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Principal Scientist Assay Development Jobs in Michigan

Merck

The Senior Director (Sr. Principal Scientist) has primary responsibility for the strategic planning ... Providing clinical development support of business development assessments of external ...

WuXi AppTec

$84K - $115K/yr

... outcomes for assays/studies/projects in the field of drug discovery and development ... Function as a study director, principal investigator, or project manager including serving as a ...

AleloPharma INC.

Research Scientist

Detroit, MI · On-site

The successful candidate will be responsible for assisting with small scale development and ... assays. The quality control will be conducted by RT-qPCR experiments using ultra-pure chimeric ...

AleloPharma INC.

Research Scientist

Detroit, MI · On-site

The successful candidate will be responsible for assisting with small scale development and ... assays. The quality control will be conducted by RT-qPCR experiments using ultra-pure chimeric ...

Van Andel Institute

Research Data Technician

Grand Rapids, MI · On-site

$17.25 - $23.75/hr

... computer science or a related field; Masters degree preferred. * Experience in the development and optimization of data analysis pipelines for assays, in production or research environments.

Clarkston Consulting

LIMS Consultant

Detroit, MI · On-site +1

... assay development, plate results, sample management, stability, and analytical testing processes * Design, configure, and validate assay workflows within, ensuring alignment with scientific ...

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Principal Scientist Assay Development information

What does a principal scientist assay development do?

A Principal Scientist in Assay Development leads the design, optimization, and validation of assays used for research, diagnostics, or drug development. They oversee laboratory teams, develop protocols, and ensure that assays meet regulatory and quality standards. Their role also involves troubleshooting complex scientific problems, collaborating with cross-functional teams, and staying current with technological advances in assay technologies. Principal Scientists play a key role in translating scientific concepts into reliable, reproducible assays that support broader organizational goals.

What are some common challenges faced by principal scientists assay development, and how can they be addressed?

Principal Scientists in Assay Development often encounter challenges such as optimizing assay sensitivity and specificity, troubleshooting inconsistent results, and scaling up assays for high-throughput screening. Addressing these issues requires strong analytical thinking, effective cross-functional collaboration with research, engineering, and quality assurance teams, and staying updated with the latest technological advances. Regularly reviewing validation protocols and actively participating in peer discussions can also help in overcoming technical hurdles and ensuring robust assay performance.

What are the key skills and qualifications needed to thrive as a principal scientist assay development, and why are they important?

To thrive as a Principal Scientist Assay Development, you need advanced expertise in biochemistry or molecular biology, a PhD or equivalent experience, and a strong background in assay design and validation. Familiarity with laboratory automation, data analysis software, and regulatory compliance systems such as GLP/GMP is typically required. Leadership, project management, and effective communication are crucial soft skills for guiding teams and collaborating across departments. These skills ensure robust assay performance, regulatory adherence, and efficient innovation in complex scientific environments.

What is the difference between Principal Scientist Assay Development vs Senior Scientist Assay Development?

AspectPrincipal Scientist Assay DevelopmentSenior Scientist Assay Development
CredentialsAdvanced degree (PhD or equivalent), extensive experienceMaster's or PhD, significant industry experience
Work EnvironmentLeads assay development projects, strategic planningExecutes assay development tasks, supports project teams
Employer & Industry UsagePharmaceutical, biotech, CROs, biotech companiesPharmaceutical, biotech, research labs

The main difference between Principal Scientist Assay Development and Senior Scientist Assay Development lies in their level of responsibility and leadership. Principal Scientists typically lead projects, set strategies, and have more extensive experience, while Senior Scientists focus on executing assays and supporting project goals. Both roles require strong technical expertise, but the Principal Scientist position involves higher-level decision-making and oversight.

What are popular job titles related to Principal Scientist Assay Development jobs in Michigan?

For Principal Scientist Assay Development jobs in Michigan, the most frequently searched job titles are:

What job categories do people searching Principal Scientist Assay Development jobs in Michigan look for?

The top searched job categories for Principal Scientist Assay Development jobs in Michigan are:

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Cities in Michigan with the most Principal Scientist Assay Development job openings:

Principal Scientist Assay Development jobs near you
Infographic showing various Principal Scientist Assay Development job openings in Michigan as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 14% Part Time, 3% Contract, and 1% Nights. Highlights an 90% Physical, 4% Hybrid, and 6% Remote job distribution.

Sr. Principal Scientist - R&D

Toyota Motor Sales, U.S.A., Inc.

