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Postdoctoral Enzyme Jobs in Colorado (NOW HIRING)

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

A Postdoctoral Associate position is available immediately in the laboratory of Elan Eisenmesser at ... in enzyme mechanisms. * Macromolecular assemblies involved in microbial metabolism with a ...

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

S. citizens or permanent residents enrolled in a research or clinical doctoral or postdoctoral ... enzyme-linked immune-sorbent assay (ELISA), western blotting). * Background in immunology ...

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

S. citizens or permanent residents enrolled in a research or clinical doctoral or postdoctoral ... enzyme-linked immune-sorbent assay (ELISA), western blotting). * Background in immunology ...

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

A Postdoctoral Associate position is available immediately in the laboratory of Elan Eisenmesser at ... in enzyme mechanisms. * Macromolecular assemblies involved in microbial metabolism with a ...

Postdoctoral Enzyme information

What is a postdoctoral enzyme researcher?

Postdoctoral Enzyme researchers are scientists who have completed their Ph.D. and are engaged in advanced study and research focused on enzymes. These researchers work in academic, government, or industry labs to investigate enzyme structure, function, and applications in areas like biotechnology, medicine, and environmental science. Their responsibilities often include designing experiments, publishing findings, and collaborating with multidisciplinary teams. The position is typically temporary and aims to further develop expertise and prepare for independent research careers.

What are the key skills and qualifications needed to thrive as a postdoctoral enzyme researcher?

To thrive as a Postdoctoral Enzyme Researcher, you need a PhD in biochemistry, molecular biology, or a related field, with expertise in enzyme kinetics, protein purification, and experimental design. Experience with analytical tools like HPLC, mass spectrometry, and techniques such as site-directed mutagenesis, along with proficiency in scientific software, is highly valued. Strong problem-solving abilities, meticulous attention to detail, and effective scientific communication are crucial soft skills. These competencies enable researchers to drive innovative enzyme research, publish impactful findings, and contribute to advancements in biotechnology and medicine.

What are some common challenges faced by postdoctoral enzyme researchers, and how can they be overcome?

Postdoctoral researchers specializing in enzyme research often encounter challenges such as troubleshooting complex experimental protocols, optimizing enzyme expression and purification, and staying current with rapidly evolving methodologies. Collaboration with multidisciplinary teams, including chemists, biochemists, and computational scientists, is crucial for overcoming technical hurdles and generating innovative solutions. Time management and balancing independent research with collaborative projects are also key skills, and proactively seeking mentorship or networking opportunities can help address these challenges and support professional growth.

What are popular job titles related to Postdoctoral Enzyme jobs in Colorado?

For Postdoctoral Enzyme jobs in Colorado, the most frequently searched job titles are:

What cities in Colorado are hiring for Postdoctoral Enzyme jobs?

Cities in Colorado with the most Postdoctoral Enzyme job openings:

Infographic showing various Postdoctoral Enzyme job openings in Colorado as of August 2026, with employment types broken down into 89% Full Time, 9% Part Time, and 2% Contract. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution.

Postdoctoral Researcher - Enzyme engineering for cell-free systems

National Renewable Energy Laboratory

Golden, CO • On-site

$76.60 - $126.40/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 18 days ago


Job description

Job Title

Postdoctoral Researcher – Enzyme Engineering for Cell‑Free Systems

Location

Golden, Colorado

Position Type

Postdoc (Fixed Term), 40 hours per week

Overview

RRES Center at NLR focuses on biological, chemical, and catalytic research in polymer design, upcycling, separations, synthetic biology, bioconversion, analytical sciences, computational modeling, and lignocellulosic chemistry. The successful candidate will work on the DOE‑funded project Integrating cell‑free systems and genome engineering to accelerate biosystems design for carbon‑negative biomanufacturing, developing optimized cell‑free systems for converting C1 substrates to sustainable biofuels and bioproducts.

Responsibilities
  • Identify, express, purify, and assay enzymes from full metabolic pathways.
  • Develop high‑throughput enzymatic assays to validate pathways.
  • Collaborate with data scientists to design efficient cell‑free production pathways.
  • Perform directed evolution, structure‑guided protein engineering, and machine‑learning‑guided protein engineering to improve enzyme and pathway function.
  • Conduct laboratory experiments safely and independently, with minimal supervision.
  • Plan and execute research in collaboration with multidisciplinary teams.
  • Communicate scientific results effectively in written and oral formats.
  • Author peer‑reviewed publications.
  • Work effectively in a large, multidisciplinary, multi‑institutional team of engineers and scientists.
Basic Qualifications
  • Recent PhD graduate within the last three years.
  • Experience with cloning, expression, and purification of proteins.
  • Experience with automation of biochemical assays.
  • Demonstrated experience in enzyme and/or protein engineering.
  • Ability to take initiative to set direction and goals for assigned tasks.
  • Strong troubleshooting and problem‑solving skills.
  • Strong record of quality peer‑reviewed publications.
  • Excellent safety record.
  • Ability to follow complex standard operating procedures with attention to detail.
Preferred Qualifications
  • Analytical chemistry experience with HPLC, GC‑FID, GC‑MS, and/or LC‑MS.
Annual Salary Range

$76,600 – $126,400

Benefits Summary
  • Medical, dental, and vision insurance.
  • Short‑term disability insurance.
  • Pension benefits.
  • 403(b) employee savings plan with employer match.
  • Life and accidental death and dismemberment insurance.
  • Personal time off and sick leave; paid holidays.
  • Possible performance‑, merit‑, and achievement‑based awards.
  • Possible relocation expense reimbursement.
Equal Opportunity Employer

All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity, genetic information, marital status, domestic partner status, military or veteran status, national origin, ancestry, race, religion, creed, sex, pregnancy, childbirth, breastfeeding, sexual orientation, or any other status protected by federal, state, or local law.

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