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Preclinical Research Engineer Jobs in Raleigh, NC

Working collaboratively with faculty, scientists, and engineers, the Research Associate, Senior will contribute to translational research bridging preclinical discovery and human applications ...

... engineered mouse models, patient-derived models, single-cell and spatial genomics, organoid systems, and preclinical therapeutic studies. Learn more about our research by visiting or searching ...

... engineered mouse models, patient-derived models, single-cell and spatial genomics, organoid systems, and preclinical therapeutic studies. Learn more about our research by visiting or searching ...

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Preclinical Research Engineer information

See Raleigh, NC salary details

$36K

$103.1K

$138.5K

How much do preclinical research engineer jobs pay per year?

As of Jul 31, 2026, the average yearly pay for preclinical research engineer in Raleigh, NC is $103,053.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,100.00 and $101,100.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Preclinical Research Engineer, and why are they important?

To thrive as a Preclinical Research Engineer, you need a solid background in biomedical engineering, biology, or a related field, along with experience in experimental design and data analysis. Familiarity with laboratory instrumentation, imaging systems, Good Laboratory Practice (GLP) standards, and relevant software such as MATLAB or statistical tools is crucial. Strong problem-solving abilities, attention to detail, and effective collaboration skills help set exceptional candidates apart. These competencies are vital for ensuring high-quality research outcomes, regulatory compliance, and successful cross-disciplinary teamwork in the preclinical development process.

What are preclinical research engineers?

Preclinical research engineers are professionals who design, develop, and test medical devices, pharmaceuticals, or other health-related products in the preclinical stage before they are used in human trials. They work with scientists and medical experts to ensure products meet safety and regulatory standards by conducting laboratory research, animal studies, and data analysis. Their work is crucial in identifying potential issues early and ensuring that only the safest and most effective products move forward to clinical trials.

What are some common challenges faced by Preclinical Research Engineers when transitioning new devices from concept to animal studies?

Preclinical Research Engineers often encounter challenges related to regulatory compliance, experimental design, and cross-functional collaboration when moving new devices from the conceptual phase to animal testing. Ensuring that prototypes meet safety and ethical standards while generating reliable, reproducible data can be complex and requires meticulous planning. Additionally, close coordination with biologists, veterinarians, and regulatory experts is essential to address issues such as animal welfare, data integrity, and timely project milestones. Being proactive in communication and documentation helps navigate these challenges and supports successful project advancement.

What is the difference between Preclinical Research Engineer vs Laboratory Technician?

AspectPreclinical Research EngineerLaboratory Technician
Required CredentialsBachelor's or Master's in Biomedical, Biological, or related fields; some roles may require certifications in lab techniquesAssociate's or Bachelor's degree; technical training or certifications often preferred
Work EnvironmentResearch labs, pharmaceutical companies, biotech firms, often involved in experimental design and data analysisLaboratories performing routine testing, sample preparation, and data recording
Employer & Industry UsageUsed in biotech, pharmaceutical, and research institutions focusing on preclinical studiesCommon in hospitals, research labs, and manufacturing settings for routine lab work

Preclinical Research Engineers focus on designing and conducting experiments to evaluate new drugs or therapies before clinical trials, requiring advanced education and analytical skills. Laboratory Technicians perform routine lab tasks, supporting research activities with less emphasis on experimental design. Both roles are essential in the research process but differ in responsibilities and qualifications.

What are popular job titles related to Preclinical Research Engineer jobs in Raleigh, NC? For Preclinical Research Engineer jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Preclinical Research Engineer jobs in Raleigh, NC look for? The top searched job categories for Preclinical Research Engineer jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Preclinical Research Engineer jobs? Cities near Raleigh, NC with the most Preclinical Research Engineer job openings:

Postdoctoral Scientist - Neuropharmacology Research

RTI International

Research Triangle Park, NC

Temporary

Medical, Dental, Life, Retirement, PTO

Re-posted 26 days ago


RTI International rating

7.0

Company rating: 7.0 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

61st of 72 rated research


Job description

Why RTI

RTI International is an independent, scientific research institute dedicated to improving the human condition. Our vision is to address the world's most critical problems with technical and science-based solutions in pursuit of a better future. Clients rely on us to answer questions that demand an objective and multidisciplinary approach-one that integrates expertise across social, statistical, data, and laboratory sciences, engineering, and other technical disciplines to solve the world's most challenging problems.We believe in the promise of science and technical solutions, and we push ourselves every day to deliver on that promise for the good of people, communities, and businesses in the US and around the world. If you are looking for the opportunity to make a real difference, RTI is the place for you.

