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Principal Sas Programmer Jobs (NOW HIRING)

Cytel

Principal Biostatistician FSP

Dover, DE

An experienced Principal Biostatistician with a passion for clinical development and analysis ... SAS programming skills for QCing critical outputs, Efficacy/Safety tables, and working closely with ...

Cytel

Principal Biostatistician FSP

Hartford, CT

An experienced Principal Biostatistician with a passion for clinical development and analysis ... SAS programming skills for QCing critical outputs, Efficacy/Safety tables, and working closely with ...

Cytel

Principal Biostatistician FSP

Honolulu, HI · On-site

An experienced Principal Biostatistician with a passion for clinical development and analysis ... SAS programming skills for QCing critical outputs, Efficacy/Safety tables, and working closely with ...

AtriCure

Senior Principal Statistician

Mason, OH · On-site

$81K - $100K/yr

Knowledge of programming Tables, Listings and Figures in SAS for FDA submission * Good know of SAS, R and Sample size calculations software * Ability to work independently * Ability to travel 10% ...

Jobtailor

Principal Biostatistician

Cambridge, MA · On-site

Conversant with SAS programming and detailed knowledge of statistical software * Working knowledge of regulatory guidelines and needs for statistical analysis * Demonstrated leadership and ...

Zenius

Principal CICS Systems Programmer

Woodlawn, MD · On-site

Principal CICS Systems Programmer *** Selected candidate must be willing to work on-site in ... Utilize IBM MQ for z, SAS, REXX, SMP/E, z/OSMF, and CICSplex for system integrations and support as ...

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How much do principal sas programmer jobs pay per month?

As of Sep 13, 2026, the average monthly pay for principal sas programmer in the United States is $14,500.00, according to ZipRecruiter salary data. Most workers in this role earn between $12,291.67 and $15,416.67 per month, depending on experience, location, and employer.

What is a principal SAS programmer?

A Principal SAS Programmer is a senior-level professional responsible for leading statistical programming activities in clinical trials or other data-driven industries. They design, develop, validate, and maintain complex SAS programs to analyze and report data, ensuring compliance with regulatory guidelines. Additionally, they collaborate with biostatisticians, data managers, and clinical teams to support study objectives. Their role often includes mentoring junior programmers and optimizing programming workflows for efficiency and accuracy.

What are the typical responsibilities and day-to-day tasks for a principal SAS programmer?

As a Principal SAS Programmer, your daily tasks often include developing and validating statistical programs, overseeing the creation of datasets, tables, listings, and figures (TLFs) for clinical studies, and ensuring data quality and compliance with regulatory standards. You’ll collaborate with statisticians, data managers, and clinical teams to understand study requirements and deadlines. Additionally, you may mentor junior programmers, provide programming guidance, and help resolve technical challenges within the team. This role offers a mix of independent programming work and cross-departmental collaboration, making it both technically challenging and highly impactful within the organization.

What are the key skills and qualifications needed to thrive in the principal SAS programmer position, and why are they important?

To thrive as a Principal SAS Programmer, you need advanced expertise in SAS programming, statistical analysis, and clinical data management, often gained through a degree in statistics, computer science, or a related field. Familiarity with industry-standard tools like SAS Base, SAS Macro, and regulatory submission standards such as CDISC (SDTM, ADaM), as well as relevant certifications, is highly valued. Leadership, problem-solving, and effective communication are essential soft skills for managing projects and collaborating with cross-functional teams. These competencies are crucial for ensuring data integrity, regulatory compliance, and the successful delivery of complex clinical projects.

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Principal Sas Programmer jobs near you
Infographic showing various Principal Sas Programmer job openings in the United States as of September 2026, with employment types broken down into 89% Full Time, 9% Part Time, 1% Temporary, and 1% Contract. Highlights an 88% Physical, 4% Hybrid, and 8% Remote job distribution, with an average salary of $174,000 per year, or $83.7 per hour.

Principal Biostatistician FSP

Dover, DE

Cytel
See more jobs at Cytelexternal

Full-time

Posted 15 days ago

Job description

Who Are You?

An experienced Principal Biostatistician with a passion for clinical development and analysis, adept at utilizing advanced statistical methods, you will lead one Phase I-IV clinical studies across your region. You are excited and enthusiastic, motivate your teams to do great work and collaborate easily with your clients. You never settle for what is, but always push clinical development forward to what it could be. You motivate others to do the same.

Sponsor-dedicated:

Working fully embedded within one of our pharmaceutical clients, with the support of Cytel right behind you, you'll be at the heart of our client's innovation. As a Biostatistician you will be dedicated to one of our global pharmaceutical clients; a company that is driving the next generation of patient treatment, where individuals are empowered to work with autonomy and ownership. This is an exciting time to be a part of this new program.

Position Overview:

Our Principal Biostatisticians provide statistical and development support and influence for the associated client's trials providing expertise into processes, clinical development plans, concept sheets and protocols, as well as potentially providing oversight of work supported by other vendors. You will formulate integrated analytical approach to mine data sources, employ statistical methods, machine learning & deep learning algorithms to discover actionable insights and automate process for reducing effort and time for repeated use.

As a Principal Biostatistician, your responsibilities will include:

  • Lead statistical activities for assigned Clinical Trials (Phases 1 to 4) independently from protocol design to reporting of results.
  • Represent Statistics function on cross-functional trial (and possibly indication / project) teams and collaborate effectively with all cross-functional stakeholders.
  • Oversight of internal programming activities and/or CRO contributions on assigned clinical trials and other activities.
  • Contribute to or lead other activities from a statistical perspective as appropriate, including but not limited to Safety Reporting, ISS/ISE, addressing questions from Health Authorities, Publications.
  • Use SAS and/or R for purposes like QC of datasets and deliverables, inferential statistical analyses, modelling/simulation, exploratory analyses etc.
  • Contribute to and participate in other initiatives at Cytel or sponsor side as appropriate.
  • Oversight of more junior Statisticians as required.
  • Seeking an independent study level lead who
  • has a clear technical understanding of how to analyze clinical trial data properly (ICH E9 guideline)
  • experiences of representing biostats function to collaborate with stakeholders cross functionally
  • is equipped with strong communication skills
  • has a strong self-learning willingness to perform their own duties with minimum guidance.

Here at Cytel we want our employees to succeed and we enable this success through consistent training, development and support. To be successful in this position you will have:

  • Minimum of Bachelor's degree in statistics or a related discipline.
  • 9+ years supporting clinical trials in the Pharmaceutical or Biotechnology industry.
  • Ability to work independently, demonstrate initiative and flexibility through effective and innovative leadership.
  • Attention to detail and quality focused, excellent interpersonal and communication skills, innovative, and collaborative behaviours
  • SAS programming skills for QCing critical outputs, Efficacy/Safety tables, and working closely with Programmers.
  • Knowledge of R programming (R Shiny/Python).

Cytel Inc. is an Equal Employment / Affirmative Action Employer. Applicants are considered for all positions without regard to race, color, religion, sex, national origin, age, veteran status, disability, sexual orientation, gender identity or expression, or any other characteristics protected by law.

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