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Portfolio Strategy Manager Biotech Jobs (NOW HIRING)

Job Title Portfolio Strategy Director Summary As the Portfolio Strategy Director, you lead ... Coordinate inputs from Transactions, Workplace/Occupancy Planning, Facilities Management, Finance ...

Job Title Portfolio Strategy Director Summary As the Portfolio Strategy Director, you lead ... Coordinate inputs from Transactions, Workplace/Occupancy Planning, Facilities Management, Finance ...

Director, Portfolio Strategy & Private Markets What can you expect: This is a fantastic opportunity ... Working closely with senior Portfolio Management leaders and the Alternatives Investment Director ...

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Portfolio Strategy Manager Biotech information

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$37K

$100.5K

$187.5K

How much do portfolio strategy manager biotech jobs pay per year?

As of Sep 12, 2026, the average yearly pay for portfolio strategy manager biotech in the United States is $100,458.00, according to ZipRecruiter salary data. Most workers in this role earn between $65,500.00 and $130,000.00 per year, depending on experience, location, and employer.

What does a portfolio strategy manager do in biotech?

A Portfolio Strategy Manager in the biotech industry oversees a company's portfolio of drug candidates, technologies, or products to ensure strategic alignment with business goals. They analyze market trends, assess the value and risks of different projects, and prioritize investments to maximize return and advance the organization's objectives. This role often involves collaborating with research, development, and commercial teams to make data-driven decisions about which programs to advance, partner, or discontinue. Their ultimate goal is to optimize the company's resources and ensure long-term growth and competitiveness.

What are the key skills and qualifications needed to thrive as a portfolio strategy manager in biotech?

A Portfolio Strategy Manager in Biotech needs expertise in life sciences, strategic planning, and financial analysis, often supported by an advanced degree (such as an MBA or PhD) and relevant industry experience. Familiarity with portfolio management tools, data analytics platforms, and project management software is typically required. Strong leadership, analytical thinking, and effective communication skills help drive cross-functional alignment and informed decision-making. These capabilities are crucial for optimizing R&D investments, managing risk, and ensuring the biotech portfolio aligns with business objectives.

How does a portfolio strategy manager in biotech typically collaborate with cross-functional teams to drive project success?

A Portfolio Strategy Manager in biotech works closely with cross-functional teams—including R&D, clinical operations, regulatory, commercial, and finance—to align project goals with broader organizational objectives. They facilitate regular meetings, ensure clear communication of priorities, and help resolve resource allocation challenges. By integrating feedback from diverse stakeholders, they develop actionable portfolio strategies that balance risk, opportunity, and long-term value. This collaborative approach is essential for advancing promising assets through the pipeline and adapting to the rapidly evolving biotech landscape.

What is the difference between Portfolio Strategy Manager Biotech vs Product Manager Biotech?

AspectPortfolio Strategy Manager BiotechProduct Manager Biotech
Primary FocusDeveloping and managing a portfolio of biotech assets and investmentsOverseeing the development and marketing of specific biotech products
ResponsibilitiesStrategic portfolio planning, resource allocation, lifecycle managementProduct lifecycle management, market analysis, cross-functional coordination
Required SkillsStrategic thinking, industry knowledge, financial analysisProduct development, market research, project management
Work EnvironmentCorporate strategy teams, investment firms, biotech companiesR&D departments, marketing teams, biotech firms

The main difference is that Portfolio Strategy Managers focus on managing a collection of biotech assets and investments strategically, while Product Managers concentrate on the development and marketing of individual biotech products. Both roles require industry knowledge but differ in scope and responsibilities.

What are popular job titles related to Portfolio Strategy Manager Biotech jobs?

For Portfolio Strategy Manager Biotech jobs, the most frequently searched job titles are:

Infographic showing various Portfolio Strategy Manager Biotech job openings in the United States as of September 2026, with employment types broken down into 86% Full Time, 13% Part Time, and 1% Contract. Highlights an 86% Physical, 2% Hybrid, and 12% Remote job distribution, with an average salary of $100,458 per year, or $48.3 per hour.