About the Hiring Group

Discovery Sciences at RTI International, located in Research Triangle Park, North Carolina, conducts innovative neuropsychopharmacology research focused on understanding the neural mechanisms underlying reward, stress, and pain. Our multidisciplinary team combines behavioral neuroscience, pharmacology, and advanced neural recording and manipulation techniques to support high-quality translational research. We are seeking a full-time Research Associate to contribute to and help manage a dynamic nonclinical and preclinical research program involving behavioral and neurophysiological studies in rodents.

What You'll Do

As a Research Associate, you will play a key role in conducting and managing neuropsychopharmacology studies involving behaving rodents. This position requires both hands-on laboratory expertise and strong organizational skills to support complex research projects from planning through execution, analysis, and reporting. You will work closely with investigators and collaborators while helping maintain a high standard of scientific rigor, regulatory compliance, and laboratory operations.

Responsibilities:

  • Conduct behavioral and pharmacological dosing experiments in rodents.
  • Perform rodent surgeries, including intracranial procedures, and provide pre- and post-operative care.
  • Manipulate and monitor neural activity in rodents engaged in behavioral tasks.
  • Maintain oversight of laboratory rodents, including monitoring animal health and welfare.
  • Maintain accurate behavioral observations, experimental records, and data collection documentation.
  • Review study data and associated records to ensure accuracy, completeness, and quality.

In addition to experimental work, you will help ensure smooth laboratory operations and regulatory readiness. This includes maintaining laboratory resources, supporting staff development, and contributing to scientific communication and dissemination.

Additional responsibilities include:

  • Obtain, maintain, and inventory laboratory supplies and records.
  • Maintain and troubleshoot laboratory equipment as needed.
  • Ensure experiments are conducted in strict accordance with established protocols and applicable regulations, including NIH, GLP, and DEA requirements when necessary.
  • Prepare for and assist with laboratory inspections and audits.
  • Assist with training and mentoring new or less experienced staff members.
  • Prepare written and oral reports and maintain clear communication with supervisors, colleagues, and external collaborators.
  • Publish and present scientific findings in peer-reviewed journals and professional conferences.
  • Occasionally support weekend, holiday, or evening work as research activities require.
What You'll NeedRequired Qualifications:
  • Doctoral degree in a relevant scientific discipline such as neuroscience, pharmacology, psychology, or a related field.
  • Minimum of 3 years of experience working with behavioral and/or pharmacological rodent models.
  • Strong written and verbal communication skills.
  • Ability to work collaboratively while meeting aggressive project timelines and deliverables.
Preferred Qualifications:
  • Experience with neural recording techniques and analysis of neurophysiological datasets.
  • Experience with microscopy methods and related data interpretation.
  • Proficiency with computational and statistical analysis tools such as MATLAB, Python, R, and other relevant software.
EEO & Pay Equity Statements

For San Francisco, CA USA Job Postings Only: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Further information is available here.

RTI accepts applications to our job openings from candidates with criminal histories or conviction records in accordance with all applicable laws, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

For Applicants in Massachusetts Only: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

The anticipated pay range for this role is listed below. Our pay ranges represent national averages and may vary by location as a geographic differential may be applied to some locations within the United States. RTI considers multiple factors when making an offer including, for example: established salary range, internal budget, business needs, and education and years of work experience possessed by the applicant. Further, salary is merely one element to our offer.

At RTI, we demonstrate our commitment to rewarding individual and team achievement through a total rewards package. This package includes (among other things) a competitive base salary, a generous paid time off policy, merit based annual increases, bonus opportunities and a robust recognition program. Other benefits include a competitive range of insurance plans (including health, dental, life, and short-term and long-term disability), access to a retirement savings program such as a 401(k) plan, paid parental leave for all parents, financial assistance with adoption expenses or infertility treatments, financial reimbursement for education and developmental opportunities, an employee assistance program, and numerous other offerings to support a healthy work-life balance.

Hiring Salary Range$55,000 - $60,000Employment Type: TEMPORARY

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