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Principal Sas Programmer Jobs (NOW HIRING)

Vrtx

Principal Statistical Programmer

Boston, MA · Remote

$149K - $223K/yr

The Principal Statistical Programmer works with management to delegate tasks appropriately, track ... Performs quality control checks of SAS code and output produced by other Statistical Programmers to ...

PSI CRO

Principal Statistician

Durham, NC · On-site +1

Conduct departmental induction course and project-specific training for statisticians and SAS programmers * Prepare for and attend internal and external study audits pertinent to Statistics

PSI CRO

Principal Statistician

Durham, NC · On-site

Conduct departmental induction course and project-specific training for statisticians and SAS programmers * Prepare for and attend internal and external study audits pertinent to Statistics

PSI CRO

Principal Statistician

Durham, NC · On-site

Conduct departmental induction course and project-specific training for statisticians and SAS programmers * Prepare for and attend internal and external study audits pertinent to Statistics

PSI CRO

Principal Statistician

Durham, NC

Conduct departmental induction course and project-specific training for statisticians and SAS programmers * Prepare for and attend internal and external study audits pertinent to Statistics

PSI CRO

Principal Statistician

Conduct departmental induction course and project-specific training for statisticians and SAS programmers * Prepare for and attend internal and external study audits pertinent to Statistics

SAS

Principal Simulation Architect

Principal Simulation Architect- Remote or Hybrid We're a leader in data and AI. Through our ... Application Large Team Lead - Experience leading a team of 15 or more developers * SAS ...

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How much do principal sas programmer jobs pay per month?

As of Jun 21, 2026, the average monthly pay for principal sas programmer in the United States is $14,500.00, according to ZipRecruiter salary data. Most workers in this role earn between $12,291.67 and $15,416.67 per month, depending on experience, location, and employer.

What are the typical responsibilities and day-to-day tasks for a Principal SAS Programmer?

As a Principal SAS Programmer, your daily tasks often include developing and validating statistical programs, overseeing the creation of datasets, tables, listings, and figures (TLFs) for clinical studies, and ensuring data quality and compliance with regulatory standards. You’ll collaborate with statisticians, data managers, and clinical teams to understand study requirements and deadlines. Additionally, you may mentor junior programmers, provide programming guidance, and help resolve technical challenges within the team. This role offers a mix of independent programming work and cross-departmental collaboration, making it both technically challenging and highly impactful within the organization.

What is a Principal SAS Programmer job?

A Principal SAS Programmer is a senior-level professional responsible for leading statistical programming activities in clinical trials or other data-driven industries. They design, develop, validate, and maintain complex SAS programs to analyze and report data, ensuring compliance with regulatory guidelines. Additionally, they collaborate with biostatisticians, data managers, and clinical teams to support study objectives. Their role often includes mentoring junior programmers and optimizing programming workflows for efficiency and accuracy.

Are SAS programmers in demand?

SAS programmers are in demand in industries such as healthcare, finance, and pharmaceuticals that rely on data analysis and reporting. Strong skills in SAS, along with knowledge of data management and statistical analysis, can improve job prospects, especially for those with certifications and experience in analytics environments.

What are the key skills and qualifications needed to thrive in the Principal Sas Programmer position, and why are they important?

To thrive as a Principal SAS Programmer, you need advanced expertise in SAS programming, statistical analysis, and clinical data management, often gained through a degree in statistics, computer science, or a related field. Familiarity with industry-standard tools like SAS Base, SAS Macro, and regulatory submission standards such as CDISC (SDTM, ADaM), as well as relevant certifications, is highly valued. Leadership, problem-solving, and effective communication are essential soft skills for managing projects and collaborating with cross-functional teams. These competencies are crucial for ensuring data integrity, regulatory compliance, and the successful delivery of complex clinical projects.

What is the average salary for a SAS programmer?

The average salary for a SAS programmer varies by experience and location but typically ranges from $70,000 to $110,000 annually. Senior SAS programmers with advanced skills and certifications can earn higher salaries, especially in industries like pharmaceuticals and finance where data analysis is critical.

How much do SAS programmers make?

SAS programmers typically earn between $70,000 and $120,000 annually, depending on experience, location, and industry. Senior roles or those with advanced skills in data analysis and programming may have higher salaries, especially in healthcare, finance, or pharmaceutical sectors.

What is the salary of principal statistical programmer in Eli Lilly?

The salary for a Principal Statistical Programmer at Eli Lilly typically ranges from $110,000 to $150,000 annually, depending on experience, location, and qualifications. This role often requires proficiency in SAS programming and knowledge of clinical trial data analysis.
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Principal Sas Programmer jobs near you
Infographic showing various Principal Sas Programmer job openings in the United States as of June 2026, with employment types broken down into 33% Full Time, and 67% Contract. Highlights an 100% In-person job distribution, with an average salary of $174,000 per year, or $83.7 per hour.
Principal Statistical Programmer

Principal Statistical Programmer

Vertex Pharmaceuticals

Boston, MA • On-site

$149K - $223K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 25 days ago

Job description

Job Description
General Summary:
The Principal Statistical Programmer works with management to delegate tasks appropriately, track progress, and provide expert technical support to team members. In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer.
Key Duties and Responsibilities:
  • Works regularly with advanced features of SAS (including interfacing ability with other software applications and operating system tools)
  • Performs quality control checks of SAS code and output produced by other Statistical Programmers to ensure accuracy and consistency within group
  • Demonstrates in-depth knowledge of clinical development and medical data
  • Solves complex clinical trial reporting problems and demonstrates technical proficiency and exercises judgment in supporting daily operations and ensuring that study tasks are completed accurately and in a timely manner
  • Engages with a variety of other functions, including Statistical Programmers, Biostatisticians, Data Management, and other departments engaged in providing data and submission-related activities, often at Senior Management levels
  • Creates all files, documents, and analyses necessary to support an electronic submission in eCTD format, including ISS/ISE
  • Provides leadership to ensure compliance with Vertex SOP'S and FDA/ICH/GCP regulations
  • Provides technical and project management skills to create, review, and approve documentation required to support data analysis, reporting, and CDlSC data submission
  • Participates in project management cross-functional teams that work on standard operating procedures, guidelines, process improvements, system validation and acquisition, customization, and integration of new tools and technologies

    • Knowledge and Skills:
  • Proficiency in all SAS language, procedures, and functions commonly used in clinical trial reporting including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH
  • Intermediate knowledge of CDISC Standards
  • Intermediate knowledge of clinical trials
  • Regulatory submission experiences
  • Effective communication (written and verbal) skills to explain difficult information

    • Education and Experience:
  • Bachelors degree in a Scientific Discipline
  • Typically requires 5+ for M.S. or above and 8+ years for B.S. years of work experience in Biotech, Pharmaceuticals or Clinical Research Organization

    • Pay Range:
    $149,200 - $223,800
    Disclosure Statement:
    The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
    At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
    Flex Designation:
    Remote-Eligible
    Flex Eligibility Status:
    In this Remote-Eligible role, you can choose to be designated as:
    1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
    2. Hybrid: work remotely up to two days per week; or select
    3. On-Site: work five days per week on-site with ad hoc flexibility.
    Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
    #LI-Remote
    Company Information
    Vertex is a global biotechnology company that invests in scientific innovation.
    Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
    Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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