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Principal Clinical Data Manager Jobs (NOW HIRING)

Ocugen Inc

Senior Clinical Data Manager

Malvern, PA · On-site

Position Summary The Senior Clinical Data Manager plays a pivotal role within Ocugen's clinical ... principal level descriptions). * Provide mentorship and technical guidance to junior data ...

Worldwide Clinical Trials

Clinical Data Manager

Join us! Clinical Data Manager does at Worldwide Oversee, lead, manage, and provide technicalexpertisewithin the assigned projects to ensure that they are executed in an efficient,accurate ...

ProPharma Group

The Clinical Data Manager performs activities pertaining to the conduct of Phase I-III clinical trials in accordance with ICH/Good Clinical Practices (GCP) and other relevant procedures and ...

ProPharma Group

Clinical Data Manager

Charleston, WV · On-site +1

Clinical Data Manager The Clinical Data Manager performs activities pertaining to the conduct of Phase I-III clinical trials in accordance with ICH/Good Clinical Practices (GCP) and other relevant ...

Terumo Corporation

Clinical Data Manager

Somerset, NJ · On-site

Job Summary The Clinical Data Manager is responsible for supporting all data management activities for research studies in compliance with departmental SOPs and all regulatory guidelines. The ...

Medical Affairs

Clinical Data Manager

Somerset, NJ · On-site

Job Summary The Clinical Data Manager is responsible for supporting all data management activities for research studies in compliance with departmental SOPs and all regulatory guidelines. The ...

Abbott

MN · On-site

$45 - $47/hr

Clinical Data Manager Location: Maple Grove, MN Duration: 7 Months 100% Onsite Summary: The Clinical Data Manager is responsible for managing the development, documentation, and execution of risk ...

Abbott

Clinical Data Manager

Maple Grove, MN · On-site

$45 - $47/hr

Clinical Data Manager Location: Maple Grove, MN Duration: 7 Months 100% Onsite Summary: The Clinical Data Manager is responsible for managing the development, documentation, and execution of risk ...

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How much do principal clinical data manager jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for principal clinical data manager in the United States is $57.17, according to ZipRecruiter salary data. Most workers in this role earn between $45.19 and $68.03 per hour, depending on experience, location, and employer.

What does a principal clinical data manager do?

A Principal Clinical Data Manager oversees the collection, processing, and management of clinical trial data to ensure its accuracy, integrity, and compliance with regulatory standards. They lead data management teams, develop data management plans, and coordinate with other clinical project stakeholders. Their responsibilities also include reviewing data for consistency, resolving discrepancies, and ensuring that final databases are ready for statistical analysis and regulatory submission. Principal Clinical Data Managers play a key role in ensuring the quality and reliability of data used to evaluate new medical treatments.

How does a principal clinical data manager typically collaborate with cross-functional teams during a clinical trial?

A Principal Clinical Data Manager frequently partners with clinical operations, biostatistics, medical writers, and regulatory affairs throughout the clinical trial process. They coordinate data collection and validation activities, ensure data quality standards are met, and facilitate clear communication between departments. This role often leads data review meetings, addresses data discrepancies, and supports protocol adherence, making strong collaboration and leadership skills essential for project success.

What are the key skills and qualifications needed to thrive as a principal clinical data manager, and why are they important?

To thrive as a Principal Clinical Data Manager, you need expertise in clinical data management, regulatory compliance (such as GCP), and often a degree in life sciences or a related field. Familiarity with data management systems like Medidata Rave, Oracle Clinical, and knowledge of CDISC standards are typically required, along with certifications like CCDM. Leadership, attention to detail, and strong communication skills help in managing teams and collaborating across functions. These skills ensure data integrity, regulatory adherence, and efficient clinical trial outcomes in a highly regulated industry.

What is the difference between Principal Clinical Data Manager vs Clinical Data Manager?

AspectPrincipal Clinical Data ManagerClinical Data Manager
CredentialsBachelor's/Master's in Life Sciences, Biostatistics, or related field; experience in clinical data managementBachelor's in Life Sciences or related field; some experience in data management
Work EnvironmentLeads data management teams, oversees projects, collaborates with cross-functional teamsPerforms data entry, database setup, and data validation tasks
Employer & IndustryPharmaceutical, biotech, CROsPharmaceutical, biotech, CROs

The Principal Clinical Data Manager typically has more leadership responsibilities and oversees data management processes, while the Clinical Data Manager focuses on executing data entry and validation tasks. Both roles are essential in clinical trials within the pharmaceutical and biotech industries, but the principal role involves higher-level oversight and strategic planning.