Ann Arbor, MI • On-site

Full-time

Medical, Retirement, PTO

Re-posted 19 days ago

Toyota rating

7.1

Company rating: 7.1 out of 10

Based on 878 frontline employees who took The Breakroom Quiz

30th of 45 rated automakers

Job description

Overview
Who we are
Collaborative. Respectful. A place to dream and do. These are just a few words that describe what life is like at Toyota. As one of the world's most admired brands, Toyota is growing and leading the future of mobility through innovative, high-quality solutions designed to enhance lives and delight those we serve. We're looking for talented team members who want to Dream. Do. Grow. with us.
Toyota does not offer support or sponsorship of job applicants for employment-based visas or any other work authorization for this role now or in the future. You must have the right to work in the United States and not require Toyota support or sponsorship for immigration-related employment (e.g., H-1B, O-1, E-3, H-1B1, TN, F-1 OPT, F-1 STEM OPT, F-1 CPT, TN, (job flexibility benefits) (also known as I-140 or Adjustment of Status portability), etc.) now or in the future. You should not apply for this role if you will require Toyota to assist with immigration support or sponsorship now or in the future.
Who we're looking for
The Research Strategic Office (RSO) of Toyota Research Institute of North America (TRINA) is seeking a highly experienced and strategic leader to serve as the Senior Program Manager for Research Strategy & Portfolio Management.
This position is responsible for leading TRINA's research strategy, portfolio governance, and strategic partnership initiatives that directly influence long-term research investments, organizational priorities, and Toyota's global innovation strategy.
Working directly with research leadership, executive stakeholders, and external partners, this role evaluates emerging opportunities, optimizes research investments, and strengthens TRINA's position within the global research ecosystem. The role serves as a strategic advisor to TRINA leadership and operates with a high degree of autonomy in developing recommendations that influence enterprise research direction, resource allocation, and partnership priorities.
What you'll be doing
  • Lead the development and continuous improvement of portfolio governance frameworks that guide research prioritization, investment decisions, and resource allocation across TRINA.
  • Analyze research investments, outcomes, and emerging opportunities to ensure alignment with Toyota global strategy and long-term innovation objectives.
  • Advise senior leadership on research prioritization, resource allocation, and strategic investment decisions.
  • Lead strategic planning activities that connect research initiatives to future business opportunities and technology roadmaps.
  • Coordinate strategic research initiatives across TRINA and Toyota global research organizations.
  • Develop and maintain relationships with leading universities, national laboratories, industry partners, government agencies, and research consortia.
  • Representing TRINA with executive leaders in external strategic collaborations.
  • Prepare executive-level business cases, analyses, presentations, and recommendations.
  • Provide strategic insights on AI, advanced technology, and research ecosystems.
  • Influence organizational decisions through strategic analyses, executive communications, and cross-functional leadership.

This position will be located in Ann Arbor, Michigan.
What you bring
  • Must have a PhD in Engineering, Computer Science, Data Science, Physical Sciences, Business Strategy, Public Policy, or other related technical discipline.
  • Minimum of 15+ years of progressive leadership experience spanning research strategy, innovation management, technology planning, and strategic partnerships.
  • Strong record of influencing executive decision-making and shaping enterprise-level priorities.
  • Experience or an understanding of research funding Ecosystems and University Collaboration Models.
  • Track record of leading complex, cross-functional initiatives to successful outcomes.
  • Exceptional analytical, communication, stakeholder management, and executive presentation skills.
  • This role follows our return to office policy, work schedule, requiring onsite attendance Monday through Thursday. Remote work on Fridays may be permitted based on project priorities and business requirements; however, employees should be prepared for periodic mandatory onsite Fridays as needed.
  • Must be willing to travel up to 10%-20% domestically and internationally and maintain scheduling flexibility to participate in early and or late-evening meetings with stakeholders as business needs require.

Added bonus if you have
  • Experience leading or supporting advanced research organizations and innovation portfolios.
  • Experience or working knowledge of AI, technology forecasting, benchmarking, and innovation intelligence.
  • Experience in global, matrixed organizations.

What we'll bring
During your interview process, our team will provide you with all the details of our industry-leading benefits and career development opportunities. A few highlights include:
  • A work environment built on teamwork, flexibility, and respect
  • Professional growth and development programs to help advance your career, as well as tuition reimbursement
  • Team Member Vehicle Purchase Discount
  • Toyota Team Member Lease Vehicle Program (if applicable)
  • Comprehensive health care and wellness plans for your entire family
  • Toyota 401(k) Savings Plan featuring a company match, as well as an annual retirement contribution from Toyota regardless of whether you contribute
  • Paid holidays and paid time off
  • Referral services related to prenatal services, adoption, childcare, schools and more
  • Tax Advantaged Accounts (Health Savings Account, Health Care FSA, Dependent Care FSA)
  • Relocation (if applicable)

Belonging at Toyota
Our success begins and ends with our people. We embrace all perspectives and value unique human experiences. Respect for all is our North Star. Toyota is proud to have 10+ different Business Partnering Groups across 100 different North American chapter locations that support team members' efforts to dream, do and grow without questioning that they belong.
Applicants for our positions are considered without regard to race, ethnicity, national origin, sex, sexual orientation, gender identity or expression, age, disability, religion, military or veteran status, or any other characteristics protected by law.
Have a question, need assistance with your application or do you require any special accommodations? Please send an email to talent.acquisition@toyota.com.

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