Portfolio Strategy Director

Remote

Cushman & Wakefield
Real Estate • 10K+ employees

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 4 days ago


Cushman & Wakefield rating

7.4

Company rating: 7.4 out of 10

Based on 160 frontline employees who took The Breakroom Quiz


Job description

Job Title

Portfolio Strategy Director

Job Description Summary

As the Portfolio Strategy Director, you lead portfolio strategy, executive decision support, and stakeholder alignment for complex corporate real estate initiatives. You will translate business demand, real estate supply options, stakeholder needs, financial considerations, and portfolio data into executive-ready options, tradeoffs, and portfolio actions that help clients make confident, aligned, and timely decisions.
As a member of Cushman & Wakefield's Portfolio Advisory Group, the Portfolio Strategy Director will be dedicated to one or more of Cushman & Wakefield's most dynamic client accounts. In this role, you will collaborate closely with peers and the account team to support a client's strategic real estate vision. The Portfolio Strategy Director will embody our team philosophy "Client First, Insight Always, Execution Excellence", ensuring every deliverable reflects the team's commitment to innovation, collaboration, and measurable impact.

Job Description

Portfolio Strategy & Decision Support

  • Lead portfolio strategy activities that connect business growth forecasts, utilization insights, real estate alternatives, financial considerations, and operational requirements into actionable recommendations.

  • Develop real estate scenarios that clarify options, tradeoffs, risks, dependencies, sequencing, and recommended paths forward for client and account leadership.

  • Translate business strategy and stakeholder needs into real estate requirements and initiatives, including what space is needed, where options exist, and how decisions support broader portfolio objectives.

Executive Business Case Development

  • Lead development of executive-ready business case memos for renewals, consolidations, new sites, dispositions, relocations, and capital projects.

  • Structure business cases using consistent frameworks, templates, and decision-support standards that improve clarity, comparability, and speed to decision.

  • Partner with Finance and other stakeholders to interpret financial impacts, pressure-test assumptions, and translate investment tradeoffs into executive-ready recommendations.

  • Package complex inputs into concise narratives, recommendations, FAQs, and leadership updates that support executive decision-making.

Cross-Functional Stakeholder Alignment

  • Coordinate inputs from Transactions, Workplace/Occupancy Planning, Facilities Management, Finance, Design & Construction, and Physical Security to support integrated portfolio recommendations.

  • Facilitate alignment among client, account, and functional stakeholders to support decision-making readiness and implementation planning.

  • Synthesize diverse stakeholder perspectives into a cohesive point of view that clearly explains the decision, rationale, options considered, and recommended next steps.

  • Drive proactive information gathering across functional partners to ensure business cases and recommendations are complete, timely, and supported by the right inputs.

Portfolio Governance & Reporting

  • Oversee recurring and ad hoc portfolio reporting in partnership with Data & Analytics, including trend analysis, critical dates, portfolio opportunities, and decision-support insights.

  • Maintain governance tools including decision logs, action trackers, and risk/dependency registers to support executive planning and accountability.

  • Ensure reporting outputs provide clear visibility into portfolio performance, emerging issues, and required decisions.

Process Improvement & Innovation

  • Improve business case, reporting, and governance processes to increase consistency, efficiency, scalability, and stakeholder confidence.

  • Standardize decision frameworks, reporting routines, templates, and stakeholder communications that support repeatable advisory delivery.

  • Identify and implement opportunities to use technology, automation, and AI-enabled tools to improve research, reporting, information synthesis, and strategic decision-support activities.


Cushman & Wakefield also provides eligible employees with an opportunity to enroll in a variety of benefit programs, generally including health, vision, and dental insurance, flexible spending accounts, health savings accounts, retirement savings plans, life, and disability insurance programs, and paid and unpaid time away from work. In addition to a comprehensive benefits package, Cushman and Wakefield provide eligible employees with competitive pay, which may vary depending on eligibility factors such as geographic location, date of hire, total hours worked, job type, business line, and applicability of collective bargaining agreements.
The compensation that will be offered to the successful candidate will depend on factors such as whether the position is covered by a collective bargaining agreement, the geographic area in which the work will be performed, market pay rates in that area, and the candidate's experience and qualifications.
The company will not pay less than minimum wage for this role.
The compensation for the position is: $ 148,750.00 - $175,000.00Cushman & Wakefield is an Equal Opportunity employer to all protected groups, including protected veterans and individuals with disabilities. Discrimination of any type will not be tolerated.

In compliance with the Americans with Disabilities Act Amendments Act (ADAAA), if you have a disability and would like to request an accommodation in order to apply for a position at Cushman & Wakefield, please call the ADA line at 1-888-365-5406 or emailAccommodations@cushwake.com. Please refer to the job title and job location when you contact us.

INCO: "Cushman & Wakefield"

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