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Cities with the most Principal Clinical Data Manager job openings:

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What states have the most Principal Clinical Data Manager jobs?

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Principal Clinical Data Manager jobs near you
Infographic showing various Principal Clinical Data Manager job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 80% Physical, 2% Hybrid, and 18% Remote job distribution, with an average salary of $118,909 per year, or $57.2 per hour.

Senior Clinical Data Manager

Malvern, PA • On-site

Ocugen Inc
Biotechnology Research and Development • 51 - 200 employees
Learn more about Ocugen Incexternal

Other

Re-posted 8 days ago

Key responsibilities

  • Oversee clinical data management efforts, including database design, CRF development, data monitoring, and validation.

  • Lead and mentor data management staff, ensure quality data collection, and manage vendors as needed.

  • Develop and implement data management plans, standard operating procedures, and ensure compliance with regulatory standards.

Job description

Position Summary
The Senior Clinical Data Manager plays a pivotal role within Ocugen's clinical data management team. This individual will lead data management efforts, oversee quality data collection and management processes, and contribute to critical aspects of clinical trial data handling, including database design, CRF development, data monitoring, and validation for clinical development programs and marketed products. In addition to technical responsibilities, the Senior Clinical Data Manager will provide leadership to junior data management staff and work collaboratively across functional teams, ensuring high-quality and timely deliverables.
Responsibilities
  • Oversee studies or a program, ensures cross study consistency, mentors team members, and manage vendors as needed.
  • Makes higher level decisions on data standards, risk based data management strategies, and protocol driven design choices.
  • Leads inspection readiness, ensures documentation completeness across studies,
  • Serves as a subject matter expert during audits, helps standardize SOP alignment, guides the team in applying GCP, ICH, CDISC, and internal compliance expectations.
  • Provides strategic input to Clinical Operations, Biostatistics, Programming, and Quality on data flow, database design improvements, standards adoption, and process optimizations.
  • Represents DM in program level meetings and drives improvements across studies (aligned with broader responsibilities seen in senior and principal level descriptions).
  • Provide mentorship and technical guidance to junior data management staff.
  • Ensure accurate and efficient collection of electronic clinical trial data.
  • Develop and validate edit checks and validation reports to maintain the highest quality data.
  • Ensure all required documentation is completed accurately and promptly across studies.
  • Develop and implement innovative data strategies to streamline data management workflows.
  • Identify and mitigate risks in data management processes proactively.
  • Take the lead on special projects and additional tasks as required by management.
  • Lead the development and execution of data management plans (DMPs), ensuring seamless data flow from collection to final analysis.
  • Design and oversee program standards and study-specific electronic Case Report Forms (eCRFs).
  • Partner with Biometrics, Clinical, and Regulatory teams to implement research protocols and ensure proper clinical data outputs for deliverables.
  • Develop and manage data transfer specifications, data review plans, and risk management strategies.
  • Collaborate on cross-functional project timelines and ensure database deliverables are achieved within schedule and quality standards.
  • Author and revise standard operating procedures (SOPs) and study-specific DMPs.
  • Prepare for and participate in audits, ensuring data management processes meet compliance standards.

  • BS degree in clinical, biological or mathematical sciences, or related field, or nursing qualification, or work- related equivalent.
  • 5-7 years of clinical data management experience in biopharma or CRO environment.
  • Strong attention to detail and motivation to provide quality deliverables.
  • Able to work in a fast-paced environment.
  • Experience with clinical trials.
  • Experience with CRFs, and in the development process of EDC databases, IRT systems and diary applications for data collection. Veeva experience is preferred.
  • Strong knowledge of GCPs, ICH, FDA, and CDISC regulatory requirements governing clinical studies.
  • Demonstrated attention to detail and outstanding organization skills.
  • Self-motivated with a commitment to high quality, on-time deliverables.
  • Excellent communication and collaboration skills with a team-oriented approach.
  • Demonstrated ability to identify and resolve issues and effectively manage timelines.

Working Conditions
This position operates in an office setting, in person. Remote work will be limited. Job may additionally require incumbent to be available outside of these hours to handle priority business needs.
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About Ocugen

Sourced by ZipRecruiter

Industry

Biotechnology research and development

Company size

51 - 200 Employees

Headquarters location

Malvern, PA, US

Year founded

2013

Social media

Twitter

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