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Principal Scientist Assay Development Jobs in Michigan

Corium Innovations

R&D Principal Scientist

Grand Rapids, MI · On-site

$140 - $200/hr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Due to our continued growth, Corium Innovations is seeking an R&D Principal Scientist who will lead a highly motivated team through method development, qualification and optimization supporting ...

Corium Innovations

R&D Principal Scientist

Grand Rapids, MI

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

D Principal Scientist who will lead a highly motivated team through method development, qualification and optimization supporting existing and future drug products. This position requires method ...

Toyota

Sr. Principal Scientist - R&D

Ann Arbor, MI · On-site +1

  • Medical

  • Retirement

  • PTO

Lead the development and continuous improvement of portfolio governance frameworks that guide ... Must have a PhD in Engineering, Computer Science, Data Science, Physical Sciences, Business ...

Merck & Co.

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Our R&D Laboratories are a true scientific research facility of tomorrow and will take our leading discovery capabilities and world-class small molecule and biologics R&D expertise to create ...

New

AleloPharma INC.

Research Scientist

Detroit, MI · On-site

The successful candidate will be responsible for assisting with small scale development and ... assays. The quality control will be conducted by RT-qPCR experiments using ultra-pure chimeric ...

AleloPharma INC.

Research Scientist

Detroit, MI · On-site

The successful candidate will be responsible for assisting with small scale development and ... assays. The quality control will be conducted by RT-qPCR experiments using ultra-pure chimeric ...

Td

Principal Data Scientist (US)

Southfield, MI

$148K - $223K/yr

Growth opportunities and skill development are defining features of the colleague experience at TD ... In addition, the Principal Data Scientist provides technical expertise with a focus on bank and ...

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Principal Scientist Assay Development information

What are the key skills and qualifications needed to thrive as a principal scientist assay development, and why are they important?

To thrive as a Principal Scientist Assay Development, you need advanced expertise in biochemistry or molecular biology, a PhD or equivalent experience, and a strong background in assay design and validation. Familiarity with laboratory automation, data analysis software, and regulatory compliance systems such as GLP/GMP is typically required. Leadership, project management, and effective communication are crucial soft skills for guiding teams and collaborating across departments. These skills ensure robust assay performance, regulatory adherence, and efficient innovation in complex scientific environments.

What is the difference between Principal Scientist Assay Development vs Senior Scientist Assay Development?

AspectPrincipal Scientist Assay DevelopmentSenior Scientist Assay Development
CredentialsAdvanced degree (PhD or equivalent), extensive experienceMaster's or PhD, significant industry experience
Work EnvironmentLeads assay development projects, strategic planningExecutes assay development tasks, supports project teams
Employer & Industry UsagePharmaceutical, biotech, CROs, biotech companiesPharmaceutical, biotech, research labs

The main difference between Principal Scientist Assay Development and Senior Scientist Assay Development lies in their level of responsibility and leadership. Principal Scientists typically lead projects, set strategies, and have more extensive experience, while Senior Scientists focus on executing assays and supporting project goals. Both roles require strong technical expertise, but the Principal Scientist position involves higher-level decision-making and oversight.

What are some common challenges faced by principal scientists assay development, and how can they be addressed?

Principal Scientists in Assay Development often encounter challenges such as optimizing assay sensitivity and specificity, troubleshooting inconsistent results, and scaling up assays for high-throughput screening. Addressing these issues requires strong analytical thinking, effective cross-functional collaboration with research, engineering, and quality assurance teams, and staying updated with the latest technological advances. Regularly reviewing validation protocols and actively participating in peer discussions can also help in overcoming technical hurdles and ensuring robust assay performance.

What does a principal scientist assay development do?

A Principal Scientist in Assay Development leads the design, optimization, and validation of assays used for research, diagnostics, or drug development. They oversee laboratory teams, develop protocols, and ensure that assays meet regulatory and quality standards. Their role also involves troubleshooting complex scientific problems, collaborating with cross-functional teams, and staying current with technological advances in assay technologies. Principal Scientists play a key role in translating scientific concepts into reliable, reproducible assays that support broader organizational goals.

What are popular job titles related to Principal Scientist Assay Development jobs in Michigan?

For Principal Scientist Assay Development jobs in Michigan, the most frequently searched job titles are:

What job categories do people searching Principal Scientist Assay Development jobs in Michigan look for?

The top searched job categories for Principal Scientist Assay Development jobs in Michigan are:

What cities in Michigan are hiring for Principal Scientist Assay Development jobs?

Cities in Michigan with the most Principal Scientist Assay Development job openings:

Principal Scientist Assay Development jobs near you
Infographic showing various Principal Scientist Assay Development job openings in Michigan as of July 2026, with employment types broken down into 1% As Needed, 78% Full Time, 17% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution.

Principal Scientist, Biology

KMR Search Group

Ann Arbor, MI • On-site

Full-time

Re-posted 19 days ago

Job description


Bio-pharmaceutical company focused on the discovery and development of small-molecule immune modulators for the treatment of cancers, inflammation and autoimmune diseases, has an opening for a Principal Scientist at its Ann Arbor, Michigan site. The successful candidates will enjoy working in a fast paced, collaborative environment and be skilled at designing and conducting experiments, data presentation and leading/managing project teams to achieve goals.
Responsibilities
  • Independently design and execute experiments using cutting-edge technologies in the field of immunology and immuno-oncology to support drug discovery and elucidate mechanisms of action of key compounds
  • Lead research efforts to develop and implement novel assays for compound characterization, PK/PD and biomarker development
  • Interact closely with medicinal chemists to provide biology expertise and support as the biology lead of a drug discovery project team
  • Actively and openly participate in research discussions and reviews

Qualifications:
  • PhD in cell biology, molecular biology, immunology or a related field with 9+ years of biotech or pharmaceutical industry research experience in autoimmune, inflammation or immune-oncology therapeutic areas
  • Outstanding laboratory skills. Must have extensive research experience on immune cells and a proven track record of scientific success
  • Possess a high level of critical thinking, a can-do spirit, a strong desire to learn new areas and the ability to conduct independent research and lead multidisciplinary teams in a matrix environment
  • Excellent communication skills

Apply