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Principal Clinical Research Jobs (NOW HIRING)

Veristat

... research projects, including paper-based and electronic data capture (EDC) studies, and is responsible for overall data quality and documentation on clinical research projects. The Principal Clinical ...

IMA Clinical Research, Inc.

Principal Investigator (MD/DO) - Clinical Research | Part-Time/Full-Time | Albuquerque, NM IMA Clinical Research is seeking a board-certified MD or DO with a background in general medicine and/or ...

Emmes

Principal Clinical Data Manager

Rockville, MD · On-site

At Emmes Group , we're shaping the future of clinical research - where human intelligence meets ... The Principal Clinical Data Manager provides data management leadership and subject matter ...

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How much do principal clinical research jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for principal clinical research in the United States is $43.09, according to ZipRecruiter salary data. Most workers in this role earn between $36.54 and $43.03 per hour, depending on experience, location, and employer.

What is a principal clinical research?

A Principal Clinical Researcher is a senior professional responsible for designing, overseeing, and managing clinical research studies, often within the pharmaceutical, biotechnology, or medical device industries. They ensure that all clinical trials adhere to regulatory guidelines, ethical standards, and scientific protocols. These experts lead research teams, coordinate with stakeholders, analyze data, and contribute to the development of new medical treatments or therapies. Their leadership is critical to the success of clinical studies and advancing medical knowledge.

What are the key skills and qualifications needed to thrive as a principal clinical research professional?

To thrive as a Principal Clinical Research professional, you need deep expertise in clinical trial design, regulatory compliance, data analysis, and a relevant advanced degree (such as PhD, PharmD, or MD). Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like GCP (Good Clinical Practice) are typically required. Strong leadership, problem-solving abilities, and effective communication skills distinguish top performers in this role. These skills ensure studies are conducted ethically, efficiently, and in alignment with regulatory standards, ultimately advancing scientific and medical progress.

What are some common challenges faced by principal clinical research professionals in managing multicenter clinical trials?

Principal Clinical Research professionals often encounter challenges such as ensuring consistent protocol adherence across multiple study sites, managing large and diverse research teams, and coordinating communication among stakeholders. They must also navigate regulatory requirements that can vary by region and address data quality issues that arise from varying site performance. Effective leadership, strong organizational skills, and proactive problem-solving are essential for successfully managing these complex trials.

What is the difference between Principal Clinical Research vs Clinical Research Associate?

AspectPrincipal Clinical ResearchClinical Research Associate
Required CredentialsAdvanced degrees (e.g., MS, PhD), extensive experience, certifications like CCRPBachelor’s degree, clinical research training, certifications like CCRP or CCRA often preferred
Work EnvironmentLeadership role overseeing multiple studies, strategic planning, and team managementSite monitoring, data collection, ensuring protocol compliance at clinical sites
Employer & Industry UsagePharmaceutical companies, CROs, biotech firms, academic institutionsPharmaceutical companies, CROs, clinical trial sites

The Principal Clinical Research role involves strategic oversight, leadership, and extensive experience, whereas the Clinical Research Associate focuses on site monitoring and data collection. Both roles are essential in clinical trials, but they differ significantly in responsibilities and seniority.

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Principal Clinical Research jobs near you
Infographic showing various Principal Clinical Research job openings in the United States as of September 2026, with employment types broken down into 75% Full Time, and 25% Part Time. Highlights an 100% In-person job distribution, with an average salary of $89,619 per year, or $43.1 per hour.

Principal Clinical Data Manager

Remote

Veristat
Pharmaceutical and Medicine Manufacturing • 501 - 1,000 employees
Learn more about Veristatexternal

Full-time

Medical, Retirement

Posted 5 days ago

Job description

Job Description:

Principal Clinical Data Manager

Working independently and in consort with management, the Principal Clinical Data Manager is responsible for the performance of data management tasks from study start-up through database lock for assigned clinical research projects, including paper-based and electronic data capture (EDC) studies, and is responsible for overall data quality and documentation on clinical research projects.


The Principal Clinical Data Manager will work on mid-to-large complex projects in various indications, at times serving as program manager, overseeing multiple studies under the same client. S/he will lead a team of CDMs to ensure all the contracted activities are carried out according to the Standard Operating Procedures of Veristat and/or Sponsor specific requirements.

In consort with Data Management leadership, the Principal Clinical Data Manager promotes consistent operations, efficient use of resources, and sharing of knowledge and best practices.

S/he, in consultation with the managers, will assist with the training of other data managers on project specific and general data management processes, procedures and systems, as well as providing training to other functions across the company as needed.

Make an Impact at Veristat!

Join a global team with more than 30 years of expertise accelerating life-changing therapies to patients worldwide.

  • 105+ approved therapies for marketing applications prepared by Veristat
  • 480+ oncology projects in the past 5 years
  • 350+ rare disease projects delivered in the past 5 years
  • Flexible, inclusive culture - 70% remote workforce, 66% women-led teams
  • Learn more about our core values here!

What we offer:

The estimated hiring range for this role is $114K - 150K plus applicable bonus. This hiring range is specific to the USA and will vary for other regions based upon local market data. Final salary is ultimately decided upon taking into account a wide range of factors, including but not limited to: skills and experience, licensure and certifications, education, specific location and dynamic market data.

  • Benefits vary by location and may include:

    • Remote working

    • Flexible time off

    • Paid holidays

    • Medical insurance

    • Tuition reimbursement

    • Retirement plans

What we look for

  • Bachelor's degree in a related field & 7+ years of relevant experience; at least 5 years' experience in clinical data management experience in a clinical research setting and 4 years of experience in leading project teams, required.
  • Thorough knowledge of International Conference on Harmonisation (ICH) Good Clinical Practice (GCP) guidelines and other applicable regulatory rules and guidelines as well as of medical terminology, clinical trials, and clinical research.
  • Working knowledge of the relationship and regulatory obligation of the contract research organization (CRO) industry with pharmaceutical / biotech companies.
  • Demonstrated ability to lead by example, and demonstrated skill for technical leadership of staff.
  • Demonstrated ability to serve as a strong internal and external consultant, influence without authority, and guide project teams to mutually acceptable outcomes .
  • Demonstrated ability to operate with the "big picture" in mind and serve as a thought partner to management as needed.
  • Expert level skills in use of computer technology, including clinical trial databases and applications (e.g., IBM Clinical Development, Medidata RaveX), with a strong desire and ability to learn new applications.
  • Detailed understanding of project planning and management methods.
  • Excellent interpersonal, communication, and organizational skills with the ability to work independently and in a team environment.
  • Ability to work in different projects with different priorities and act as team mentor, and provide data management expertise.

Automated Decision Making: All applicants are reviewed by a member of the Veristat Talent Acquisition team; Veristat does not utilize an automated decision-making process.

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Veristat is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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