applicable Lilly policies and procedures with respect to interactions and oversight of API contract manufacturing sites.

Basic Requirements:
  • Bachelor of Science degree in Chemical Engineering, or another engineering discipline with 5 plus years experience in chemical manufacturing.
  • 3+ years of work experience in a manufacturing/process engineering related role related to large molecules.
  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Additional Preferences:
  • Experience in typical unit operations for Large Molecule API Manufacturing
  • Deep technical knowledge of API / Drug Substance manufacturing equipment and unit operations.
  • Demonstrated ability to apply fundamental chemical engineering principles to process understanding, problem solving, and process improvement.
  • Demonstrated ability to function in a team environment as a technical leader and as a member of teams.
  • Demonstrated ability to manage and prioritize competing priorities and to appropriately communicate verbally and in writing to various audiences.
  • Develop and implement innovative approaches to problems
  • Process Hazard Analysis experience
  • Successful application of root cause analysis and systematic problem solving
  • Strong Computer skills in a variety of software packages ( e.g Batch Plus, JMP, Visio, Aspen, Dynochem, OSI PI, MS Office Suite).
  • Visualize an operation/process and reflect it in a model.

Other Information:
  • This role is located onsite in Indianapolis, IN with the ability to work from home up to 4 days per month. Relocation assistance will be provided if applicable.
  • This role is not approved for 100% remote work
  • Travel may routinely be required to support process start-ups, troubleshooting, and commercial manufacturing. This travel is typically in the range of 15% to 25% annually, depending on the needs of the process(s).

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$66,000 - $171,600
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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About Eli Lilly

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Eli Lilly, based in Indianapolis, IN, US, is one of the pioneers in the pharmaceutical industry with a rich history dating back to 1876. This global pharmaceutical company focuses on discovering, developing, manufacturing and selling pharmaceutical products in approximately 120 countries. The company's product categories include endocrinology, oncology, cardiovascular, neuroscience, and immunology. Having invested over $9 billion in research and development in the past decade, Eli Lilly is also committed to creating high-quality medicines that meet real needs. As a recipient of several awards and recognitions, Eli Lilly is known for its focus on life-saving research and drug development. Their mission is to make medicines that help people live longer, healthier, and more active lives.

Industry

Pharmaceutical product wholesalers

Company size

10,000+ Employees

Headquarters location

Indianapolis, IN, US

Year founded

1876

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